Results 31 to 40 of about 21,238 (208)

Presynaptic Membrane Receptors Modulate ACh Release, Axonal Competition and Synapse Elimination during Neuromuscular Junction Development

Frontiers in Molecular Neuroscience, 2017
During the histogenesis of the nervous system a lush production of neurons, which establish an excessive number of synapses, is followed by a drop in both neurons and synaptic contacts as maturation proceeds.
Josep Tomàs, Neus Garcia, Maria A. Lanuza, Manel M. Santafé, Marta Tomàs, Laura Nadal, Erica Hurtado, Anna Simó, Víctor Cilleros   +8 more
doaj   +1 more source

Synaptic Activity and Muscle Contraction Increases PDK1 and PKCβI Phosphorylation in the Presynaptic Membrane of the Neuromuscular Junction

Frontiers in Molecular Neuroscience, 2017
Conventional protein kinase C βI (cPKCβI) is a conventional protein kinase C (PKC) isoform directly involved in the regulation of neurotransmitter release in the neuromuscular junction (NMJ).
Erica Hurtado, Víctor Cilleros, Laia Just, Anna Simó, Laura Nadal, Marta Tomàs, Neus Garcia, Maria A. Lanuza, Josep Tomàs   +8 more
doaj   +1 more source

Assessment of the gene mosaicism burden in blood and its implications for immune disorders

Scientific Reports, 2021
There are increasing evidences showing the contribution of somatic genetic variants to non-cancer diseases. However, their detection using massive parallel sequencing methods still has important limitations.
Manuel Solís-Moruno, Anna Mensa-Vilaró, Laura Batlle-Masó, Irene Lobón, Núria Bonet, Tomàs Marquès-Bonet, Juan I. Aróstegui, Ferran Casals   +7 more
doaj   +1 more source

Interventions across the retirement transition for improving well-being: a scoping review protocol

BMJ Open, 2019
Introduction The work-to-retirement transition involves a process of psychologically and behaviourally distancing oneself from the workforce that is often accompanied by other social changes.
Miriam Rodríguez-Monforte, Carles Fernández-Jané, Anna Martin-Arribas, Mercè Sitjà-Rabert, Olga Canet Vélez, Montserrat Sanromà-Ortiz, Jordi Vilaró, Elena Carrillo-Alvarez   +7 more
doaj   +1 more source

Benestar emocional, qualitat de vida i resiliència en l’alumnat universitari: un estudi comparatiu entre variables sociodemogràfiques i acadèmiques

Revista d'Innovació i Recerca en Educació
INTRODUCCIÓ. L’inici de la universitat és una etapa de canvis i exigències que pot augmentar la vulnerabilitat de l’alumnat als problemes de salut mental, fent que factors com la resiliència, la satisfacció vital, la qualitat de vida i l’esgotament ...
Cristina Cañete-Massé, Maribel Peró-Cebollero, Joan Guàrdia-Olmos, Juan-Antonio Amador-Campos, Virginia Krieger   +4 more
doaj   +1 more source

The prohibitin-binding compound fluorizoline inhibits mitophagy in cancer cells

Oncogenesis, 2021
Fluorizoline is a prohibitin-binding compound that triggers apoptosis in several cell lines from murine and human origin, as well as in primary cells from hematologic malignancies by inducing the integrated stress response and ER stress. Recently, it was
Sonia Núñez-Vázquez, José Saura-Esteller, Ismael Sánchez-Vera, Emma Guilbaud, Ana M. Cosialls, Gabriel Pons, Jean-Ehrland Ricci, Daniel Iglesias-Serret, Sandrine Marchetti, Joan Gil   +9 more
doaj   +1 more source

Obesity-promoting factors in Mexican children and adolescents: challenges and opportunities [PDF]

Global Health Action, 2016
Background: Mexico is a developing country with one of the highest youth obesity rates worldwide; >34% of children and adolescents between 5 and 19 years of age are overweight or obese.
Magaly Aceves-Martins, Elisabet Llauradó, Lucia Tarro, Rosa Solà, Montse Giralt   +4 more
doaj   +1 more source

The “Healthy Meals” web app for the assessment of nutritional content and food allergens in restaurant meals: Development, evaluation and validation

Digital Health, 2022
Objective The development and the evaluation of the Healthy Meals web app designed for professionals from different disciplines related to food, aimed to assess the nutritional and food allergen content of restaurant meals, was described.
Floriana Mandracchia, Lucia Tarro, Elisabet Llauradó, Rosa M. Valls, Rosa Solà   +4 more
doaj   +1 more source

Muscle Contraction Regulates BDNF/TrkB Signaling to Modulate Synaptic Function through Presynaptic cPKCα and cPKCβI

Frontiers in Molecular Neuroscience, 2017
The neurotrophin brain-derived neurotrophic factor (BDNF) acts via tropomyosin-related kinase B receptor (TrkB) to regulate synapse maintenance and function in the neuromuscular system.
Erica Hurtado, Víctor Cilleros, Laura Nadal, Anna Simó, Teresa Obis, Neus Garcia, Manel M. Santafé, Marta Tomàs, Katherine Halievski, Cynthia L. Jordan, Maria A. Lanuza, Josep Tomàs   +11 more
doaj   +1 more source

Impact of lung cancer screening eligibility criteria on participants' characteristics and healthcare resources

International Journal of Cancer, EarlyView.
What's New? Inclusion criteria for lung cancer screening (LCS) maintain cost control by focusing resources on select high‐risk groups. However, eligible individuals are inherently dissimilar in risk profile and demographics, potentially impacting LCS effectiveness and uptake.
María Olivia Cabrera, Kevin ten Haaf, Josep Maria Borràs, Rebeca Font, Judit Solà, Juul Hubert, Mónica Ballesteros, Josep Alfons Espinàs   +7 more
wiley   +1 more source