Results 31 to 40 of about 237,116 (358)
Increased Levels of BAMBI Inhibit Canonical TGF-β Signaling in Chronic Wound Tissues
Cells, 2023 Chronic wounds affect more than 2% of the population worldwide, with a significant burden on affected individuals, healthcare systems, and societies. A key regulator of the entire wound healing cascade is transforming growth factor beta (TGF-β), which ...
Sabrina Ehnert +10 more
doaj +1 more source
Dialkylcarbamoyl chloride (DACC)-coated dressings in the management and prevention of wound infection: A systematic review [PDF]
, 2017 Objective: Dialkylcarbomoyl chloride (DACC)-coated dressings (Leukomed Sorbact and Cutimed Sorbact) irreversibly bind bacteria at the wound surface that are then removed when the dressing is changed.
Bua, N. +6 more
core +2 more sources
A novel model of chronic wounds: importance of redox imbalance and biofilm-forming bacteria for establishment of chronicity. [PDF]
PLoS ONE, 2014 Chronic wounds have a large impact on health, affecting ∼6.5 M people and costing ∼$25B/year in the US alone. We previously discovered that a genetically modified mouse model displays impaired healing similar to problematic wounds in humans and that ...
Sandeep Dhall +13 more
doaj +1 more source
Biofilm and Equine Limb Wounds
Animals, 2021 In chronic wounds in humans, biofilm formation and wound chronicity are linked, as biofilms contribute to chronic inflammation and delayed healing. Biofilms are aggregates of bacteria, and living as biofilms is the default mode of bacterial life; within ...
Elin Jørgensen +2 more
doaj +1 more source
Wound dressings: curbing inflammation in chronic wound healing [PDF]
Emerging Topics in Life Sciences, 2021 Chronic wounds represent an economic burden to healthcare systems worldwide and a societal burden to patients, deeply impacting their quality of life. The incidence of recalcitrant wounds has been steadily increasing since the population more susceptible, the elderly and diabetic, are rapidly growing. Chronic wounds are characterised by a delayed wound
Davide Vincenzo Verdolino +3 more
openaire +3 more sources
Albanian Journal of Trauma and Emergency Surgery, 2019 Chronic wounds represent an enormous health, social and economic burden in modern society. With the increasing incidence of diabetes and obesity as well as the ageing of the population, we correspondingly expect a rise in the incidence of chronic wounds.
Skender Veliu +2 more
doaj +1 more source
Multifunctional hydrogels for chronic wounds repairing
Biosurface and Biotribology, 2023 Because of their tissue‐like mechanical performances, high biocompatibility, and adjustable functionality, hydrogels have become increasingly attractive materials for promoting wound healing.
Xiao Wang, Rong Hu, Lu Han, Xiong Lu
doaj +1 more source
Tumescent Injections in Subcutaneous Pig Tissue Disperse Fluids Volumetrically and Maintain Elevated Local Concentrations of Additives for Several Hours, Suggesting a Treatment for Drug Resistant Wounds. [PDF]
, 2020 PurposeBolus injection of fluid into subcutaneous tissue results in accumulation of fluid at the injection site. The fluid does not form a pool. Rather, the injection pressure forces the interstitial matrix to expand to accommodate the excess fluid in ...
Dunn, James CY +5 more
core +2 more sources
Journal of Infection in Developing Countries, 2015 Introduction: Chronic wounds represent a major health burden worldwide. It has been hypothesized that the polymicrobial nature of wounds plays an important role in their healing process. Thus, a review of pathogen frequency and susceptibility patterns in
Shin Yee Wong +2 more
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2020 Diabetics chronic wounds are characterized by high levels of oxidative stress (OS) and are often colonized by biofilm-forming bacteria that severely compromise healing and can result in amputation.
Jane H. Kim +7 more
doaj +1 more source