Results 71 to 80 of about 2,763,581 (350)

Fenebrutinib in H1 antihistamine-refractory chronic spontaneous urticaria: a randomized phase 2 trial

Nature Medicine, 2021
Bruton’s tyrosine kinase (BTK) is crucial for FcεRI-mediated mast cell activation and essential for autoantibody production by B cells in chronic spontaneous urticaria (CSU).
M. Metz, G. Sussman, R. Gagnon, P. Staubach, Tonny Tanus, William H. Yang, Jeremy J. Lim, H. J. Clarke, J. Galanter, L. Chinn, Tom Chu, A. Teterina, T. Burgess, D. Haddon, Timothy T Lu, M. Maurer   +15 more
semanticscholar   +1 more source

Incubating Ideas: A Typology of Design Thinking Academic Centers in American Higher Education

New Directions for Higher Education, EarlyView.
ABSTRACT Twenty years after the founding of the Hasso–Plattner Institute of Design (the d.School) at Stanford University, a wide range of academic centers and institutes have been established to prioritize innovation, creativity, and design thinking. This qualitative study presents a typology of these centers across the United States, drawing on “About
Margaret T. Konkel
wiley   +1 more source

Estudo da qualidade de vida nos pacientes com urticária crônica Quality of life assessment in patients with chronic urticaria

Anais Brasileiros de Dermatologia, 2011
FUNDAMENTOS: A urticária crônica compromete o doente por interferir nas atividades diárias, prejudicar a autoestima e as relações interpessoais. Os profissionais de saúde subestimam seu impacto na qualidade de vida dos doentes.
Ana Paula Fusel de Ue, Patrícia Karla de Souza, Osmar Rotta, Wellington de Jesus Furlani, Amanda Rodrigues Miranda de Lima, Dominique Sanda Oliveira Vilarinho Sabbag   +5 more
doaj   +1 more source

Omalizumab rapidly improves angioedema‐related quality of life in adult patients with chronic spontaneous urticaria: X‐ACT study data [PDF]

, 2018
Background: The X‐ACT study aimed to examine the effect of omalizumab treatment on quality of life (QoL) in chronic spontaneous urticaria (CSU) patients with angioedema refractory to high doses of H1‐antihistamines. Methods: In X‐ACT, a phase III, double‐
Barbosa, Bernstein, Bork, Brooks, Choi, Finlay, Finlay, Grattan, Hallak, Herguner, James, Kaplan, Krieger, Maurer, Maurer, Maurer, McCormack, Metz, Metz, Saini, Saini, Shikiar, Staubach, Staubach, Weller, Weller, Weller, Zazzali, Zhao, Zuberbier   +29 more
core   +1 more source

Cetuximab Hypersensitivity in the Setting of Asymptomatic Alpha‐Gal Sensitization

Head &Neck, EarlyView.
ABSTRACT Background Alpha‐gal syndrome is an allergic condition resulting from the bite of the Lonestar tick in the southeastern US that leads to sensitization to mammalian products containing the oligosaccharide galactose‐alpha‐1,3‐galactose (alpha‐gal).
Alexander G. Emerson, Lindsay Mundy, Barbara A. Murphy, Cosby A. Stone   +3 more
wiley   +1 more source

Autoimmune Diseases Are Linked to Type IIb Autoimmune Chronic Spontaneous Urticaria

Allergy Asthma and Immunology Research, 2021
Purpose Patients with chronic spontaneous urticaria (CSU) have an increased risk for comorbid autoimmune diseases. In this retrospective multicenter study of CSU patients, we evaluated clinical and laboratory features of CSU associated with a higher risk
P. Kolkhir, S. Altrichter, R. Asero, A. Daschner, M. Ferrer, Ana M. Giménez-Arnau, T. Hawro, T. Jakob, T. Kinaciyan, A. Kromminga, G. Konstantinou, M. Makris, M. Metz, P. Skov, P. Staubach, G. Sussman, Ke-jun Zhang, M. Maurer   +17 more
semanticscholar   +1 more source

Recovery from symptoms using an extensively hydrolyzed formula with synbiotic in infants with presumed cow's milk allergy

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objective Extensively hydrolyzed formulas (eHF) are the first‐line approach for cow's milk protein allergy (CMPA). This study evaluated the effects of eHF with synbiotic eHF (SeHF) on the general condition and symptoms of presumed CMPA infants during the initial 4‐week exclusion diet period.
Anaïs Lemoine, Florence Villard‐Truc, Imene Ait Mohamed Amar, François Payot   +3 more
wiley   +1 more source

Evaluation of anxiety in children diagnosed with chronic urticaria

Medicine Science
This study aimed to evaluate anxiety levels in children diagnosed with chronic urticaria and to compare them with those in a healthy control group. Designed as a cross-sectional study, it included children aged 9–18 years diagnosed with chronic urticaria
Ugur Altas, Halil Alkaya, Seda Cevik, Mehmetcan Sezer, Firat Oz, Zeynep Meva Altas, Mehmet Yasar Ozkars   +6 more
doaj   +1 more source

Differential Diagnoses of Systemic Mastocytosis in Routinely Processed Bone Marrow Biopsy Specimens: A Review [PDF]

, 2010
Diagnosis of systemic mastocytosis (SM) is mainly based on the morphological demonstration of compact mast cell infiltrates in various tissue sites. In almost all patients such infiltrates are detected in the bone marrow.
Horny, H. -P., Sotlar, K., Valent, P.
core   +1 more source

Effect of cow's milk protein allergy during infancy on eating behavior at 4 years of age: A cohort study

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives This study aimed to investigate the eating behaviors of preschool children who had been exposed to a restricted diet due to an oral food challenge‐confirmed diagnosis of cow's milk protein allergy (CMPA) during early infancy. Methods This prospective cohort study compared the eating behaviors of Brazilian children previously ...
Anne Jardim‐Botelho, Marcela Barros Barbosa de Oliveira, Jackeline Motta‐Franco, Tatiane Graça Martins, Sarah Cristina Fontes Vieira, Ikaro Daniel de Carvalho Barreto, Aline Vieira Bezerra, Ricardo Queiroz Gurgel   +7 more
wiley   +1 more source