Association of immune response with efficacy and safety outcomes in adults with phenylketonuria administered pegvaliase in phase 3 clinical trials [PDF]
, 2018 Background: This study assessed the immunogenicity of pegvaliase (recombinant Anabaena variabilis phenylalanine [Phe] ammonia lyase [PAL] conjugated with polyethylene glycol [PEG]) treatment in adults with phenylketonuria (PKU) and its impact on safety ...
Atkinson, John P +14 more
core +2 more sources
Chronic urticaria treatment patterns and changes in quality of life: AWARE study 2-year results
The World Allergy Organization Journal, 2020 Background A Worldwide Antihistamine-Refractory Chronic Urticaria (CU) patient Evaluation (AWARE) is a non-interventional, multicenter study including patients from Europe, Central and Latin America, Asia-Pacific, and the Middle East.
M. Maurer +5 more
semanticscholar +1 more source
Chronic spontaneous urticaria: Focus on pathophysiology to unlock treatment advances
Allergy. European Journal of Allergy and Clinical Immunology, 2022 Chronic spontaneous urticaria (CSU) is a debilitating skin disease characterized by intensely itchy wheals, angioedema, or both. Symptoms recur spontaneously, on a near‐daily basis, over >6 weeks; many patients experience flare‐ups over several years and,
A. Kaplan +5 more
semanticscholar +1 more source
WAO guideline for the management of hereditary angioedema [PDF]
, 2012 Hereditary Angioedema (HAE) is a rare disease and for this reason proper diagnosis and appropriate therapy are often unknown or not available for physicians and other health care providers.
Aygören-Pürsün, Emel +17 more
core +1 more source
Clinical Therapeutics, 2020 PURPOSE It has been observed that certain patients with chronic spontaneous or idiopathic urticaria (CSU/CIU) have a personal history of a significant stressor before urticaria onset, while the prevalence of any psychopathology among these patients is ...
G. Konstantinou, G. Konstantinou
semanticscholar +1 more source
Etiology of chronic urticaria: the Ecuadorian experience [PDF]
, 2018 Background: The purpose of this study was to identify chronic urticaria (CU) etiologies and treatment modalities in Ecuador. We propose that the sample distribution fits the expected one, and that there is an association between the etiology and its ...
Cano, J. +9 more
core +1 more source
The Role of Crosstalk of Immune Cells in Pathogenesis of Chronic Spontaneous Urticaria
Frontiers in Immunology, 2022 Chronic spontaneous urticaria (CSU) is defined as recurrent episodes of spontaneous wheal development and/or angioedema for more than six weeks and at least twice a week.
Bin Zhou +4 more
semanticscholar +1 more source
The Results of Autologous Skin Test in Patients with Chronic Urticaria in Hamadan, Iran
Electronic Physician, 2016 Introduction: The etiology of chronic urticaria is unknown in many cases. In this study, we demonstrated the presence of autoimmune antibodies in patients with chronic urticaria by using of the Autologous Serum Skin Test (ASST).
Mojgan Safari, Hooshyar Sayemiri
doaj +1 more source
Urticaria and mimickers of urticaria
Frontiers in Allergy, 2023 Urticaria is a common skin condition encountered across various specialties in medicine, especially in dermatology and allergy/immunology practice. It has a heterogeneous presentation hence it is unsurprising that many skin conditions may be confused ...
Jie Shen Fok +4 more
doaj +1 more source
Association of extraintestinal manifestations of inflammatory bowel disease in a province of western Hungary with disease phenotype: Results of a 25-year follow-up study [PDF]
, 2003 AIM: IBD is a systemic disease associated with a large number of extraintestinal manifestations (EIMs). Our aim was to determine the prevalence of EIMs in a large IBD cohort in Veszprem Province in a 25-year follow-up study.
Balogh, Zsuzsanna +6 more
core +1 more source