Results 71 to 80 of about 33,318 (283)
Experimental Physiology, Volume 110, Issue 7, Page 936-948, 1 July 2025.Abstract In health, the liver is a metabolically flexible organ that plays a key role in regulating systemic lipid and glucose concentrations. There is a constant flux of fatty acids (FAs) to the liver from multiple sources, including adipose tissue, dietary, endogenously synthesized from non‐lipid precursors, intrahepatic lipid droplets and recycling ...
Kieran Smith +2 more
wiley +1 more source
Journal of Lipid Research, 1999 Chylomicrons labeled with [3H]cholesterol and [14C]triglyceride fatty acids were lipolyzed by hepatic lipase (HL) in vitro and then injected intravenously into normal mice fed low- or high-fat diets, and into apolipoprotein (apo) E-deficient mice.
Susan E. Crawford, Jayme Borensztajn
doaj
Lipid levels are inversely associated with infectious and all-cause mortality: international MONDO study results. [PDF]
, 2018 Cardiovascular (CV) events are increased 36-fold in patients with end-stage renal disease. However, randomized controlled trials to lower LDL cholesterol (LDL-C) and serum total cholesterol (TC) have not shown significant mortality improvements.
Canaud, Bernard +11 more
core +3 more sources
Food Science &Nutrition, Volume 13, Issue 6, June 2025.Omega‐3 fatty acids supplementation significantly reduced circulating levels of triglycerides (TG) (standardized mean difference [SMD] = −0.25, 95% confidence interval [CI] = −0.38 to −0.11) and total cholesterol (TC) (SMD = −0.12, 95% CI = −0.23 to −0.02), with no significant impact on the levels of high‐density lipoprotein cholesterol (HDL‐C), low ...
Chunyu Zhang +10 more
wiley +1 more source
Hypertriglyceridemia—Causes, Significance, and Approaches to Therapy
Frontiers in Endocrinology, 2020 Hypertriglyceridemia (HTG) is a common metabolic disorder with both genetic and lifestyle factors playing significant roles in its pathophysiology. HTG poses a risk for the development of cardiovascular disease (CVD) in the population at large and for ...
Leinys S. Santos-Baez, Henry N. Ginsberg
doaj +1 more source
The Effects of Dietary Food Fortified with Vitamin B4 on Lipid Profiles in Serum and Liver Tissue [PDF]
, 2010 The effects of dietary food fortified with vitamin B4 on lipid profiles in serum and liver tissue were studied. Rats were paired-fed a 0.25% vitamin B4 diet or a diet without vitamin B4 for 10 days.
Buang, Y. (Yohanes)
core
Unpacking and understanding the impact of proprotein convertase subtilisin/kexin type 9 inhibitors on apolipoprotein B metabolism [PDF]
, 2017 No abstract ...
Packard, Chris J.
core +1 more source
The Acidic Domain of GPIHBP1 Is Important for the Binding of Lipoprotein Lipase and Chylomicrons*
Journal of Biological Chemistry, 2008 GPIHBP1, a glycosylphosphatidylinositol-anchored endothelial cell protein of the lymphocyte antigen 6 (Ly6) family, plays a key role in the lipolysis of triglyceride-rich lipoproteins (e.g. chylomicrons). GPIHBP1 is expressed along the luminal surface of
P. Gin +8 more
semanticscholar +1 more source
Food Science &Nutrition, Volume 13, Issue 6, June 2025.In a 12‐week clinical trial, DAG reduced serum TG and LDL cholesterol in obese individuals. In high‐fat diet mice, DAG lowered lipids, visceral fat, and hepatic steatosis, acting via inhibiting lipid synthesis (SCD1, FASN) and promoting fatty acid oxidation (CPT‐1) while modulating glycerophospholipid metabolism.
Lina Shi +7 more
wiley +1 more source
Chylomicron protein content and the rate of lipoprotein lipase activity
Journal of Lipid Research, 1976 Chylomicrons isolated from rat intestinal lymph were incubated with plasma. Protein transfer to chylomicrons, reaction rate with purified lipoprotein lipase, and content of lipase cofactor were determined.
C J Fielding, P E Fielding
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