Results 31 to 40 of about 161,804 (236)

The prohibitin-binding compound fluorizoline inhibits mitophagy in cancer cells

Oncogenesis, 2021
Fluorizoline is a prohibitin-binding compound that triggers apoptosis in several cell lines from murine and human origin, as well as in primary cells from hematologic malignancies by inducing the integrated stress response and ER stress. Recently, it was
Sonia Núñez-Vázquez, José Saura-Esteller, Ismael Sánchez-Vera, Emma Guilbaud, Ana M. Cosialls, Gabriel Pons, Jean-Ehrland Ricci, Daniel Iglesias-Serret, Sandrine Marchetti, Joan Gil   +9 more
doaj   +1 more source

Interventions across the retirement transition for improving well-being: a scoping review protocol

BMJ Open, 2019
Introduction The work-to-retirement transition involves a process of psychologically and behaviourally distancing oneself from the workforce that is often accompanied by other social changes.
Miriam Rodríguez-Monforte, Carles Fernández-Jané, Anna Martin-Arribas, Mercè Sitjà-Rabert, Olga Canet Vélez, Montserrat Sanromà-Ortiz, Jordi Vilaró, Elena Carrillo-Alvarez   +7 more
doaj   +1 more source

Obesity-promoting factors in Mexican children and adolescents: challenges and opportunities [PDF]

Global Health Action, 2016
Background: Mexico is a developing country with one of the highest youth obesity rates worldwide; >34% of children and adolescents between 5 and 19 years of age are overweight or obese.
Magaly Aceves-Martins, Elisabet Llauradó, Lucia Tarro, Rosa Solà, Montse Giralt   +4 more
doaj   +1 more source

Oxygen Biosensors and Control in 3D Physiomimetic Experimental Models

Antioxidants, 2021
Traditional cell culture is experiencing a revolution moving toward physiomimetic approaches aiming to reproduce healthy and pathological cell environments as realistically as possible.
Jorge Otero, Anna Ulldemolins, Ramon Farré, Isaac Almendros   +3 more
doaj   +1 more source

Experiències d'aula amb el treball amb controvèrsies sòcio-científiques. Educació per al desenvolupament i la salut, pseudociències i eines per a l'avaluació d'activitats

Ciències, 2016
Les controvèrsies sòcio-científiques (o CSC) i la Recerca i Innovació Responsables són contexts candidats per a ubicar l’ensenyament de les ciències en conflictes rellevants.
Jordi Domènech-Casal, Iván Marchán-Carvajal, Quique Vergara   +2 more
doaj   +1 more source

The “Healthy Meals” web app for the assessment of nutritional content and food allergens in restaurant meals: Development, evaluation and validation

Digital Health, 2022
Objective The development and the evaluation of the Healthy Meals web app designed for professionals from different disciplines related to food, aimed to assess the nutritional and food allergen content of restaurant meals, was described.
Floriana Mandracchia, Lucia Tarro, Elisabet Llauradó, Rosa M. Valls, Rosa Solà   +4 more
doaj   +1 more source

Experimental Setting for Applying Mechanical Stimuli to Study the Endothelial Response of Ex Vivo Vessels under Realistic Pathophysiological Environments

Life, 2021
This paper describes the design, construction and testing of an experimental setting, making it possible to study the endothelium under different pathophysiological conditions.
Ana Osuna, Anna Ulldemolins, Hector Sanz-Fraile, Jorge Otero, Núria Farré, Ramon Farré, Isaac Almendros   +6 more
doaj   +1 more source

Muscle Contraction Regulates BDNF/TrkB Signaling to Modulate Synaptic Function through Presynaptic cPKCα and cPKCβI

Frontiers in Molecular Neuroscience, 2017
The neurotrophin brain-derived neurotrophic factor (BDNF) acts via tropomyosin-related kinase B receptor (TrkB) to regulate synapse maintenance and function in the neuromuscular system.
Erica Hurtado, Víctor Cilleros, Laura Nadal, Anna Simó, Teresa Obis, Neus Garcia, Manel M. Santafé, Marta Tomàs, Katherine Halievski, Cynthia L. Jordan, Maria A. Lanuza, Josep Tomàs   +11 more
doaj   +1 more source

Membrane Receptor-Induced Changes of the Protein Kinases A and C Activity May Play a Leading Role in Promoting Developmental Synapse Elimination at the Neuromuscular Junction

Frontiers in Molecular Neuroscience, 2017
Synapses that are overproduced during histogenesis in the nervous system are eventually lost and connectivity is refined. Membrane receptor signaling leads to activity-dependent mutual influence and competition between axons directly or with the ...
Josep M. Tomàs, Neus Garcia, Maria A. Lanuza, Laura Nadal, Marta Tomàs, Erica Hurtado, Anna Simó, Víctor Cilleros   +7 more
doaj   +1 more source

Adolescents encouraging healthy lifestyles through a peer‐led social marketing intervention: Training and key competencies learned by peer leaders

Health Expectations, 2022
Background Adolescents who participate as peer leaders can benefit and acquire competencies from their peer leadership experience. Objectives To identify the competencies gained by adolescents who participated as peer leaders in a healthy lifestyle study
Elisabet Llauradó, Magaly Aceves‐Martins, Jordi Prades‐Tena, Maria Besora‐Moreno, Ignasi Papell‐Garcia, Montse Giralt, Amy Davies, Lucia Tarro, Rosa Solà   +8 more
doaj   +1 more source