Results 111 to 120 of about 57,869 (249)

SPROUTS_DB: An Implemented Database of Contaminants for Extracellular Vesicle Proteomics Studies

PROTEOMICS, Volume 26, Issue 7, Page 69-83, July 2026.
ABSTRACT Current proteomics techniques allow rapid identification and quantification of proteins within any given biological source. However, LC–MS/MS proteomics is vulnerable to laboratory and sample‐associated contaminants. Therefore, accurate identification and annotation of such contaminants is crucial for development of reliable databases ...
Maria Gaetana Giovanna Pittalà, Loredana Leggio, Greta Paternò, Elena Giusto, Laura Civiero, Vincenzo Cunsolo, Silvia Vivarelli, Antonella Di Francesco, Emanuele Alpi, Nunzio Iraci, Rosaria Saletti   +10 more
wiley   +1 more source

Comparison of the Action of Chymotrypsin Alpha and Chymotrypsin B upon Several Protein Substrates

, 1951
Laskowski isolated in 1947 from beef pancreas a crystalline zymogen of a proteolytic enzyme. He demonstrated that this zymogen when activated was similar but not identical to chymotrypsin alpha. The crystalline activated form of this zymogen was obtained
Ambrose, John A.
core  

Effect of chymotrypsin on the urinary tract infections. [PDF]

, 1962
It is reported that the anti-inflammatory effect of c h ymotrypsin, a proteolytic enzyme, exceeded that of trypsin and paralleled that of prednisolone, and moreover chymotrypsin caused less untoward reactions than trypsin and prednisolone.
内藤, 政男, 三木, 信男, 近藤, 賢   +2 more
core  

Covalent and non-covalent interaction of chymotrypsin with α2-macroglobulin

, 1987
The pattern of covalent crosslinking between human α2-macroglobulin (α2M) and chymotrypsin has been investigated by chromatography and polyacrylamide gel electrophoresis in denaturing medium. Reaction with a single mol of chymotrypsin per mol α2M results
Delain, Etienne, Martine Tourbez, Favaudon, Vincent, François Pochon, Pochon, François, Tourbez, Martine, Etienne Delain, Vincent Favaudon   +7 more
core   +1 more source

Fecal Proteomics Suggest Potential Biomarkers for Non‐Alcoholic Fatty Liver Disease and Steatohepatitis

PROTEOMICS – Clinical Applications, Volume 20, Issue 4, July 2026.
ABSTRACT Background and aims Non‐alcoholic Fatty Liver Disease (NAFLD) affects about a quarter of the world's population. Liver biopsy remains the gold standard for diagnosing the progressive form of NAFLD called Non‐alcoholic Steatohepatitis (NASH) but it is invasive, prone to sampling errors and observer variability, and impractical for widespread ...
Anna Negroni, Luisa Pieroni, Noemi Fiaschini, Francesca Palone, Mariateresa Mancuso, Roberta Vitali   +5 more
wiley   +1 more source

Covalent attachment of chymotrypsin to poly[N-(2-hydroxypropyl)methacrylamide]

, 1981
Chymotrypsin has been covalently bound on a water-soluble biocompatible carrier poly[N-(2-hydroxypropyl)methacrylamide] by three different methods. The catalytic activity of the polymer bound enzyme in the reaction with low-molecular substrates coincided
Peeter Sikk, Mati Haga, Aavo Aaviksaar, Ants Lääne, Vladimír Chytrý, Jindřich Kopeček   +5 more
core   +1 more source

Improving the functional and technological properties of minced pork using a proteolytic enzyme

Теория и практика переработки мяса
The use of pork obtained from intensively growing hybrid animals as the main raw material in meat processing, in particular sausage production, is accompanied by undesirable variability of consumer characteristics of sausage products and a decrease in ...
A. A. Semenova, T. G. Kuznetsova, O. A. Seliverstova, M. N. Salikova, M. E. Spirina, Yu. M. Bukhteeva   +5 more
doaj   +1 more source

Mass spectrometry proteomics for studying mitostasis

Protein Science, Volume 35, Issue 7, July 2026.
Abstract Maintaining mitochondrial integrity and function is fundamental to cellular homeostasis. Cells rely on coordinated protein quality control (QC) systems—including intricate chaperone‐protease networks, the ubiquitin‐proteasome system, and cytosolic surveillance pathways—that together form a dynamic, cell‐wide mitostasis network governing the ...
Lakshita Sharma, Sristi Chakroborty, Hirak Das, Silke Oeljeklaus, Julian Bender, Bettina Warscheid   +5 more
wiley   +1 more source

Modulation of Digestive Enzyme Activities and Intestinal γ-Proteobacteria in Gilthead Sea Bream Fed High-Fat Diets Supplemented with HIDROX^® Olive Oil Extract

Animals
High-fat diets are commonly used in fish farming due to their protein-sparing effect, contributing to reduced production costs. However, this practice may have adverse effects such as metabolic impairment and inflammation.
Irene García-Meilán, Sara Balbuena-Pecino, Manel Montblanch, Sara Ramos-Romero, Ramón Fontanillas, Joaquim Gutiérrez, Encarnación Capilla, Isabel Navarro, Ángeles Gallardo   +8 more
doaj   +1 more source

The pivotal role of β‐lactone stereochemistry in the development of SARS‐CoV‐2 Mpro inhibitors

Protein Science, Volume 35, Issue 7, July 2026.
Abstract From the arrival of the SARS‐CoV‐2 coronavirus in 2019 and its associated COVID‐19 pandemic, worldwide efforts have been focused on developing a drug to treat patients. The SARS‐CoV‐2 main protease (Mpro) is one of the main targets for drug design due to its key role in the virus replication and its distinguished ability to cleave peptides ...
Katarzyna Świderek, Vicent Moliner
wiley   +1 more source