Results 21 to 30 of about 33,318 (283)
The Chylomicron: Relationship to Atherosclerosis [PDF]
International Journal of Vascular Medicine, 2012 The B-containing lipoproteins are the transporters of cholesterol, and the evidence suggests that the apo B48-containing postprandial chylomicron particles and the triglyceride-rich very low density lipoprotein (VLDL) particles play an important part in the development of the plaque both directly and indirectly by their impact on LDL composition.
Gerald H. Tomkin, Daphne Owens
openaire +4 more sources
Comparison of the metabolism of chylomicrons and chylomicron remnants by the perfused liver [PDF]
Biochemical Journal, 1978 1. The hepatic metabolism of chylomicrons and chylomicron remnants was compared after adding approximately equal numbers of each lipoprotein particle to the perfusate of isolated livers. 2. At least 40% of the added remnants were metabolized by the liver compared with less than 3% for chylomicrons. 3.
P A Mayes, R S Gardner
openaire +3 more sources
Moderate exercise increases affinity of large very low density lipoproteins for hydrolysis by lipoprotein lipase [PDF]
, 2015 Context: Postprandial triglyceride (TG) concentration is independently associated with cardiovascular disease risk. Exercise reduces postprandial TG concentrations but the mechanisms responsible are unclear.
Bedford, Dorothy K. +5 more
core +1 more source
Journal of Lipid Research, 1997 The size of cholesterol-rich lipoprotein particles is a strong determinant of whether they may be deposited in the arterial wall and by this become potentially atherogenic. This study deals with the in vivo transformation of larger-sized chylomicrons and chylomicron remnants to smaller-sized remnants. Twelve healthy men aged 22 to 45 years were given a
Karpe, F +3 more
openaire +5 more sources
Alterations of intestinal lipoprotein metabolism in diabetes mellitus and metabolic syndrome [PDF]
, 2015 Diabetes and metabolic syndrome are associated with abnormal postprandial lipoprotein metabolism, with a significant delay in the clearance of many lipid parameters, including triglycerides and chylomicrons.
ARCA, Marcello
core +1 more source
Journal of Internal Medicine, 2019 Renewed interest in triglyceride‐rich lipoproteins as causative agents in cardiovascular disease mandates further exploration of the integrated metabolism of chylomicrons and very low‐density lipoproteins (VLDL).
Elias Björnson +14 more
semanticscholar +1 more source
Secretion-recapture process of apolipoprotein E in hepatic uptake of chylomicron remnants in transgenic mice [PDF]
, 1994 To investigate the role of apoE in hepatic uptake of chylomicron remnants, we studied chylomicron metabolism in transgenic mice overexpressing apoE in the liver.
Gotoda T +10 more
core +1 more source
Chylomicrons stimulate incretin secretion in mouse and human cells
Diabetologia, 2017 Aims/hypothesisLipids are a potent stimulus for the secretion of glucagon-like peptide (GLP)-1 and glucose-dependent insulinotropic peptide (GIP). Traditionally, this effect was thought to involve the sensing of lipid digestion products by free fatty ...
A. Psichas +4 more
semanticscholar +1 more source
Deficient Cholesterol Esterification in Plasma of apoc2 Knockout Zebrafish and Familial Chylomicronemia Patients. [PDF]
, 2017 Hypertriglyceridemia is an independent risk factor for cardiovascular disease. Apolipoprotein C-II (APOC2) is an obligatory cofactor for lipoprotein lipase (LPL), the major enzyme catalyzing plasma triglyceride hydrolysis.
Gaudet, Daniel +2 more
core +1 more source
VEGFR-3 signaling regulates triglyceride retention and absorption in the intestine [PDF]
, 2018 The lymphatic system transports dietary lipids absorbed and packaged as chylomicrons by enterocytes, for delivery to the bloodstream. Once considered a passive drainage, chylomicron entry into intestinal lymphatic vessels, or lacteals, is now emerging to
Cifarelli, Vincenza +2 more
core +2 more sources