Results 41 to 50 of about 14,726 (218)

Association between remnant cholesterol and chronic kidney disease: Systematic review and meta‐analysis

Diabetes, Obesity and Metabolism, Volume 27, Issue 5, Page 2573-2583, May 2025.
Abstract Background and Aims Adequate lipid control has emerged as a key factor in the prevention and management of chronic kidney disease (CKD). Remnant cholesterol (RC), a lipoprotein with an established association with cardiovascular risk, has been investigated in the context of CKD.
Paschalis Karakasis, Dimitrios Patoulias, Manfredi Rizzo, Nikolaos Fragakis, Christos S. Mantzoros   +4 more
wiley   +1 more source

Forces involved in chylomicron binding by isolated cells of rat liver

Journal of Lipid Research, 1967
The binding of chylomicrons by isolated liver cells has been found to decrease as temperature increases. It is greatest at the isoelectric point of the chylomicrons; although it occurs both above and below this pH, it decreases most rapidly as the pH is ...
Joan A. Higgins
doaj  

Lung‐Specific mRNA Delivery by Ionizable Lipids with Defined Structure‐Function Relationship and Unique Protein Corona Feature

Advanced Science, Volume 12, Issue 14, April 10, 2025.
A novel structure‐function relationship is identified for lung‐targeting ionizable lipids with nonpermanent charges. These lipids feature N‐methyl and secondary amine groups in their heads and three tails derived from epoxyalkanes, demonstrating superior pulmonary selectivity and efficiency.
Xiaoyan He, Runyuan Wang, Yan Cao, Yan Ding, Yan Chang, Haoru Dong, Rong Xie, Guisheng Zhong, Huiying Yang, Jianfeng Li   +9 more
wiley   +1 more source

Behavior of dog lymph chylomicron lipid constituents during incubation with serum*

Journal of Lipid Research, 1963
Dog lymph chylomicrons incubated with serum showed a progressive gain in free cholesterol whereas no change took place in the cholesterol ester and triglyceride fractions.
O. Minari, D.B. Zilversmit
doaj  

The Role of Cholesterol Metabolism and Its Regulation in Tumor Development

Cancer Medicine, Volume 14, Issue 7, April 2025.
ABSTRACT Background Within the tumor microenvironment, tumor cells undergo metabolic reprogramming of cholesterol due to intrinsic cellular alterations and changes in the extracellular milieu. Furthermore, cholesterol reprogramming within this microenvironment influences the immune landscape of tumors, facilitating immune evasion and consequently ...
Yongmei Wu, Wenqian Song, Min Su, Jing He, Rong Hu, Youbo Zhao   +5 more
wiley   +1 more source

Cholesteryl esters in lymph chylomicrons: contribution from high density lipoprotein transferred from plasma into intestinal lymph

Journal of Lipid Research, 1993
Most of the cholesterol in intestinal chyle and chylomicrons is derived from plasma. Our aim was to determine how much plasma low density (LDL) and high density (HDL) lipoproteins contribute to the cholesterol in chyle and chylomicrons, and to examine ...
HC Oliveira, K Nilausen, H Meinertz, EC Quintão   +3 more
doaj  

Chemical Toxicants Used for Food Preservation in Africa. Is it a Case of Ignorance or Food Fraud? A Review

Health Science Reports, Volume 8, Issue 4, April 2025.
ABSTRACT Background and Aims This review examined the use of chemical preservatives in food preservation and the food fraud risks associated with its misuse in Africa. In Africa, there is growing reliance on the use of synthetic chemical preservation such as benzoates, nitrates or sorbates to preserve foods to improve the storage life of the foods ...
Nnabueze Darlington Nnaji, Helen Onyeaka, Kingsley Tochukwu Ughamba, Chukwuebuka Maxwell Ononugbo, Chinasa Valerie Olovo, Ifeanyi Michael Mazi   +5 more
wiley   +1 more source

Metabolism of chylomicrons by the isolated rat liver

Journal of Lipid Research, 1967
Isolated livers perfused with washed corn oil chylomicrons labeled in vivo with palmitic acid-1-14C removed a large proportion of the chylomicrons. Slices from these livers oxidized chylomicron fatty acid esters to both carbon dioxide and acetoacetate ...
Joseph A. Ontko, D.B. Zilversmit
doaj  

Binding of Selected Ligands to Human Protein Disulfide Isomerase and Microsomal Triglyceride Transfer Protein Complex and the Associated Conformational Changes: A Computational Molecular Modelling Study

ChemistryOpen, Volume 14, Issue 4, April 2025.
The interactions of MTP, MTPα and MTPβ (PDI) with three representative small‐molecule ligands are investigated using computational structural and chemical analysis to characterize the binding site structures, the binding strength, the key residues involved, and the conformational changes.
Yong Xiao Yang, Peng Li, Bao Ting Zhu
wiley   +1 more source

Inhibitory effects of C apolipoproteins from rats and humans on the uptake of triglyceride-rich lipoproteins and their remnants by the perfused rat liver.

Journal of Lipid Research, 1985
Like rat C apolipoproteins, each of the C apolipoproteins from human blood plasma (C-I, C-II, C-III-1, and C-III-2) bound to small chylomicrons from mesenteric lymph of estradiol-treated rats and inhibited their uptake by the isolated perfused rat liver.
E Windler, R J Havel
doaj