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IgE as a predictor to omalizumab response in patients with chronic spontaneous urticaria

Frontiers in Allergy
This multicenter study aimed to explore whether baseline total immunoglobulin E (IgE) levels could predict omalizumab response in chronic spontaneous urticaria (CSU) patients.
L. Ensina   +8 more
semanticscholar   +1 more source

Chronic spontaneous urticaria is not an allergic disease

European Journal of Dermatology, 2011
The links between chronic urticaria, IgE sensitization and allergy have been much discussed but little studied. We investigated IgE sensitization and allergy in 128 adult chronic urticaria patients during 2006-2008. During a one-day hospitalisation, the patients answered a standardized questionnaire and underwent blood serum analysis, physical tests ...
Frédéric, Augey   +5 more
openaire   +2 more sources

Omalizumab dosing patterns and drug survival in adult patients with chronic spontaneous urticaria

Journal of the European Academy of Dermatology and Venereology
Omalizumab is an effective treatment for chronic spontaneous urticaria (CSU), but strategies and predictors for guiding long‐term management and discontinuation remain limited.
D. G. Zhang   +9 more
semanticscholar   +1 more source

PTGS2: A potential immune regulator and therapeutic target for chronic spontaneous urticaria.

Life Science
AIMS Chronic spontaneous urticaria (CSU) is a common and debilitating skin disease that is difficult to control with existing treatments, and the pathogenesis of CSU has not been fully revealed.
Yihui Chen   +8 more
semanticscholar   +1 more source

Biomarkers to predict therapeutic response in chronic spontaneous urticaria: a review.

EJD. European journal of dermatology
Chronic spontaneous urticaria (CSU) is a relatively common dermatological disorder characterized by sudden and unpredictable onset of pruritic wheals and/or angioedema, for more than six weeks.
A. Giménez-Arnau, A. Salman, I. Podder
semanticscholar   +1 more source

Management of Chronic Spontaneous Urticaria in the Elderly

Drugs & Aging, 2015
The guidelines for the management of urticaria in adults and children have been revised and updated recently. However, there are few data in the literature concerning several aspects of this disease in the elderly (e.g., epidemiology, etiopathogenesis, clinical aspects, association with co-morbidities, efficacy and safety profiles of treatments, and ...
VENTURA, Maria Teresa   +5 more
openaire   +3 more sources

Chronic spontaneous urticaria remission definition and therapy stepping-down. WAO Position Paper.

Journal of Allergy and Clinical Immunology
BACKGROUND There is no global agreement on the definition of Chronic Spontaneous Urticaria (CSU) remission. OBJECTIVE To generate a consensus for clinical definitions in CSU focused on remission. METHODS The World Allergy Organization (WAO) Urticaria
J. Sánchez   +12 more
semanticscholar   +1 more source

Total IgE as a biomarker of omalizumab response in chronic spontaneous urticaria: A meta-analysis.

Allergy and Asthma Proceedings
Background: Omalizumab is approved for the treatment of chronic spontaneous urticaria (CSU) that is refractory to antihistamines. Total immunoglobulin E (IgE) levels have emerged as a possible biomarker to predict response to omalizumab.
Levi Keller   +5 more
semanticscholar   +1 more source

The future of targeted therapy in chronic spontaneous urticaria.

Annals of Allergy, Asthma & Immunology
Chronic urticaria can be divided into two subsets: chronic spontaneous urticaria (CSU) with skin lesions occurring without a specific trigger and chronic inducible urticaria (CIndU) which has an identified specific stimulus.
T. Min, S. Saini
semanticscholar   +1 more source

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