Results 121 to 130 of about 2,423,192 (204)

Colorectal Cancer: Epidemiology, Risk Factors, Signaling Pathways, Clinical Features, Screening, Diagnosis, and Management

MedComm, Volume 7, Issue 10, October 2026.
Colorectal cancer is a heterogeneous, adaptive disease shaped by population‐level risk, genomic and epigenetic alterations, tumor ecosystem evolution, and treatment pressure. This review integrates epidemiology, risk factors, signaling networks, clinical presentation, screening, molecular diagnosis, and stage‐ and biomarker‐guided management while ...
Kairui Wan, Ke Tang, Linglong Wang, Qin Tian, Mingwei Zheng, Cheng Qian, Limei Liu   +6 more
wiley   +1 more source

Pulmonary Arterial Hypertension Associated With Chronic Mephedrone Use: A Case Report

Pulmonary Circulation, Volume 16, Issue 4, October 2026.
ABSTRACT Mephedrone is a synthetic cathinone with sympathomimetic effects, but has not previously been linked to pulmonary arterial hypertension (PAH). We report a 42‐year‐old woman with no prior cardiopulmonary disease who presented with severe pre‐capillary PAH after a decade of near‐daily mephedrone use.
Masoud Kashoub, Michael Plunkett, Heba Nashat, Konstantinos Dimopoulos, Colm McCabe, Carl Harries, S. John Wort, Paul I. Dargan, Laura C. Price   +8 more
wiley   +1 more source

Pulmonary thromboendarterectomy after treatment with treprostenil in a chronic thromboembolic pulmonary hypertension patient: a case report

International Journal of General Medicine, 2011
Konstantinos Porpodis1, Maria Konoglou2, Paul Zarogoulidis1, Evangelos Kaimakamis2, Theodoros Kontakiotis1, Despoina Papakosta1, Vasilis Zervas1, Nikolaos Katsikogiannis3, Nikolaos Courcoutsakis4, Alexandros Mitrakas5, Panagiotis Touzopoulos5, Michael ...
Porpodis K, Konoglou M, Zarogoulidis P, Kaimakamis E, Kontakiotis T, Papakosta D, Zervas V, Katsikogiannis N, Courcoutsakis N, Mitrakas A, Touzopoulos P, Karanikas M, Zarogoulidis K, Markopoulou A   +13 more
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Unilateral Pulmonary Artery Lesion in an Immunocompromised Patient

Respirology Case Reports, Volume 14, Issue 10, October 2026.
We report a case of a unilateral septic pulmonary artery thrombus presenting as pulmonary infarction and pulmonary hypertension in an immunocompromised host. ABSTRACT We report a 62‐year‐old man with myelodysplastic syndrome on immunosuppressive therapy who presented with right lung consolidation and neutropenia. Despite broad antimicrobial therapy for
Seunghoon Lee, Kyung Soo Lee, Dong Young Jeong, Boram Lee, Junghee Lee, Dong Seop Jeong, Sung‐A Chang, Sun Hye Shin   +7 more
wiley   +1 more source

Diagnosis and management of chronic thromboembolic pulmonary hypertension (CTEPH) in sickle cell disease: A review

Pulmonary Circulation
Pulmonary hypertension in sickle cell disease (SCD) is a complex phenomenon resulting from multiple overlapping etiologies, including pulmonary vasoconstriction in the setting of chronic hemolytic anemia, diastolic dysfunction, and chronic thromboembolic
Kadija Hersi, Gautam V. Ramani, Jennie Y. Law, Ahmed S. Sadek, Anjali Vaidya, Mark T. Gladwin, Steven J. Cassady   +6 more
doaj   +1 more source

Chronic thromboembolic pulmonary hypertension

, 2019
Chronic thromboembolic pulmonary hypertension (CTEPH) is a complication of pulmonary embolism and a major cause of chronic PH leading to right heart failure and death. Lung ventilation/perfusion scintigraphy is the screening test of choice; a normal scan
Ghofrani, Hossein-Ardeschir, Delcroix, Marion, Matsubara, Hiromi, Ogo, Takeshi, Tapson, Victor F., Madani, Michael M., Jais, Xavier, Kim, Nick H., Mayer, Eckhard, Jenkins, David P.   +9 more
core   +1 more source

Is There a Difference in Occurrence of Complications Between Adults With Hemoglobin SS and Hemoglobin SC Disease: An Extended Systematic Review

European Journal of Haematology, Volume 117, Issue 4, Page 824-837, October 2026.
ABSTRACT Sickle cell disease (SCD) is characterized by both acute and chronic complications. The clinical manifestation of these complications differs between genotypes. Given the large amount of research already published, this systematic review aims to offer a complete overview of types of sickle cell complications between adults in the most common ...
Martijn van der Meer, Kim Velsink, Wing H. Tong, Jan W. Schoones   +3 more
wiley   +1 more source

Selective IL‐23 Inhibition in Conventional Treatment‐Refractory Pyoderma Gangrenosum: A Multicenter, Retrospective Study

International Journal of Dermatology, Volume 65, Issue 10, Page 2055-2065, October 2026.
The clinical effects of selective IL‐23 inhibition in refractory pyoderma gangrenosum, highlighting progressive ulcer healing, reduction in inflammation and pain, and steroid‐sparing effect, supporting the role of the IL‐23/Th17 axis as a therapeutic target.
Luca Bettolini, Carlo Alberto Maronese, Federica Derlino, Giovanni Genovese, Chiara Moltrasio, Luisa Sarno, Stefano Buffon, Bianca Cei, Giammarco Granieri, Valentina Dini, Marco Romanelli, Vincenzo Maione, Stefano Bighetti, Marina Venturini, Edoardo Cammarata, Paola Savoia, Antonio Di Guardo, Luigi Gargiulo, Ruggero Cascio Ingurgio, Antonio Costanzo, Lorenza Burzi, Claudia Leporati, Nunzia Di Cristo, Nicola Zerbinati, Alex G. Ortega‐Loayza, Angelo Valerio Marzano   +25 more
wiley   +1 more source

Effect of pulmonary endarterectomy for chronic thromboembolic pulmonary hypertension on stroke volume response to exercise

, 2014
In pulmonary hypertension, exercise is limited by an impaired right ventricular (RV) stroke volume response. We hypothesized that improvement in exercise capacity after pulmonary endarterectomy (PEA) for chronic thromboembolic pulmonary hypertension ...
Marcus, J. Tim, Surie, Sulaiman, Kind, Taco, Kloek, J.J., Bresser, P., van der Plas, M.N., Marcus, J.T., Vonk-Noordegraaf, Anton, Bresser, Paul, Surie, S., Kloek, Jaap J., van der Plas, Mart N., Kind, T., Vonk-Noordegraaf, A.   +13 more
core   +1 more source

Pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension: pathophysiology

European Respiratory Review, 2010
Pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH) are two of the key subgroups of pulmonary hypertension. They are characterised by different risk factors.
M. Humbert
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