Results 31 to 40 of about 7,125,299 (256)

A Study on the Lubrication Characteristics and Parameter Influence of a High-Speed Train Herringbone Gearbox

open access: yesLubricants
To investigate the lubrication characteristics in high-speed train gearboxes, a two-stage herringbone gearbox with an idle gear was analyzed. The lubricant flow and distribution were shown using the moving particle semi-implicit (MPS) method.
Shuai Shao   +6 more
doaj   +1 more source

Lubrication mechanism in gearbox of high-speed railway trains

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2020
In this study, the moving particle semi-implicit (MPS) method is employed for numerical simulation of flow field in gearbox of high-speed railway trains so as to understand the lubrication mechanism and mode in the gearbox during high-speed operation.
Xingqiao DENG   +7 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Large-scale security constrained optimal reactive power flow for operational loss management on the GB electricity transmission network [PDF]

open access: yes, 2010
This thesis was submitted for the degree of Engineering Doctorate and awarded by Brunel University, 22/12/2010.The transmission of power across the GB transmission system, as operated by National Grid, results in inevitable loss of electrical power ...
Macfie, Peter
core   +7 more sources

Thermal Performance Evaluation in Gas Turbine Aero Engines Accessory Gearbox

open access: yesInternational Journal of Turbomachinery, Propulsion and Power, 2020
This paper presents a methodological approach for mathematical modelling and physics-based analysis of accessory gearbox (AGB) thermal behavior in gas turbine aero engines. The AGB structure, as one of the main sources of heat in gas turbine aero engines,
Soheil Jafari   +2 more
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

Analytical and Experimental Investigation of Windage–Churning Behavior in Spur, Bevel, and Face Gears

open access: yesApplied Sciences
This paper presents comparable sets of the no-load power loss as a product of windage and churning behaviors of a family of various rotating parts (i.e., disc, spur gear, straight bevel gear, and orthogonal face gear).
Yu Dai, Caihua Yang, He Liu, Xiang Zhu
doaj   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Investigation of the Churning Loss Reduction in 2D Motion-Converting Mechanisms

open access: yes, 2021
In recent years, two dimensional (2D) hydraulic components have significantly flourished. After a brief development introduction of the 2D pump and 2D flowmeter, it could be concluded that the churning loss, which is caused by the rotational motion of 2D
Yu Huang   +3 more
core   +1 more source

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani   +10 more
wiley   +1 more source

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