Results 11 to 20 of about 47,816 (225)

Riociguat for the treatment of chronic thromboembolic pulmonary hypertension. [PDF]

New England Journal of Medicine, 2013
BACKGROUND: Riociguat, a member of a new class of compounds (soluble guanylate cyclase stimulators), has been shown in previous clinical studies to be beneficial in the treatment of chronic thromboembolic pulmonary hypertension. METHODS: In this phase 3,
CHEST-1 Study Group,, D'Armini, AM, Fritsch, A, Ghofrani, HA, Grimminger, F, Hoeper, MM, Jansa, P, Kim, NH, Mayer, E, Neuser, D, Simonneau, G, Wang, C, Weimann, G, Wilkins, MR   +13 more
core   +3 more sources

Chronic Thromboembolic Pulmonary Hypertension [PDF]

Seminars in Thrombosis and Hemostasis, 2006
Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare disease that results from obstruction of the major pulmonary arteries by incompletely resolved or organized pulmonary emboli that have become incorporated into the pulmonary artery wall, eventually causing an increase in pulmonary vascular resistance.
D'ARMINI, ANDREA MARIA, Piovella F., Barone M., Tapson V. F.   +3 more
exaly   +9 more sources

Optimizing the diagnosis and assessment of chronic thromboembolic pulmonary hypertension with advancing imaging modalities

Pulmonary Circulation, 2021
Imaging is key to nearly all aspects of chronic thromboembolic pulmonary hypertension including management for screening, assessing eligibility for pulmonary endarterectomy, and post-operative follow-up. While ventilation/perfusion scintigraphy, the gold
Seth Kligerman, Albert Hsiao
doaj   +1 more source

Plasma metabolomic profile in chronic thromboembolic pulmonary hypertension

Pulmonary Circulation, 2020
We aimed to characterize the plasma metabolome of chronic thromboembolic pulmonary hypertension patients using a high-throughput unbiased omics approach.
Gustavo A. Heresi, Jacob T. Mey, John R. Bartholomew, Ihab S. Haddadin, Adriano R. Tonelli, Raed A. Dweik, John P. Kirwan, Satish C. Kalhan   +7 more
doaj   +1 more source

Case Report: Successful Concomitant Pulmonary Thromboendarterectomy and Carotid Endarterectomy

Frontiers in Cardiovascular Medicine, 2022
Pulmonary thromboendarterectomy is the treatment of choice for chronic thromboembolic pulmonary hypertension. Pulmonary thromboendarterectomy concomitant with additional cardiac procedures was reported as safe and feasible.
Zhan Liu, Zhan Liu, Xiaopeng Liu, Xia Zheng, Fan Lin, Guang Sun, Zhidong Ye, Yanan Zhen, Peng Liu, Peng Liu   +9 more
doaj   +1 more source

Effect of riociguat on pulmonary arterial compliance in the PATENT and CHEST studies

Pulmonary Circulation, 2020
Pulmonary arterial compliance is a measure of the pulsatile afterload of the right ventricle. Lower pulmonary arterial compliance is associated with reduced right ventricular function and worse prognosis in pulmonary hypertension. The effect of pulmonary
Thenappan Thenappan, Nadine Al-Naamani, Stefano Ghio, Hossein-Ardeschir Ghofrani, Paul M. Hassoun, Marc Pritzker, Adam Torbicki, Sylvia Nikkho, Dennis Busse, Ioana R. Preston   +9 more
doaj   +1 more source

Central Extracorporeal Membrane Oxygenation and Early Rehabilitation for Persistent Severe Pulmonary Hypertension Following Pulmonary Endarterectomy [PDF]

Acute and Critical Care, 2019
Chronic thromboembolic pulmonary hypertension is potentially curable with a pulmonary endarterectomy. However, approximately 20% of patients have persistent pulmonary hypertension after pulmonary endarterectomy, which is a major risk factor for ...
Gil Myeong Seong, Sang-Bum Hong, Jin Won Huh, Chae-Man Lim, Younsuck Koh, Jae Won Lee, Sung-Ho Jung, Duck-Woo Park, Jae Seung Lee   +8 more
doaj   +1 more source

Evaluation of code-based algorithms to identify pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension patients in large administrative databases

Pulmonary Circulation, 2020
Large administrative healthcare (including insurance claims) databases are used for various retrospective real-world evidence studies. However, in pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension, identifying patients ...
Viviane P. Sprecher, Eva-Maria Didden, Joel N. Swerdel, Audrey Muller   +3 more
doaj   +1 more source

Pulmonary Endarterectomy in Patients with Antiphospholipid Syndrome-Associated Chronic Thromboembolic Pulmonary Hypertension

Anatolian Journal of Cardiology, 2022
Background: Antiphospholipid syndrome is an autoimmune disease characterized by the occurrence of venous and/or arterial thrombosis. Chronic thromboembolism is one of the known established pathogenesis of pulmonary hypertension, known as chronic ...
Serpil Taş, Arzu Antal, Ali Fuad Durusoy, Mehmed Yanartaş, Kübra Yıldız, Sehnaz Olgun Yıldızeli, Derya Kocakaya, Bülent Mutlu, Fatma Alibaz-öner, Haner Direskeneli, Nevsun İnanç, Atakan Erkılınç, Bedrettin Yıldızeli   +12 more
doaj   +1 more source

Respiratory rate modulation improves symptoms in patients with pulmonary hypertension

SAGE Open Medicine, 2021
Background: Pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension are chronic diseases with a severe symptom burden. Common symptoms are dyspnoea at light activity and general fatigue that limits daily activities.
Barbro Kjellström, Bodil Ivarsson, Lise-Lotte Landenfelt Gestré, Henrik Ryftenius, Magnus Nisell   +4 more
doaj   +1 more source