We demonstrate that Foxp1± mice, modeling FOXP1 haploinsufficiency, exhibit behavioral deficits, striatal neuroinflammatory changes including altered microglial complexity and synaptic pruning, and markedly reduced Pde10a expression. Pde10a inhibition starting immediately after birth restores Foxp1± behavior, microglial morphology, and pruning ...
Henning Fröhlich+8 more
wiley +1 more source
Cation-exchange chromatography of guanidine derivatives in plasma of patients with chronic renal failure. [PDF]
Guido O. Pérez+3 more
openalex +1 more source
Single‐Cell RNA Sequencing Delineates Renal Anti‐Fibrotic Mechanisms Mediated by TRPC6 Inhibition
Single‐cell transcriptomics reveals how TRPC6 inhibition alters renal cell composition and gene expression in CKD. The study uncovers a novel endothelial subpopulation (ECRIN), highlights key inflammatory and fibrotic pathways, and identifies a Prnp‐driven network linked to fibrosis resolution, offering mechanistic insight into TRPC6 as a potential ...
Yao Xu+12 more
wiley +1 more source
Retracted: Changes of Intestinal Flora and Lymphocyte Subsets in Patients with Chronic Renal Failure. [PDF]
And Alternative Medicine EC.
europepmc +1 more source
Early Sympathetic Activation in the Initial Clinical Stages of Chronic Renal Failure
G. Grassi+7 more
semanticscholar +1 more source
Research Progress on Biomaterials with Immunomodulatory Effects in Bone Regeneration
This review highlights recent advanced in immunomodulatory biomaterials for bone repair, focusing on design strategies, immune interactions, and clinical potential. Abstract The immune system plays a pivotal role in bone regeneration, and biomaterials engineered to modulate immune responses present a promising strategy for the treatment of extensive ...
Jianan Li+11 more
wiley +1 more source
Pulmonary Metastatic Calcifications Secondary to Chronic Renal Failure. [PDF]
Patil C+4 more
europepmc +1 more source
Restless legs syndrome in chronic renal failure patients on dialysis. [PDF]
van Tonder CB, Joubert G, Moodley A.
europepmc +1 more source
THE HAEMODYNAMIC RESPONSE TO CHRONIC RENAL FAILURE AS STUDIED IN THE AZOTAEMIC STATE
J. W. Mostert+5 more
openalex +1 more source
Preliminary observations on the elimination of acebutolol in severe chronic renal failure [letter]. [PDF]
C M Kaye, J. Dufton
openalex +1 more source