Results 101 to 110 of about 226,860 (310)

Natural history study of recessive dystrophic epidermolysis bullosa wounds and patient reported outcomes using mobile application home photography

Scientific Reports
Recessive dystrophic epidermolysis bullosa (RDEB) is a rare, blistering genetic disease where wounding and wound pain are the most reported problems by patients.
Shivali Fulchand, Jaron Nazaroff, Nicki Harris, Jodi Y. So, Ricardo Villanueva Gaona, Estephannie Alvarez, Shufeng Li, Ying Lu, Edward Eid, Jean Y. Tang   +9 more
doaj   +1 more source

Calciphylaxis as A Rare Cause of A Chronic Wound in An 83-Year-Old Woman

Geriatrics, 2019
Chronic wounds are common in elderly patients, and the majority of them are caused by vascular diseases, such as peripheral arterial occlusive disease (PAD) or chronic venous insufficiency.
Stefan Dörr, Gregor Weisser, Ralf Lobmann   +2 more
doaj   +1 more source

The effect of OTR4120, a heparan sulfate glycosaminoglycan memetic on improving acute and impaired wound healing in rats [PDF]

, 2012
__Abstract__ Dating back to the prehistoric times, wounds have been common with mankind. The treatment of wounds is an art as old as humanity. Today, wounds are of increasing concern in our society in terms of their prevalence and costs.
Tong, M. (Miao)
core   +1 more source

Biofilm is a major virulence determinant in bacterial colonization of chronic skin ulcers independently from the multidrug resistant phenotype [PDF]

, 2017
Bacterial biofilm is a major factor in delayed wound healing and high levels of biofilm production have been repeatedly described in multidrug resistant organisms (MDROs).
Bordignon, Valentina, Cavallo, Ilaria, Cilli, Laura, De Santis, Alessandra, Di Domenico, Enea Gino, Di Salvo, Fabiola, Ensoli, Fabrizio, Farulla, Ilaria, Gallo, Maria Teresa, La Parola, Ilaria Lesnoni, Pimpinelli, Fulvia, Pontone, Martina, Prignano, Grazia, Sperduti, Isabella, Toma, Luigi, Vespaziani, Matteo   +15 more
core   +2 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Results of hyperbaric oxygenation in chronic wound healing – preliminary findings

Studia Medyczne, 2016
Introduction: Improved wound healing decreases the risk of complications, increases the possibilities of further treatment, rehabilitation, and care, and improves the quality of life for the patients. Aim of the research: The aim of this paper is to
Piotr Dzięgielewski, Emilia Mikołajewska, Aleksander Goch   +2 more
doaj   +1 more source

Multi-function based modeling of 3D heterogeneous wound scaffolds for improved wound healing [PDF]

, 2010
This paper presents a new multi-function based modeling of 3D heterogeneous porous wound scaffolds to improve wound healing process for complex deep acute or chronic wounds.
Koc, Bahattin, Koç, Bahattin, Ozbolat, Ibrahim T., Özbolat, İbrahim T.   +3 more
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

NASA Light Emitting Diode Medical Applications from Deep Space to Deep Sea [PDF]

, 2001
This work is supported and managed through the NASA Marshall Space Flight Center-SBIR Program. LED-technology developed for NASA plant growth experiments in space shows promise for delivering light deep into tissues of the body to promote wound healing ...
Buchmann, Ellen V., Caviness, James, Cevenini, Vita, Chen, Gina, Cwiklinski, Joan, Gould, Lisa J., Hodgson, Brian D., Ignatius, Ron, Kane, Mary P., Martin, Todd, Meyer, Glenn A., Stinson, Helen, Turner, Scott G., Whelan, Harry T., Whelan, Noel T.   +14 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source