Results 61 to 70 of about 1,222 (146)

Update on Chronic Thromboembolic Pulmonary Hypertension [PDF]

Circulation, 2014
Chronic thromboembolic pulmonary hypertension (CTEPH) is a distinct pulmonary vascular disease caused by chronic obstruction of major pulmonary arteries that is amenable to cure by pulmonary endarterectomy (PEA). Main features of CTEPH as opposed to pulmonary arterial hypertension (PAH) are a nonhomogeneous distribution of disease in segments of the ...
Irene Marthe, Lang, Michael, Madani
openaire   +2 more sources

Renal‐vascular axis: unmasking its role in vascular endothelial growth factor‐inhibitor vascular toxicity in cancer patients

British Journal of Pharmacology, EarlyView.
Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley   +1 more source

Familial Chronic Thromboembolic Pulmonary Hypertension [PDF]

Chest, 2016
Chronic thromboembolic pulmonary hypertension (CTEPH) is an uncommon disease that is the most serious complication associated with unresolved pulmonary embolism. This disease has several risk factors, but no familial pattern has been described. Few thrombophilic conditions have been reported to increase risk of CTEPH, and none of the hereditary ...
Julianna, Desmarais, C Gregory, Elliott
openaire   +2 more sources

Cardiotoxicity of BRAF/MEK inhibitors

British Journal of Pharmacology, EarlyView.
Abstract Rapidly accelerated fibrosarcoma type B/B‐Raf proto‐oncogene, serine/threonine kinase (BRAF) and mitogen‐activated protein kinase (MEK) inhibitors have transformed outcomes in cancer therapy, particularly in melanoma. However, cardiovascular toxicities are increasingly recognized in real‐world clinical practice.
Katharina Seuthe, Valerie Lohner, Kevin Terre, Thomas Riffelmacher, Roman Pfister   +4 more
wiley   +1 more source

Pulmonary hypertension in patients with chronic myeloproliferative disorders

European Respiratory Review, 2015
Pulmonary hypertension (PH) is a major complication of several haematological disorders. Chronic myeloproliferative diseases (CMPDs) associated with pulmonary hypertension have been included in group five of the clinical classification for pulmonary ...
Yochai Adir, Davide Elia, Sergio Harari
doaj   +1 more source

The burden of COVID‐19 in hospitalized people with diabetes mellitus in Brazil: Insights from four years of the pandemic

Diabetic Medicine, EarlyView.
Abstract Aims Coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), is more severe in people with diabetes mellitus due to immune dysfunction, exacerbated inflammation and increased risk of co‐morbidities and mortality.
Taís Mendes Camargo, Bianca Aparecida Siqueira, Luiz Felipe Azevedo Marques, Lucas Silva Mello, Fernando Augusto Lima Marson   +4 more
wiley   +1 more source

Case Report: Dangerous liaisons between splenectomy and eltrombopag-induced chronic thromboembolic pulmonary hypertension in patients with immune thrombocytopenia: report of two cases and review of the literature

Frontiers in Cardiovascular Medicine
IntroductionPrimary immune thrombocytopenia is an autoimmune bleeding disorder characterized by variable immune-mediated platelet destruction. These patients have reported thrombotic complications, both venous and arterial, in addition to bleeding ...
Roberto Castelli, Enrico Atzori, Alessandro Palmerio Delitala, Salvatore Antonio Masala, Valentina Micheluzzi, Enrico Ponti, Enrico Ponti, Giuseppe Sanna, Dante Castro, Antonio Gidaro, Mattia Donadoni, Roberto Manetti, Pierluigi Merella, Nicia Isabella Profili, Andrea Maria D'Armini, Gavino Casu, Gavino Casu   +16 more
doaj   +1 more source

Is There a Difference in Occurrence of Complications Between Adults With Hemoglobin SS and Hemoglobin SC Disease: An Extended Systematic Review

European Journal of Haematology, EarlyView.
ABSTRACT Sickle cell disease (SCD) is characterized by both acute and chronic complications. The clinical manifestation of these complications differs between genotypes. Given the large amount of research already published, this systematic review aims to offer a complete overview of types of sickle cell complications between adults in the most common ...
Martijn van der Meer, Kim Velsink, Wing H. Tong, Jan W. Schoones   +3 more
wiley   +1 more source

Chronic thromboembolic pulmonary hypertension: approaches to diagnosis and treatment

Медицинский совет, 2013
The article tells about incidence of pulmonary hypertension after pulmonary artery thromboembolia; congenital and acquired coagulation abnormalities in patients with venous thromboembolism; potential factors of chronic thromboembolic pulmonary ...
N. A. Shostak, A. A. Klimenko, N. A. Demidova, S. M. Sorokoletov, K. V. Razumov, N. M. Babadaeva   +5 more
doaj   +1 more source

Pulmonary endarterectomy in chronic thromboembolic pulmonary hypertension

Turkish Journal of Thoracic and Cardiovascular Surgery, 2013
Background: This study aims to assess the early results of pulmonary endarterectomy. Methods: Between March 2011 and July 2012, 64 patients (29 males, 35 females; mean age 47.4 +/- 10.4 years; range 14 to 78 years) who underwent pulmonary endarterectomy were retrospectively analyzed.
Sakarya Üniversitesi/Tıp Fakültesi/Cerrahi Tıp Bilimleri Bölümü, Hasan Sunar, Bedrettin Yildizeli, Serpi Tas, Mehmet Yanartas, Saçlı, Hakan, Mahmut Kis, Burcin Cayhan, Tuncer Kocak, Cihangir Kaymaz, Saçlı, Hakan   +10 more
openaire   +3 more sources