Results 221 to 230 of about 3,305,589 (380)

Gut Microbiota‐Non‐Coding RNA Axis in Immune Modulation and Disease: From Mechanisms to Clinical Translation

Advanced Science, EarlyView.
ABSTRACT Immune homeostasis is indispensable for preserving organismal integrity, orchestrated through complex molecular networks encompassing immune cell dynamics, microbial cues, and epigenetic regulation. Among these, the gut microbiota‐non‐coding RNA (ncRNA) axis has recently garnered substantial attention as a multifaceted modulator of host ...
Bonan Chen, Guoming Chen, Xieyuan Leng, Qianfan Li, Wenhao Wu, Wenqiu Wu, Zixuan Liu, Zilan Zhong, Xiaohong Zheng, Wei Kang, Fazheng Ren, Yigan Zhang, Juan Chen   +12 more
wiley   +1 more source

Dysregulated Treg repair responses lead to chronic rejection after heart transplantation. [PDF]

J Clin Invest
Warunek JJ, Fan L, Zhang X, Wang S, Sanders SM, Li T, Mathews LR, Dwyer GK, Wood-Trageser MA, Traczek S, Lesniak A, Baron K, Spencer H, Bou Saba J, León Colón E, Tabib T, Lafyatis R, Ross MA, Demetris AJ, Watkins SC, Webber SA, Abou-Daya KI, Turnquist HR.   +22 more
europepmc   +1 more source

Anti-CD38 and regression of chronic active antibody mediated rejection after kidney transplantation, myth or reality?

Marie Matignon, Philippe Grimbert, Anissa Moktefi, Caroline Pilon   +3 more
openalex   +1 more source

Abstract: Prevention of Ischemic-Reperfusion Injury and Chronic Rejection in a Porcine Vascularized Composite Allotransplantation Model

, 2017
Nicholas L. Robbins, Matthew Wordsworth, Kevin Y. Wu, Samuel Tahk, Warren C. Breidenbach, Vijay S. Gorantla   +5 more
openalex   +1 more source

BHLHE40 Orchestrates Effector Tissue‐Resident Memory CD8+ T Cells and Limits Long‐Term Survival of Kidney Graft

Advanced Science, EarlyView.
An effector subset of TRM, defined as CD49a+PD1hi CD8+ TRM, represents a BHLHE40‐orchestrated resident immune component that, rather than circulating cells, plays as a major contributor to allograft rejection. ABSTRACT Tissue‐resident memory T cells (TRM), which function against tumors, infections, and non‐self antigens in organ transplantation ...
Junbo Li, Bo Yang, Tianhui Pan, Xi Zhou, Zhibo Ma, Du Tang, Bowen Xie, Jing Liu, Zhishui Chen, Peixiang Lan   +9 more
wiley   +1 more source

Targeting the Mapk13‐Tcf1‐Slc7a5 Axis via One‐Carbon Metabolic Regulation to Prevent Chronic Allograft Vasculopathy

Advanced Science, EarlyView.
This study emphasizes the role of the Mapk13‐Tcf1‐Slc7a5‐methionine metabolism axis in stem‐like CD4+ T cells. Moreover, it uncovers the mechanism through which limiting one‐carbon metabolism in CD4+ stem‐like T cells suppresses the tide of chronic allograft vasculopathy, offering potential targets to promote long‐term graft survival.
Wang Yi, Di Wu, Jing Liu, Shi Chen, Liu Song, Bin Xie, Aini Xie, Peixiang Lan, Zhishui Chen   +8 more
wiley   +1 more source

Kidney transplant dysfunction in a patient with COVID - 19 infection: role of concurrent Sars-Cov 2 nephropathy, chronic rejection and vitamin C-mediated hyperoxalosis: case report. [PDF]

BMC Nephrol, 2021
Anandh U, Gowrishankar S, Sharma A, Salama A, Dasgupta I.   +4 more
europepmc   +1 more source

Combined standard immunosuppression and immune checkpoint inhibition for BKPyV+ metastatic renal cell carcinoma of the graft in a kidney transplant recipient with chronic rejection: a case report. [PDF]

Front Oncol
Gandolfini I, Manini M, Benigno GD, Gentile M, Palmisano A, Somenzi D, Gnetti L, Delsante M, Mordà B, D'Angelo M, Salvetti D, Fiaccadori E, Buti S, Maggiore U.   +13 more
europepmc   +1 more source

Intrarenal Complement System Transcripts in Chronic Antibody-Mediated Rejection and Recurrent IgA Nephropathy in Kidney Transplantation [PDF]

, 2018
M Cernoch, Petra Hrubá, Marek Kollár, Petra Mrázová, Lucia Straňavová, Alena Lodererová, Eva Honsová, Ondřej Viklický   +7 more
openalex   +1 more source

Circulating Exosomes with Distinct Properties during Chronic Lung Allograft Rejection

Journal of Immunology, 2018
M. Gunasekaran, Monal Sharma, R. Hachem, R. Bremner, Michael A. Smith, T. Mohanakumar   +5 more
semanticscholar   +1 more source