Results 41 to 50 of about 1,099,815 (209)

A modified renal risk score for Chinese patients with antineutrophil cytoplasmic antibody-associated vasculitis

open access: yesBMC Medicine, 2023
Background The renal risk score (RRS) is a useful tool to predict end-stage renal disease (ESRD) in patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV).
Rui-Xue Wang   +11 more
doaj   +1 more source

Chronic renal disease

open access: yesBMJ, 2002
Early identification and active management of patients with renal impairment in primary care can improve outcomes The number of patients with end stage renal disease is growing worldwide. About 20-30 patients have some degree of renal dysfunction for each patient who needs renal replacement treatment.1 Diabetes and hypertension are the two most common
openaire   +3 more sources

Murine models of renal disease: Possibilities and problems in studies using mutant mice [PDF]

open access: yes, 2000
The elucidation of the pathogenesis of human renal disease at the molecular level has been facilitated by the growing field of gene targeting and the development of mouse strains with single-gene deletions - the `knock-out' mice. Experimental nephrology,
Anders, Hans-Joachim   +1 more
core   +1 more source

Autophagy in Immune-Related Renal Disease

open access: yesJournal of Immunology Research, 2019
Autophagy is an important biology process, central to the maintenance of biology process in both physiological and pathological situations. It is regarded as a “double-edged sword”—exerting both protective and/or detrimental effects.
Xin Ye, Xu-jie Zhou, Hong Zhang
doaj   +1 more source

Management of Pain in Autosomal Dominant Polycystic Kidney Disease and Anatomy of Renal Innervation [PDF]

open access: yes, 2015
Purpose Chronic pain is a prominent feature of autosomal dominant polycystic kidney disease that is difficult to treat and manage, often resulting in a decrease in quality of life.
Bacallao, Robert L.   +4 more
core   +1 more source

Complement Factor H Inhibits Anti-Neutrophil Cytoplasmic Autoantibody-Induced Neutrophil Activation by Interacting With Neutrophils

open access: yesFrontiers in Immunology, 2018
Our previous study demonstrated that plasma levels of complement factor H (FH) were inversely associated with the disease activity of patients with anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (AAV).
Su-Fang Chen   +18 more
doaj   +1 more source

C1q A08 Is a Half-Cryptic Epitope of Anti-C1q A08 Antibodies in Lupus Nephritis and Important for the Activation of Complement Classical Pathway

open access: yesFrontiers in Immunology, 2020
To investigate the fine epitope(s) of anti-C1q A08 antibodies and their roles in complement activation in lupus nephritis, C1q A08 and related peptides with various amino acid sequences around A08 were synthesized.
Wen-Jun Wu   +23 more
doaj   +1 more source

Attention to renal involvement: report of 17 Joubert syndrome cases in children of a single center in China

open access: yesBMC Pediatrics, 2022
Background Joubert Syndrome (JS) is a rare genetic developmental disorder. We are aiming for increasing awareness of this disease especially kidney involvement in children with JS. Methods Clinical and genetic data of 17 cases of JS in Beijing children’s
Liang Ying   +5 more
doaj   +1 more source

Complement Activation Is Associated With Crescents in IgA Nephropathy

open access: yesFrontiers in Immunology, 2021
IntroductionCrescents, especially those found at a percentage greater than 50%, are often associated with rapid progression of kidney disease in IgA nephropathy (IgAN). The mechanism of crescents forming in IgAN is still unclear.
Zi Wang   +23 more
doaj   +1 more source

Progressive renal disease: Role of race and antihypertensive medications [PDF]

open access: yes, 1935
Progressive renal disease: Role of race and antihypertensive medications. Hypertension is associated with an accelerated rate of decline in renal function in patients with chronic renal disease. To identify factors that might alter the rate of decline in
Peter C. Brazy   +27 more
core   +1 more source

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