The effect of small bowel transplantation on the morphology and physiology of intestinal muscle: A comparison of autografts versus allografts in dogs [PDF]
, 1997 The effects of acute (AR) and chronic rejection (CR) on intestinal smooth muscle that are responsible for the dysmotility following small bowel transplantation (SBTX) are incompletely understood. Jejunal and ileal specimens from normal control dogs (n=7),
Bauer, AJ +6 more
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Chronic Rejection of the Liver [PDF]
BioDrugs, 2000 Liver transplantation is now widely recognised as an effective treatment option for patients with advanced liver disease. Many units now achieve greater than 85% survival at 1 year, with the majority of patients having a high quality of life. The maintenance of a high quality of life requires careful clinical management to ensure that the continued ...
Raquel Francine Liermann Garcia +2 more
openalex +4 more sources
Experimental rat models of chronic allograft nephropathy: a review [PDF]
, 2014 Chronic allograft nephropathy (CAN) is the leading cause of late allograft loss after renal transplantation (RT), which continues to remain an unresolved problem. A rat model of CAN was first described in 1969 by White et al. Although the rat model of RT
Haylor, John, Shrestha, Badri
core +2 more sources
Alloimmunity and autoimmunity in chronic rejection [PDF]
Current Opinion in Organ Transplantation, 2010 Recent studies demonstrate an increasing role for alloimmune responses in the disruption of self-tolerance leading to immune responses to self-antigens that play a role in the immunopathogenesis of chronic rejection following solid organ transplantation.
Anil B. Seetharam +2 more
openaire +3 more sources
Annals of Surgery Open, 2023 Objective:. We aim to investigate the effects of genetically based HLA matching on patient and graft survival, and acute and chronic rejection after liver transplantation Background:.
Gautam Kok, MD, PhD +6 more
doaj +1 more source
Cause and timing of first allograft failure in orthotopic liver transplantation: A study of 177 consecutive patients [PDF]
, 1991 The cause and timing of first liver allograft failure was evaluated in 177 patients who underwent a second liver transplant between January 1984 and December 1988.
Busuttil +22 more
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M2 Macrophages Serve as Critical Executor of Innate Immunity in Chronic Allograft Rejection
Frontiers in Immunology, 2021 Allograft functional failure due to acute or chronic rejection has long been a major concern in the area of solid organ transplantation for decades. As critical component of innate immune system, the macrophages are unlikely to be exclusive for driving ...
Hanwen Zhang, Zhuonan Li, Wei Li
doaj +1 more source
The influence of HLA matching on cytomegalovirus hepatitis and chronic rejection after liver transplantation [PDF]
, 1993 Previous findings in liver transplantation patients have raised the concept that HLA plays a dualistic role. HLA matching will reduce rejection but may augment MHC restricted cellular immune mechanisms of liver allograft injury. To evaluate this concept,
Demetris, AJ +9 more
core +1 more source
Baboon-to-human liver transplantation [PDF]
, 1993 Our ability to control both the cellular and humoral components of xenograft rejection in laboratory experiments, together with an organ shortage that has placed limits on clinical transplantation services, prompted us to undertake a liver ...
A Tzakis +43 more
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A histometric analysis of chronically rejected human liver allografts: Insights into the mechanisms of bile duct loss: Direct immunologic and ischemic factors [PDF]
, 1989 Conspicuous pathologic features of chronic liver allograft rejection include bile duct loss and chronic obliterative arteriopathy. A quantitative histometric analysis was performed to document the extent of bile duct loss, the size of the “vanished ...
Belle, S +3 more
core +1 more source