Results 11 to 20 of about 102,681 (262)
Nature Reviews Disease Primers, 2022 Chronic wounds are characterized by their inability to heal within an expected time frame and have emerged as an increasingly important clinical problem over the past several decades, owing to their increasing incidence and greater recognition of associated morbidity and socio-economic burden.
Vincent Falanga +7 more
openaire +5 more sources
Inflammation in Chronic Wounds [PDF]
International Journal of Molecular Sciences, 2016 Non-healing chronic wounds present a major biological, psychological, social, and financial burden on both individual patients and the broader health system. Pathologically extensive inflammation plays a major role in the disruption of the normal healing cascade.
Ruilong Zhao +4 more
openaire +2 more sources
Nutrition and Chronic Wounds [PDF]
Advances in Wound Care, 2014 Significance: Nutrition is one of the most basic of medical issues and is often ignored as a problem in the management of our chronic wound patients. Unfortunately, malnutrition is widespread in our geriatric patients even in nursing homes in developed countries.
Molnar, Joseph Andrew +2 more
openaire +3 more sources
Surgical Clinics of North America, 1997 Skin ulcers are the most common chronic wounds. Current management principles and theories of causation of the most common ulcers--pressure, diabetic, and venous--are described. Issues related to occlusive dressings, compression dressings, topical antimicrobials, debridement, growth factors, grafting, and bioengineered tissue therapy are discussed ...
W H, Eaglstein, V, Falanga
openaire +2 more sources
Functional Biomaterials for Treatment of Chronic Wound
Frontiers in Bioengineering and Biotechnology, 2020 The increasing number of patients with chronic wounds caused by diseases, such as diabetes, malignant tumors, infections, and vasculopathy, has caused severe economic and social burdens.
Xi Zhang +7 more
doaj +1 more source
Increased Levels of BAMBI Inhibit Canonical TGF-β Signaling in Chronic Wound Tissues
Cells, 2023 Chronic wounds affect more than 2% of the population worldwide, with a significant burden on affected individuals, healthcare systems, and societies. A key regulator of the entire wound healing cascade is transforming growth factor beta (TGF-β), which ...
Sabrina Ehnert +10 more
doaj +1 more source
A novel model of chronic wounds: importance of redox imbalance and biofilm-forming bacteria for establishment of chronicity. [PDF]
PLoS ONE, 2014 Chronic wounds have a large impact on health, affecting ∼6.5 M people and costing ∼$25B/year in the US alone. We previously discovered that a genetically modified mouse model displays impaired healing similar to problematic wounds in humans and that ...
Sandeep Dhall +13 more
doaj +1 more source
Biofilm and Equine Limb Wounds
Animals, 2021 In chronic wounds in humans, biofilm formation and wound chronicity are linked, as biofilms contribute to chronic inflammation and delayed healing. Biofilms are aggregates of bacteria, and living as biofilms is the default mode of bacterial life; within ...
Elin Jørgensen +2 more
doaj +1 more source
Wound dressings: curbing inflammation in chronic wound healing [PDF]
Emerging Topics in Life Sciences, 2021 Chronic wounds represent an economic burden to healthcare systems worldwide and a societal burden to patients, deeply impacting their quality of life. The incidence of recalcitrant wounds has been steadily increasing since the population more susceptible, the elderly and diabetic, are rapidly growing. Chronic wounds are characterised by a delayed wound
Davide Vincenzo Verdolino +3 more
openaire +3 more sources
Albanian Journal of Trauma and Emergency Surgery, 2019 Chronic wounds represent an enormous health, social and economic burden in modern society. With the increasing incidence of diabetes and obesity as well as the ageing of the population, we correspondingly expect a rise in the incidence of chronic wounds.
Skender Veliu +2 more
doaj +1 more source