Results 1 to 10 of about 46,763 (166)

A clinical case of secondary xanthomatosis in a patient with biliary cirrhosis

open access: yesЛечащий Врач, 2021
The article describes the clinical manifestations of secondary xanthomatosis in a 46-year-old patient with primary biliary cirrhosis who was consulted by a dermatovenerologist.
N. V. Zilberberg   +7 more
doaj   +1 more source

Metabolic changes of Interleukin-12/15/18-stimulated human NK cells

open access: yesScientific Reports, 2021
Natural Killer (NK) cells acquire memory-like properties following a brief stimulation with IL-12, IL-15 and IL-18. These IL-12/15/18-preactivated NK cells, also known as cytokine-induced memory-like (CIML) NK cells, have been revealed as a powerful tool
Iñigo Terrén   +5 more
doaj   +1 more source

Increased expression of the immunoproteasome subunits PSMB8 and PSMB9 by cancer cells correlate with better outcomes for triple-negative breast cancers

open access: yesScientific Reports, 2023
Proteasome dependency is a feature of many cancers that can be targeted by proteasome inhibitors. For some cancer types, notably breast cancer and triple-negative breast cancer (TNBC), high mRNA expression of a modified form of the proteasome, called the
Karen Geoffroy   +4 more
doaj   +1 more source

COPD immunopathology [PDF]

open access: yesSeminars in Immunopathology, 2016
The immunopathology of chronic obstructive pulmonary disease (COPD) is based on the innate and adaptive inflammatory immune responses to the chronic inhalation of cigarette smoking. In the last quarter of the century, the analysis of specimens obtained from the lower airways of COPD patients compared with those from a control group of age-matched ...
CARAMORI, Gaetano   +5 more
openaire   +3 more sources

Type I interferon regulates proteolysis by macrophages to prevent immunopathology following viral infection.

open access: yesPLoS Pathogens, 2022
The ability to treat severe viral infections is limited by our understanding of the mechanisms behind virus-induced immunopathology. While the role of type I interferons (IFNs) in early control of viral replication is clear, less is known about how IFNs ...
Amanda J Lee   +21 more
doaj   +1 more source

Experience of therapy of psoriasis patients with methotrexate in the form of subcutaneous and intramuscularly injections

open access: yesЛечащий Врач, 2021
Psoriasis is one of the most common chronic dermatoses. About 125 million patients with this disease are registered in the world, and the frequency of occurrence in the structure of dermatological diseases is about 40%.
N. V. Zilberberg   +3 more
doaj   +1 more source

Immunopathology of uveitis [PDF]

open access: yesBritish Journal of Ophthalmology, 1998
Using conventional histological (light and electron microscopic examinations), immunohistological (immunofluorescent and immunoperoxidase), and molecular histological (in situ hybridisation and polymerase chain reaction (PCR) in situ hybridisation) techniques, the immunopathology of uveitis has been studied using inflamed ocular tissue.1-4 The findings
C C, Chan, Q, Li
openaire   +2 more sources

Immunopathology of schistosomiasis [PDF]

open access: yesImmunology & Cell Biology, 2006
Waterborne parasitic diseases plague tropical regions of the world with the development of water resources often increasing transmission. Skin‐penetrating cercariae (infectious stages of schistosome parasites) mature within their mammalian host, form sexual pairs and produce several hundred eggs per day.
Mark S, Wilson   +5 more
openaire   +2 more sources

Cytokine-Induced Memory-Like NK Cells: From the Basics to Clinical Applications

open access: yesFrontiers in Immunology, 2022
Natural killer (NK) cells are lymphocytes with a key role in the defense against viral infections and tumor cells. Although NK cells are classified as innate lymphoid cells (ILCs), under certain circumstances they exhibit adaptive and memory-like ...
Iñigo Terrén   +6 more
doaj   +1 more source

Primary cutaneous CD4+ pleomorphic small to medium cell T cell lymphoma: a clinical case

open access: yesЛечащий Врач, 2021
The diagnosis of primary cutaneous CD4+ pleomorphic T-cell lymphoma of the skin from small and medium-sized cells is difficult due to the rare occurrence of this nosology.
N. V. Zilberberg   +5 more
doaj   +1 more source

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