Results 11 to 20 of about 14,363 (185)

Apolipoprotein F is reduced in humans with steatosis and controls plasma triglyceride‐rich lipoprotein metabolism

Hepatology, EarlyView., 2022
Hepatic APOF transcript levels correlate inversely with plasma TG and hepatic steatosis in humans. ApoF expression in mice promotes VLDL‐TG production and lipoprotein remnant clearance in mice. Abstract Background NAFLD affects nearly 25% of the global population. Cardiovascular disease (CVD) is the most common cause of death among patients with NAFLD,
Audrey Deprince, Nathalie Hennuyer, Sander Kooijman, Amanda C. M. Pronk, Eric Baugé, Viktor Lienard, An Verrijken, Eveline Dirinck, Luisa Vonghia, Eloïse Woitrain, Niels J. Kloosterhuis, Eléonore Marez, Pauline Jacquemain, Justina C. Wolters, Fanny Lalloyer, Delphine Eberlé, Sandrine Quemener, Emmanuelle Vallez, Anne Tailleux, Mostafa Kouach, Jean‐Francois Goossens, Violeta Raverdy, Bruno Derudas, Jan Albert Kuivenhoven, Mikaël Croyal, Bart van de Sluis, Sven Francque, François Pattou, Patrick C. N. Rensen, Bart Staels, Joel T. Haas   +30 more
wiley   +1 more source

Electron microscopic studies of the assembly, intracellular transport, and secretion of chylomicrons by rat intestine

Journal of Lipid Research, 1977
A detailed ultrastructural investigation of the assembly, intracellular transport, and secretion of chylomicrons by rat proximal jejunal intestinal cells was performed in rats fed corn oil.
S M Sabesin, S Frase
doaj   +1 more source

Chylomicron protein content and the rate of lipoprotein lipase activity

Journal of Lipid Research, 1976
Chylomicrons isolated from rat intestinal lymph were incubated with plasma. Protein transfer to chylomicrons, reaction rate with purified lipoprotein lipase, and content of lipase cofactor were determined.
C J Fielding, P E Fielding
doaj   +1 more source

Plasma clearance and liver uptake of chylomicron remnants generated by hepatic lipase lipolysis: evidence for a lactoferrin-sensitive and apolipoprotein E-independent pathway

Journal of Lipid Research, 1999
Chylomicrons labeled with [3H]cholesterol and [14C]triglyceride fatty acids were lipolyzed by hepatic lipase (HL) in vitro and then injected intravenously into normal mice fed low- or high-fat diets, and into apolipoprotein (apo) E-deficient mice.
Susan E. Crawford, Jayme Borensztajn
doaj   +1 more source

Size and lipid composition of chylomicrons of different Svedberg units of flotation

Journal of Lipid Research, 1970
Chylomicrons from thoracic duct lymph of rabbits which were fed corn oil were separated in a preparative ultracentrifuge into subfractions of different S(f) values in order to compare their size, as determined by electron microscopy, with that expected ...
R. Fraser
doaj   +1 more source

Forces involved in chylomicron binding by isolated cells of rat liver

Journal of Lipid Research, 1967
The binding of chylomicrons by isolated liver cells has been found to decrease as temperature increases. It is greatest at the isoelectric point of the chylomicrons; although it occurs both above and below this pH, it decreases most rapidly as the pH is ...
Joan A. Higgins
doaj   +1 more source

Retention of lipolytic products in chylomicrons incubated with lipoprotein lipase: electron microscope study

Journal of Lipid Research, 1976
Early effects of lipolysis on the structure of chylomicrons in vitro were studied in rat chylomicrons incubated with purified bovine mild lipoprotein lipase at pH 8.1. The amount of the albumin added to the incubation medium was limited so that freefatty
E J Blanchette-Mackie, R O Scow
doaj   +1 more source

Composition of proteins of mesenteric lymph chylomicrons in the rat and alterations produced upon exposure of chylomicrons to blood serum and serum proteins.

Journal of Lipid Research, 1978
Protein composition was determined in mesenteric lymph chylomicrons from fat-fed rats. Among the proteins of intermediate molecular weight, apoproteins A-I and the arginine-rich apoprotein accounted for 31% and 4% of the total protein mass, respectively.
K Imaizumi, M Fainaru, R J Havel
doaj   +1 more source

Cholesteryl esters in lymph chylomicrons: contribution from high density lipoprotein transferred from plasma into intestinal lymph

Journal of Lipid Research, 1993
Most of the cholesterol in intestinal chyle and chylomicrons is derived from plasma. Our aim was to determine how much plasma low density (LDL) and high density (HDL) lipoproteins contribute to the cholesterol in chyle and chylomicrons, and to examine ...
HC Oliveira, K Nilausen, H Meinertz, EC Quintão   +3 more
doaj   +1 more source

Behavior of dog lymph chylomicron lipid constituents during incubation with serum*

Journal of Lipid Research, 1963
Dog lymph chylomicrons incubated with serum showed a progressive gain in free cholesterol whereas no change took place in the cholesterol ester and triglyceride fractions.
O. Minari, D.B. Zilversmit
doaj   +1 more source