Results 31 to 40 of about 9,135 (208)

Chronobiology of Epilepsy [PDF]

open access: yesNature Precedings, 2008
AbstractA fine balance between neuronal excitation and inhibition governs the physiological state of the brain. It has been hypothesized that when this balance is lost as a result of excessive excitation or reduced inhibition, pathological states such as epilepsy emerge. Decades of investigation have shown this to be true in vitro.
Sachin S. Talathi   +6 more
openaire   +2 more sources

Differential impact in young and older individuals of blue-enriched white light on circadian physiology and alertness during sustained wakefulness

open access: yesScientific Reports, 2017
We tested the effect of different lights as a countermeasure against sleep-loss decrements in alertness, melatonin and cortisol profile, skin temperature and wrist motor activity in healthy young and older volunteers under extendend wakefulness. 26 young
Virginie Gabel   +8 more
doaj   +1 more source

Circadian cuisine in synchronizing holistic nutrition and biological rhythms

open access: yesWorld Nutrition
Chronobiology is an emerging area of research exploring the complex relationship between circadian rhythms and nutrition. This review discusses the interplay of chronobiology and overall nutrition. In simpler terms, the time we eat affects our nutrition
Amna Mughal   +5 more
doaj   +1 more source

A circadian clock regulates efflux by the blood-brain barrier in mice and human cells

open access: yesNature Communications, 2021
The blood-brain barrier is critical for neural function. Here, the authors show that efflux of xenobiotics through the BBB follows a circadian rhythm in mice and human cells.
Shirley L. Zhang   +6 more
doaj   +1 more source

Weight loss in conservative treatment of obesity in women is associated with physical activity and circadian phenotype: a longitudinal observational study

open access: yesBioPsychoSocial Medicine, 2019
Introduction The study investigates the association between circadian phenotype (CP), its stability (interdaily stability - IS) and physical activity (PA) in a weight loss (WL) programme.
Eva Fárková   +8 more
doaj   +1 more source

Vision at high latitudes: High sensitivity without specific boreal adaptations in photoreception in reindeer (Rangifer tarandus L.)

open access: yesFunctional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract The light climate at high latitudes, in particular the extended twilight of winter and the reduced diel variation in light level in midsummer and midwinter, potentially constrains visual function and the synchronisation of temporal organisation in polar species. In this
Nicholas J. C. Tyler   +3 more
wiley   +1 more source

Neuronal Responses to Short Wavelength Light Deficiency in the Rat Subcortical Visual System

open access: yesFrontiers in Neuroscience, 2021
The amount and spectral composition of light changes considerably during the day, with dawn and dusk being the most crucial moments when light is within the mesopic range and short wavelength enriched.
Patrycja Orlowska-Feuer   +5 more
doaj   +1 more source

The Pro‐Apoptotic Effect of Glucose Restriction in NSCLC via AMPK‐Regulated Circadian Clock Gene Bmal1

open access: yesCancer Science, EarlyView.
In this study we investigate the role of the core circadian gene BMAL1 in regulating mechanisms within non‐small cell lung cancer cells, revealing that circadian rhythm disruption may represent another significant factor triggering apoptosis. ABSTRACT The circadian clock is a crucial regulator of mammalian physiology, controlling daily oscillations in ...
Tao Wei   +5 more
wiley   +1 more source

Light color importance for circadian entrainment in a diurnal (Octodon degus) and a nocturnal (Rattus norvegicus) rodent

open access: yesScientific Reports, 2017
The central circadian pacemaker (Suprachiasmatic Nuclei, SCN) maintains the phase relationship with the external world thanks to the light/dark cycle. Light intensity, spectra, and timing are important for SCN synchronisation.
Maria Angeles Bonmati-Carrion   +3 more
doaj   +1 more source

Hypoglycemic timeslots after hospital discharge in patients with diabetes on multiple daily insulin injection: Dose of Insulin CHanged According to the Reported Glucose by Libre Pro (DISCHARGe study)

open access: yesJournal of Diabetes Investigation, EarlyView.
The frequency and severity of hypoglycemia peak before lunch and its nadir is 17:30 PM and increases through the post‐discharge days. ABSTRACT Introduction Insulin improves clinical outcomes in hospitalized patients; however, hypoglycemia hinders discharge transition in patients with insulin‐treated diabetes.
Manabu Saito   +5 more
wiley   +1 more source

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