Results 201 to 210 of about 157,128 (255)
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Nature Reviews Disease Primers, 2017
Chronic pancreatitis is defined as a pathological fibro-inflammatory syndrome of the pancreas in individuals with genetic, environmental and/or other risk factors who develop persistent pathological responses to parenchymal injury or stress. Potential causes can include toxic factors (such as alcohol or smoking), metabolic abnormalities, idiopathic ...
Kleeff, Jorg +11 more
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Chronic pancreatitis is defined as a pathological fibro-inflammatory syndrome of the pancreas in individuals with genetic, environmental and/or other risk factors who develop persistent pathological responses to parenchymal injury or stress. Potential causes can include toxic factors (such as alcohol or smoking), metabolic abnormalities, idiopathic ...
Kleeff, Jorg +11 more
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Current Opinion in Gastroenterology, 2002
The pathogenesis of idiopathic chronic pancreatitis remains poorly understood despite the high expectations for ascribing the pancreatic damage in affected patients to genetic defects. Neither mutations in the cationic trypsinogen gene nor mutations of the cystic fibrosis conductance regulator gene account for the chronic pancreatitis noted in most ...
Peter, Draganov, Phillip P, Toskes
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The pathogenesis of idiopathic chronic pancreatitis remains poorly understood despite the high expectations for ascribing the pancreatic damage in affected patients to genetic defects. Neither mutations in the cationic trypsinogen gene nor mutations of the cystic fibrosis conductance regulator gene account for the chronic pancreatitis noted in most ...
Peter, Draganov, Phillip P, Toskes
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The Lancet, 2020
Chronic pancreatitis is a multifactorial, fibroinflammatory syndrome in which repetitive episodes of pancreatic inflammation lead to extensive fibrotic tissue replacement, resulting in chronic pain, exocrine and endocrine pancreatic insufficiency, reduced quality of life, and a shorter life expectancy.
Georg, Beyer +4 more
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Chronic pancreatitis is a multifactorial, fibroinflammatory syndrome in which repetitive episodes of pancreatic inflammation lead to extensive fibrotic tissue replacement, resulting in chronic pain, exocrine and endocrine pancreatic insufficiency, reduced quality of life, and a shorter life expectancy.
Georg, Beyer +4 more
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Current Opinion in Internal Medicine, 2008
As in previous reviews in this journal, this review is focused on the most important new observations in chronic pancreatitis made in the last year.Important observations included the search for biomarkers and alternative methods for the detection of early chronic pancreatitis; stellate cell activation and their role in fibrogenesis; the natural ...
Darwin L, Conwell, Peter A, Banks
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As in previous reviews in this journal, this review is focused on the most important new observations in chronic pancreatitis made in the last year.Important observations included the search for biomarkers and alternative methods for the detection of early chronic pancreatitis; stellate cell activation and their role in fibrogenesis; the natural ...
Darwin L, Conwell, Peter A, Banks
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Current Opinion in Gastroenterology, 2014
We review selected important clinical observations in chronic pancreatitis reported in 2013.Early diagnosis of chronic pancreatitis remains difficult, although newer techniques utilizing endoscopic ultrasonography-elastography and MRI hold promise. Patients with chronic pancreatitis are at risk of nutritional deficiencies. Osteoporosis, osteopenia, and
Anand R, Gupte, Chris E, Forsmark
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We review selected important clinical observations in chronic pancreatitis reported in 2013.Early diagnosis of chronic pancreatitis remains difficult, although newer techniques utilizing endoscopic ultrasonography-elastography and MRI hold promise. Patients with chronic pancreatitis are at risk of nutritional deficiencies. Osteoporosis, osteopenia, and
Anand R, Gupte, Chris E, Forsmark
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Current Opinion in Gastroenterology, 2007
As in previous reviews in this journal, this review is focused on the most important new observations in chronic pancreatitis made in the past year and the beginning of this year.Important observations include the following: first, the natural history and course of chronic pancreatitis; second, that smoking enhances the risk of chronic pancreatitis ...
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As in previous reviews in this journal, this review is focused on the most important new observations in chronic pancreatitis made in the past year and the beginning of this year.Important observations include the following: first, the natural history and course of chronic pancreatitis; second, that smoking enhances the risk of chronic pancreatitis ...
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The Lancet, 2016
Chronic pancreatitis describes a wide spectrum of fibro-inflammatory disorders of the exocrine pancreas that includes calcifying, obstructive, and steroid-responsive forms. Use of the term chronic pancreatitis without qualification generally refers to calcifying chronic pancreatitis.
Shounak, Majumder, Suresh T, Chari
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Chronic pancreatitis describes a wide spectrum of fibro-inflammatory disorders of the exocrine pancreas that includes calcifying, obstructive, and steroid-responsive forms. Use of the term chronic pancreatitis without qualification generally refers to calcifying chronic pancreatitis.
Shounak, Majumder, Suresh T, Chari
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Current Opinion in Gastroenterology, 1999
An increasing number of novel mutations are associated with chronic pancreatitis. Some cause a high-penetrance, autosomal dominant type of clinical picture (eg, mutations at codons 29 and 122 of the cationic trypsinogen gene), whereas others have a low penetrance or are frequent in the general population (eg, mutations in Kazal type 1 [SPINK1] and in ...
S T, Chari, E P, Dimagno
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An increasing number of novel mutations are associated with chronic pancreatitis. Some cause a high-penetrance, autosomal dominant type of clinical picture (eg, mutations at codons 29 and 122 of the cationic trypsinogen gene), whereas others have a low penetrance or are frequent in the general population (eg, mutations in Kazal type 1 [SPINK1] and in ...
S T, Chari, E P, Dimagno
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Scandinavian Journal of Gastroenterology, 1996
Chronic pancreatitis is a serious disease with many yet unsolved problems, e.g. pathogenesis, cause of pain and treatment. Danish gastroenterologists have for many years participated actively in the investigation of the disease and have produced many internationally recognized results, especially regarding secretion physiology and pathophysiology ...
N T, Pedersen, H, Worning
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Chronic pancreatitis is a serious disease with many yet unsolved problems, e.g. pathogenesis, cause of pain and treatment. Danish gastroenterologists have for many years participated actively in the investigation of the disease and have produced many internationally recognized results, especially regarding secretion physiology and pathophysiology ...
N T, Pedersen, H, Worning
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The American Journal of the Medical Sciences, 1910
Chronic pancreatitis is a challenging condition for a variety of reasons: it is relatively poorly understood, difficult to diagnose, complex to manage, and is associated with significant morbidity and mortality. The aim of this article is to outline the important aspects of this fibro-inflammatory disease, highlighting the difficulties and providing ...
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Chronic pancreatitis is a challenging condition for a variety of reasons: it is relatively poorly understood, difficult to diagnose, complex to manage, and is associated with significant morbidity and mortality. The aim of this article is to outline the important aspects of this fibro-inflammatory disease, highlighting the difficulties and providing ...
openaire +1 more source