Immunological Aspects Involved in the Degeneration of Cryopreserved Arterial Allografts
Introduction: Cryopreserved arterial allografts have remained an option in patients requiring distal revascularization or associated with vascular infection, in the absence of a valid autogenous saphenous vein.
Mario González-Gay +7 more
doaj +1 more source
Vascularized composite allotransplantation (VCA) has emerged as a useful reconstructive option for patients suffering from major tissue defects and functional deficits.
B. Kollár +5 more
semanticscholar +1 more source
Tolerance and chronic rejection [PDF]
The most common cause of chronic allograft loss is an incompletely understood clinicopathological entity called chronic rejection (CR). Recent reports suggest an improvement in long–term renal allograft survival, although it is not clear from these data whether a true reduction of biopsy–proven CR has occurred.
K L, Womer +3 more
openaire +2 more sources
LATE RENAL GRAFT REJECTION: PATHOLOGY AND PROGNOSIS
Rejection has always been one of the most important cause of late renal graft dysfunction. Aim of the study was to analyze the prevalence of different clinico-pathological variants of rejection that cause late graft dysfunction, and evaluate their impact
E.S. Stolyarevich +4 more
doaj +1 more source
Reduced CD40L expression on ex vivo activated CD4+T-lymphocytes from patients with excellent renal allograft function measured with a rapid whole blood flow cytometry procedure [PDF]
Background: The CD40-CD40L (CD154) costimulatory pathway plays a critical role in the pathogenesis of kidney allograft rejection. In renal transplant biopsies, CD4+ CD40L+ graft-infiltrating cells were detected during chronic rejection in contrast to ...
Friedrich, N. +5 more
core +1 more source
Experimental diabetes exacerbates skin transplant rejection in rats [PDF]
PURPOSE: To investigate the effect of chronic experimental diabetes on skin allografts in rats as a simple model that could clarify some basic aspects and mechanisms involved in transplant rejection in diabetes compared to normal animals.
Flávio Pola dos Reis +2 more
doaj +3 more sources
Proteomics for rejection diagnosis in renal transplant patients: where are we now? [PDF]
Rejection is one of the key factors that determine the long-term allograft function and survival in renal transplant patients. Reliable and timely diagnosis is important to treat rejection as early as possible.
Gwinner, Wilfried +3 more
core +1 more source
Chronic alloantibody mediated rejection [PDF]
Alloantibodies clearly cause acute antibody mediated rejection, and all available evidence supports their pathogenic etiology in the development of chronic alloantibody mediated rejection (CAMR). But the slow evolution of this disease, the on-going immunosuppression, the variations in titer of alloantibodies, and variation in antigenic targets all ...
R Neal, Smith, Robert B, Colvin
openaire +2 more sources
Improved surgical technique for the establishment of a murine model of aortic transplantation. [PDF]
Aortic allotransplantation is a reliable procedure to study the evolvement of chronic rejection in mice. The progressive nature of this process in mice is characterized by diffuse and concentric myointimal proliferation which is inevitably associated ...
Aitouche, A +6 more
core +1 more source
Ischemia and reperfusion injury in kidney transplantation : relevant mechanisms in injury and repair [PDF]
Ischemia and reperfusion injury (IRI) is a complex pathophysiological phenomenon, inevitable in kidney transplantation and one of the most important mechanisms for non- or delayed function immediately after transplantation.
Berger, Stefan P. +7 more
core +2 more sources

