Results 51 to 60 of about 14,726 (218)
ABSTRACT Introduction Hereditary transthyretin amyloid polyneuropathy (ATTRv‐PN) is a rare and progressive neurodegenerative disorder characterized by axonal neuropathy and amyloid deposits. Early detection of disease onset and progression is crucial for timely therapeutic intervention.
Eva Sole Cruz+7 more
wiley +1 more source
The effect of saturated and unsaturated lipids on the composition of mesenteric lymph triglyceride-rich lipoproteins was studied in rats. A short-term steady-state infusion model was developed in mesenteric lymph fistula rats.
F Renner+3 more
doaj
OBJETIVO: Avaliar o efeito do captopril, sobre o metabolismo dos quilomícrons e de seus remanescentes e as possíveis alterações nas concentrações dos lípides plasmáticos em hipertensos e hipercolesterolêmicos.
Renato J. Alves+4 more
doaj +1 more source
ABSTRACT Background Hair loss disorders, including non‐cicatricial forms such as alopecia areata (AA) and androgenetic alopecia (AGA), as well as cicatricial forms, represent significant dermatological concerns influenced by various factors, including lipid metabolism.
Yuhan Xie+9 more
wiley +1 more source
ABSTRACT Aims Sitosterolemia, is a disorder of increased plant sterol levels leading to a variable presentation and haematological manifestations. Although considered rare, the prevalence is likely underestimated due to the variable phenotype and challenges in diagnosis. The delayed diagnosis may lead to cardiovascular complications.
Dilhara Gamage+4 more
wiley +1 more source
The surface coat of chylomicrons: electron microscopy
Electron microscope studies were performed on thoracic duct lymph and on washed chylomicrons from dogs fed corn oil. High-resolution electron micrographs showed the presence of a surface coat that differed from the core material and did not resemble a ...
M.M. Salpeter, D.B. Zilversmit
doaj
Role of PNPLA3 in Hepatic Stellate Cells and Hepatic Cellular Crosstalk
ABSTRACT Aims Since its discovery, the patatin‐like phospholipase domain containing 3 (PNPLA3) (rs738409 C>G p.I148M) variant has been studied extensively to unravel its molecular function. Although several studies proved a causal relationship between the PNPLA3 I148M variant and MASLD development and particularly fibrosis, the pathological mechanisms ...
Maria Castanho Martins+5 more
wiley +1 more source
The apoprotein composition of rat lymph chylomicrons and very low density lipoprotein (VLDL) was investigated following isolation and purification by preparative gel electrophoresis. The medium molecular weight apoproteins in the 27,000-60,000 range were
N H Fidge, P J McCullagh
doaj
Disentangling Organ‐Specific Roles of Farnesoid X Receptor in Bile Acid and Glucolipid Metabolism
ABSTRACT Background and Aims The farnesoid X receptor (FXR) is an attractive pharmaceutical target for metabolic dysfunction‐associated steatotic liver disease (MASLD). However, its tissue‐specific roles in energy metabolism remain controversial, hindering the development of effective therapies. To address this, new approaches are required.
Tingting Li+12 more
wiley +1 more source
The Role of Unesterified Fatty Acid Transport in Chylomicron Metabolism [PDF]
Donald S. Fredrickson+2 more
openalex +1 more source