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Therapies for Chronic Allograft Rejection [PDF]
Frontiers in Pharmacology, 2021 Remarkable advances have been made in the pathophysiology, diagnosis, and treatment of antibody-mediated rejection (ABMR) over the past decades, leading to improved graft outcomes.
Min Young Kim, Daniel C. Brennan
doaj +4 more sources
M2 Macrophages Serve as Critical Executor of Innate Immunity in Chronic Allograft Rejection [PDF]
Frontiers in Immunology, 2021 Allograft functional failure due to acute or chronic rejection has long been a major concern in the area of solid organ transplantation for decades. As critical component of innate immune system, the macrophages are unlikely to be exclusive for driving ...
Hanwen Zhang, Zhuonan Li, Wei Li
doaj +3 more sources
The common rejection module in chronic rejection post lung transplantation. [PDF]
PLoS ONE, 2018 RATIONALE:Recent studies suggest that similar injury mechanisms are in place across different solid organ transplants, resulting in the identification of a common rejection module (CRM), consisting of 11 genes that are overexpressed during acute and, to ...
Annelore Sacreas +9 more
doaj +3 more sources
Chronic Childhood Peer Rejection is Associated with Heightened Neural Responses to Social Exclusion During Adolescence [PDF]
Journal of Abnormal Child Psychology, 2015 This functional Magnetic Resonance Imaging (fMRI) study examined subjective and neural responses to social exclusion in adolescents (age 12-15) who either had a stable accepted (n = 27; 14 males) or a chronic rejected (n = 19; 12 males) status among ...
Berna Güroğlu +3 more
core +6 more sources
Clinics, 2016 OBJECTIVE: Chronic rejection remains a major cause of graft failure with indication for re-transplantation. The incidence of chronic rejection remains high in the pediatric population.
Ana Cristina Aoun Tannuri +4 more
doaj +2 more sources
Chronic Rejection After Kidney Transplantation. [PDF]
TransplantationIn kidney transplantation, ongoing alloimmune processes—commonly triggered by HLA incompatibilities—can trigger chronic transplant rejection, affecting the microcirculation and the tubulointerstitium. Continuous inflammation may lead to progressive, irreversible graft injury, culminating in graft dysfunction and accelerated transplant failure. Numerous
Diebold M +5 more
europepmc +3 more sources
Microchimerism as Post-Transplant Marker of a Chronic Rejection Process. [PDF]
Int J Mol Sci, 2023 Sieńko J +8 more
europepmc +3 more sources
Pathogenesis of chronic allograft rejection [PDF]
Transplant International, 2003 Chronic allograft nephropathy (CAN) is, besides death of the recipient with graft function, the most common cause of renal transplant loss. It is characterized by loss of function and replacement of tissue by fibrotic material. The pathogenesis is not clear, but seems to be multifactorial and involves events both early and late after transplantation ...
Simone A, Joosten +2 more
openaire +3 more sources
From Transplant to Reamputation: A Case Report on Chronic Rejection and Innovative Treatment in Hand Allotransplantation [PDF]
Plastic and Reconstructive Surgery, Global OpenSummary:. Vascularized composite allotransplantation provides upper limb amputation patients with functional and aesthetic restoration but is limited by the challenges of chronic rejection.
Ahmed Elsaftawy, MD, PhD +6 more
doaj +2 more sources
Pericytes, Microvasular Dysfunction, and Chronic Rejection [PDF]
Transplantation, 2015 Chronic rejection of transplanted organs remains the main obstacle in the long-term success of organ transplantation. Thus, there is a persistent quest for development of antichronic rejection therapies and identification of novel molecular and cellular targets.
Kloc, Malgorzata +3 more
openaire +3 more sources