Results 51 to 60 of about 3,305,589 (380)

Non-invasive monitoring of renal transplant recipients: Urinary excretion of soluble adhesion molecules and of the complement-split product C4d [PDF]

, 2003
Background: The number of inducible adhesion molecules known to be involved in cell-mediated allograft rejection is still increasing. In addition, recent data describe complement activation during acute humoral allograft rejection.
Friedrich, N., Getto, R., Lederer, Stephan R., Regenbogen, C., Sitter, Thomas, Toepfer, Marcel   +5 more
core   +1 more source

Extracellular Vesicles Mediate Immune Responses to Tissue-Associated Self-Antigens: Role in Solid Organ Transplantations

Frontiers in Immunology, 2022
Transplantation is a treatment option for patients diagnosed with end-stage organ diseases; however, long-term graft survival is affected by rejection of the transplanted organ by immune and nonimmune responses.
Ranjithkumar Ravichandran, Sandhya Bansal, Mohammad Rahman, Angara Sureshbabu, Narendra Sankpal, Timothy Fleming, Ankit Bharat, Thalachallour Mohanakumar   +7 more
doaj   +1 more source

Marked mitigation of transplant vascular sclerosis in FasL(gld) (CD95L) mutant recipients. I. The role of alloantibodies in the development of chronic rejection [PDF]

, 1999
Background. In the acute rejection of allografts, the interaction between Fas (CD95) and its ligand (FasL; CD95L) has been shown to be involved in mediating apoptotic cell death.
Aitouche, A, Fung, JJ, Rao, AS, Salam, A, Starzl, TE, Subbotin, V, Sun, H, Valdivia, LA   +7 more
core   +1 more source

Chronic allograft rejection [PDF]

Current Opinion in Organ Transplantation, 2015
New developments suggest that the graft itself and molecules expressed within the graft microenvironment dictate the phenotype and evolution of chronic rejection.Once ischemia-reperfusion injury, cellular and humoral immune responses target the microvasculature, the associated local tissue hypoxia results in hypoxia-inducible factor 1α-dependent ...
Johannes, Wedel, Sarah, Bruneau, Nora, Kochupurakkal, Leo, Boneschansker, David M, Briscoe   +4 more
openaire   +2 more sources

Association between a Single Donor TARC/CCL17 Promotor Polymorphism and Obstructive Chronic Lung Allograft Dysfunction after Lung Transplantation

Frontiers in Immunology, 2017
Lung transplantation (LTx) outcome is hampered by development of chronic rejection, often manifested as the bronchiolitis obliterans syndrome (BOS). Low serum levels of thymus and activation-regulated chemokine (TARC/CCL17), a chemoattractant, measured ...
Kevin Budding, Jessica van Setten, Eduard A. van de Graaf, Oliver A. van Rossum, Tineke Kardol-Hoefnagel, Erik-Jan D. Oudijk, C. Erik Hack, C. Erik Hack, C. Erik Hack, Henderikus G. Otten   +9 more
doaj   +1 more source

The effect of small bowel transplantation on the morphology and physiology of intestinal muscle: A comparison of autografts versus allografts in dogs [PDF]

, 1997
The effects of acute (AR) and chronic rejection (CR) on intestinal smooth muscle that are responsible for the dysmotility following small bowel transplantation (SBTX) are incompletely understood. Jejunal and ileal specimens from normal control dogs (n=7),
Bauer, AJ, Halfter, WM, Nomoto, M, Reynolds, JC, Starzl, TE, Sugitani, A, Todo, S   +6 more
core   +1 more source

The Banff 2017 Kidney Meeting Report: Revised diagnostic criteria for chronic active T cell–mediated rejection, antibody‐mediated rejection, and prospects for integrative endpoints for next‐generation clinical trials

American Journal of Transplantation, 2018
The kidney sessions of the 2017 Banff Conference focused on 2 areas: clinical implications of inflammation in areas of interstitial fibrosis and tubular atrophy (i‐IFTA) and its relationship to T cell–mediated rejection (TCMR), and the continued ...
M. Haas, A. Loupy, C. Lefaucheur, C. Roufosse, D. Glotz, D. Serón, B. Nankivell, P. Halloran, R. Colvin, E. Akalin, N. Alachkar, S. Bagnasco, Y. Bouatou, Y. Bouatou, J. Becker, L. Cornell, J. P. Huyen, I. Gibson, E. Kraus, R. Mannon, M. Naesens, V. Nickeleit, P. Nickerson, D. Segev, H. Singh, M. Stegall, P. Randhawa, L. Racusen, K. Solez, M. Mengel   +29 more
semanticscholar   +1 more source

Alemtuzumab as a Therapy for Chronic Lung Allograft Dysfunction in Lung Transplant Recipients With Short Telomeres

Frontiers in Immunology, 2020
Alemtuzumab, a monoclonal antibody targeting CD52 that causes lymphocyte apoptosis, is a form of advanced immunosuppression that is currently used as a therapy for refractory acute cellular rejection and chronic lung allograft dysfunction in lung ...
Anil J. Trindade, Anil J. Trindade, Anil J. Trindade, Tany Thaniyavarn, Tany Thaniyavarn, Keri Townsend, Robin Klasek, Karen P. Tsveybel, John C. Kennedy, John C. Kennedy, Hilary J. Goldberg, Hilary J. Goldberg, Souheil El-Chemaly, Souheil El-Chemaly   +13 more
doaj   +1 more source

Experimental rat models of chronic allograft nephropathy: a review [PDF]

, 2014
Chronic allograft nephropathy (CAN) is the leading cause of late allograft loss after renal transplantation (RT), which continues to remain an unresolved problem. A rat model of CAN was first described in 1969 by White et al. Although the rat model of RT
Haylor, John, Shrestha, Badri
core   +2 more sources

A histometric analysis of chronically rejected human liver allografts: Insights into the mechanisms of bile duct loss: Direct immunologic and ischemic factors [PDF]

, 1989
Conspicuous pathologic features of chronic liver allograft rejection include bile duct loss and chronic obliterative arteriopathy. A quantitative histometric analysis was performed to document the extent of bile duct loss, the size of the “vanished ...
Belle, S, Demetris, AJ, Oguma, S, Starzl, TE   +3 more
core   +1 more source