Results 51 to 60 of about 3,068,792 (354)

Dupilumab in patients with chronic spontaneous urticaria (LIBERTY-CSU CUPID): two randomized, double-blind, placebo-controlled, phase 3 trials.

Journal of Allergy and Clinical Immunology
BACKGROUND Chronic spontaneous urticaria (CSU) is a chronic inflammatory disease characterized by recurrent pruritic wheals (hives) and/or angioedema. Patients with CSU could remain symptomatic despite standard-of-care H1-antihistamines (H1-AH) or anti ...
Marcus Maurer, T. Casale, Sarbjit S. Saini, M. Ben-Shoshan, A. Giménez-Arnau, J. Bernstein, Akiko Yagami, Aleksandra Stjepanovic, A. Radin, H. Staudinger, Naimish Patel, N. Amin, B. Akinlade, C. Fan, Deborah Bauer, G. Yancopoulos, K. Patel, L. Mannent, E. Laws   +18 more
semanticscholar   +1 more source

Chronic urticaria and thyroid pathology

The World Allergy Organization Journal, 2020
Urticaria is defined as the sudden appearance of erythematous, itchy wheals of variable size, with or without angioedema (AE) (swelling of the deeper layers of the skin). Its classification depends on time course of symptoms and the presence of eliciting
S. González-Díaz, M. Sánchez-Borges, Diana Maria Rangel-Gonzalez, R. Guzmán-Avilán, J. Canseco-Villarreal, A. Arias-Cruz   +5 more
semanticscholar   +1 more source

Basophils in Chronic Urticaria [PDF]

Journal of Investigative Dermatology Symposium Proceedings, 2001
Blood basophils are reduced in chronic urticaria and respond less well to immunologic stimuli. Active recruitment of basophils from peripheral blood into lesional skin may be important in wheal pathogenesis.
openaire   +2 more sources

Psychiatric comorbidity in chronic urticaria patients: a systematic review and meta-analysis

Clinical and Translational Allergy, 2019
BackgroundDermatological illness can affect the quality of life and may coexist with psychiatric disorders.ObjectiveThe aim of this review was to systematically evaluate the published evidence of any psychiatric disorders that may coexist with chronic ...
G. Konstantinou, G. Konstantinou
semanticscholar   +1 more source

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients With Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

Arthritis Care &Research, EarlyView.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; ClinicalTrials.gov identifier ...
Hermine I. Brunner, Jordi Antón, Inmaculada Calvo‐Penadés, Richard Dimelow, Gerd Horneff, Sylvia Kamphuis, Rebecca Marino, Andre van Maurik, Kirsten Minden, Masaaki Mori, Josephine Ocran‐Appiah, Christel Wilkinson, Yuichi Yamasaki, Deepak Assudani, for the Pediatric Rheumatology Collaborative Study Group (PRCSG) and Paediatric Rheumatology International Trials Organisation (PRINTO) Network investigators   +14 more
wiley   +1 more source

Physical Exercise Improves Symptomatic Dermographism

Clinical and Translational Allergy
Background Short‐term exercise may reduce disease activity in symptomatic dermographism (SD), but its prevalence and short‐ and long‐term effects remain unclear and understudied.
Ragıp Ertaş, Muhammed Burak Yücel, Murat Türk, Şule Ketenci Ertaş, Emek Kocatürk, Melba Muñoz   +5 more
doaj   +1 more source

Evaluation of lipid profiles in patients with chronic spontaneous urticaria: A case-control study

Медицинская иммунология
Chronic urticaria is referred to recurrent, pruritic, erythematous, and edematous mucocutaneous lesions on most days of the week, and persists for six weeks or more.
Abbas Khalili, Fatemeh Azadi Talab Davoudabadi, Bamdad Sadeghi   +2 more
doaj   +1 more source

Infection focus as a potential cause of chronic urticaria – a case of a 12-year-old boy and the review of literature

Pediatria i Medycyna Rodzinna, 2019
Chronic urticaria is a rare disease in the paediatric population. It is characterised by the presence of blebs, angioedema or the coexistence of these changes for a period of more than 6 weeks.
Anna Góra, Majka Jaszczura, Małgorzata Morawiecka-Pietrzak, Edyta Machura   +3 more
doaj   +1 more source

Further Analyses of the Safety of Verubecestat in the Phase 3 EPOCH Trial of Mild-To-Moderate Alzheimer’s Disease [PDF]

, 2019
Background: Verubecestat, a BACE1 inhibitor that reduces Aβ levels in the cerebrospinal fluid of humans, was not effective in a phase 3 trial (EPOCH) of mild-to-moderate AD and was associated with adverse events.
Aisen, Paul S., Cummings, Jeffrey L., Egan, Michael F., Furtek, Christine, Kost, James, Lines, Christopher, Mahoney, Erin, Michaelson, David, Mukai, Yuki, Stone, Julie, Tariot, Pierre N., Vellas, Bruno, Voss, Tiffini   +12 more
core   +3 more sources

Zafirlukast: Chronic Urticaria [PDF]

Hospital Pharmacy, 2015
This Hospital Pharmacy feature is extracted from Off-Label Drug Facts, a publication available from Wolters Kluwer Health. Off-Label Drug Facts is a practitioner-oriented resource for information about specific drug uses that are unapproved by the US Food and Drug Administration. This new guide to the literature enables the health care professional or
Joyce A, Generali, Dennis J, Cada
openaire   +2 more sources