Results 11 to 20 of about 297,882 (348)

Therapies for Chronic Allograft Rejection [PDF]

Frontiers in Pharmacology, 2021
Remarkable advances have been made in the pathophysiology, diagnosis, and treatment of antibody-mediated rejection (ABMR) over the past decades, leading to improved graft outcomes.
Min Young Kim, Daniel C. Brennan
doaj   +3 more sources

Mechanisms of chronic rejection

Transplantation Proceedings, 1999
P Häyry, Einari Aavik, H Savolainen
openalex   +4 more sources

Allograft or Recipient ST2 Deficiency Oppositely Affected Cardiac Allograft Vasculopathy via Differentially Altering Immune Cells Infiltration

Frontiers in Immunology, 2021
The role of IL-33/ST2 signaling in cardiac allograft vasculopathy (CAV) is not fully addressed. Here, we investigated the role of IL-33/ST2 signaling in allograft or recipient in CAV respectively using MHC-mismatch murine chronic cardiac allograft ...
Zhenggang Zhang, Na Zhang, Junyu Shi, Chan Dai, Suo Wu, Mengya Jiao, Xuhuan Tang, Yunfei Liu, Xiaoxiao Li, Yong Xu, Zheng Tan, Zheng Tan, Feili Gong, Fang Zheng, Fang Zheng   +14 more
doaj   +1 more source

Immune Checkpoints Expression in Chronic Lung Allograft Rejection

Frontiers in Immunology, 2021
Chronic lung allograft dysfunction (CLAD) is the main cause of poor survival and low quality of life of lung transplanted patients. Several studies have addressed the role of dendritic cells, macrophages, T cells, donor specific as well as anti-HLA ...
Ilaria Righi, Valentina Vaira, Valentina Vaira, Letizia Corinna Morlacchi, Giorgio Alberto Croci, Giorgio Alberto Croci, Valeria Rossetti, Francesco Blasi, Francesco Blasi, Stefano Ferrero, Stefano Ferrero, Mario Nosotti, Mario Nosotti, Lorenzo Rosso, Lorenzo Rosso, Mario Clerici, Mario Clerici   +16 more
doaj   +1 more source

Chronic rejection. [PDF]

Journal of the American Society of Nephrology, 1994
Current immunosuppressive protocols have significantly decreased graft loss to acute rejection but have had no effect on graft loss to chronic rejection. Recently, attention has been focused on the prevention and management of chronic rejection. Centers must come to a uniform definition of this phenomenon so that studies can be compared. It is believed
A J, Matas, J F, Burke, G A, DeVault, A, Monaco, J D, Pirsch   +4 more
openaire   +2 more sources

Single-Cell RNA Sequencing Reveals the Immunological Profiles of Renal Allograft Rejection in Mice

Frontiers in Immunology, 2021
Allograft rejection is a common immunological feature in renal transplantation and is associated with reduced graft survival. A mouse renal allograft rejection model was induced and single-cell RNA sequencing (scRNA-seq) data of CD45+ leukocytes in ...
Qixia Shen, Qixia Shen, Qixia Shen, Qixia Shen, Yucheng Wang, Yucheng Wang, Yucheng Wang, Jiaoyi Chen, Lifeng Ma, Xiaoru Huang, Xiaoru Huang, Sydney C. W. Tang, Huiyao Lan, Hong Jiang, Hong Jiang, Hong Jiang, Jianghua Chen, Jianghua Chen, Jianghua Chen   +18 more
doaj   +1 more source

Tolerance and chronic rejection [PDF]

Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 2001
The most common cause of chronic allograft loss is an incompletely understood clinicopathological entity called chronic rejection (CR). Recent reports suggest an improvement in long–term renal allograft survival, although it is not clear from these data whether a true reduction of biopsy–proven CR has occurred.
Richard S. Lee, Karl L. Womer, Joren C. Madsen, Mohamed H. Sayegh   +3 more
openaire   +3 more sources

Alemtuzumab as a Therapy for Chronic Lung Allograft Dysfunction in Lung Transplant Recipients With Short Telomeres

Frontiers in Immunology, 2020
Alemtuzumab, a monoclonal antibody targeting CD52 that causes lymphocyte apoptosis, is a form of advanced immunosuppression that is currently used as a therapy for refractory acute cellular rejection and chronic lung allograft dysfunction in lung ...
Anil J. Trindade, Anil J. Trindade, Anil J. Trindade, Tany Thaniyavarn, Tany Thaniyavarn, Keri Townsend, Robin Klasek, Karen P. Tsveybel, John C. Kennedy, John C. Kennedy, Hilary J. Goldberg, Hilary J. Goldberg, Souheil El-Chemaly, Souheil El-Chemaly   +13 more
doaj   +1 more source

A comparative histological analysis of early and late graft dysfunction in different time zones following living donor liver transplantation

Indian Journal of Pathology and Microbiology, 2022
Background: Liver biopsy plays a crucial role in evaluating allograft dysfunction. Comprehensive analysis of the histological spectrum of complications, particularly rejection, in different time zones is lacking.
Archana Rastogi, Nayana Patil, Sphurti Srivastava, Gayatri Ramakrishna, Rakhi Maiwal, Guresh Kumar, Ashok K Choudhary, Seema Alam, Chhagan Bihari, Viniyendra Pamecha   +9 more
doaj   +1 more source

Cold Ischemia Time and Graft Fibrosis Are Associated with Autoantibodies after Pediatric Liver Transplantation: A Retrospective Cohort Study of the European Reference Network TransplantChild

Children, 2022
The reported prevalence of autoantibodies (AAB) (ANA, SMA, LKM, SLA) after pediatric liver transplantation (pLTX) varies considerably from 26–75%, but their clinical impact on outcome is uncertain.
Norman Junge, Angelo Di Giorgio, Muriel Girard, Zeynep Demir, Diana Kaminska, Maria Janowska, Vaidotas Urbonas, Dominykas Varnas, Giuseppe Maggiore, Tommaso Alterio, Christoph Leiskau, Florian W. R. Vondran, Nicolas Richter, Lorenzo D’Antiga, Rafael Mikolajczyk, Eva-Doreen Pfister, Ulrich Baumann   +16 more
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