Results 81 to 90 of about 14,032 (176)

Monoclonal antibodies that bind to the Ly6 domain of GPIHBP1 abolish the binding of LPL

Journal of Lipid Research, 2017
GPIHBP1, an endothelial cell protein, binds LPL in the interstitial spaces and shuttles it to its site of action inside blood vessels. For years, studies of human GPIHBP1 have been hampered by an absence of useful antibodies.
Xuchen Hu, Mark W. Sleeman, Kazuya Miyashita, MacRae F. Linton, Christopher M. Allan, Cuiwen He, Mikael Larsson, Yiping Tu, Norma P. Sandoval, Rachel S. Jung, Alaleh Mapar, Tetsuo Machida, Masami Murakami, Katsuyuki Nakajima, Michael Ploug, Loren G. Fong, Stephen G. Young, Anne P. Beigneux   +17 more
doaj   +1 more source

The intracellular chylomicron highway: novel insights into chylomicron biosynthesis, trafficking, and secretion

Current Opinion in Lipidology
Purpose of review Chylomicron biosynthesis plays a vital role in supplying essential lipids and lipid soluble vitamins to peripheral tissues for various functions. Despite this, the intracellular synthesis, trafficking, and secretion of chylomicrons remains only partly understood.
Visser, Ankia, Hussain, M. Mahmood, Kuivenhoven, Jan Albert   +2 more
openaire   +3 more sources

From platelets to particles: Optimizing extracellular vesicle isolation in a National Blood Centre

Vox Sanguinis, Volume 121, Issue 3, Page 245-253, March 2026.
Abstract Background and Objectives Platelet‐derived extracellular vesicles (PEVs) are submicron, membrane‐bound particles released upon platelet activation, with a recognized role in haemostasis, inflammation and immunoregulation. PEVs remain insufficiently characterized in blood products.
Y. Chintala, A. Waters, F. McGrath, A. Lorusso, C. Wynne, S. Meaney   +5 more
wiley   +1 more source

The significance of lipoprotein lipase in rat skeletal muscles

Journal of Lipid Research, 1977
Lipoprotein lipase was assayed in extracts of acetone-ether powders of rat skeletal muscles. Enzyme activity in soleus had typical characteristics of lipoprotein lipase in other tissues: inhibition by molar NaCl and protamine sulfate and activation by ...
M H Tan, T Sata, R J Havel
doaj   +1 more source

[Chylomicron metabolism].

Revista do Hospital das Clinicas, 1990
The liver is known to play a central role in the chylomicron metabolism. It synthesizes apolipoproteins (e.g., apo A I, apo C II, apo E), lecithin cholesterol acyltransferase, hepatic lipase and is responsible for the chylomicron remnant removal. Not surprisingly then the chylomicron metabolism is compromised in liver diseases such as acute hepatitis ...
A O, Damião, A M, Sipahi e, E C, Quintão   +2 more
openaire   +1 more source

Hepatic uptake of chylomicron remnants

Journal of Lipid Research, 1997
Chylomicrons are formed in the intestine and transport dietary triglyceride to peripheral tissues and cholesterol to the liver. The enzyme lipoprotein lipase, with apolipoprotein (apo)C-II as a co-factor, hydrolyzes chylomicron triglyceride allowing the delivery of free fatty acids to muscle and adipose tissue.
openaire   +3 more sources

Non-remnant triglyceride-rich lipoproteins due to lipoprotein lipase deficiency increase atherosclerosis in mice. [PDF]

Nat Commun
Cabodevilla AG, Izquierdo MC, Basu D, Younis W, Tirumalasetty MB, Miao QR, Nasias D, Kanter JE, Ho TWW, Gjini J, Fisher E, Kim J, Lee WL, Bornfeldt K, Goldberg IJ.   +14 more
europepmc   +1 more source

Chylomicron metabolism

Journal of Biological Chemistry, 1989
M M Hussain, R W Mahley, J K Boyles, P A Lindquist, W J Brecht, T L Innerarity   +5 more
openaire   +1 more source

Evidence of interparticle chylomicron "bridging" in mouse mesenteric lymph after a lipid bolus. [PDF]

J Lipid Res
Neupane KR, Karakashian A, Liu M, Gordon SM.   +3 more
europepmc   +1 more source

Guide for Selecting Experimental Models to Study Dietary Fat Absorption. [PDF]

Nutrients
Nauli AM, Phan A, Mai K, Tran K, Nauli SM.   +4 more
europepmc   +1 more source