Results 31 to 40 of about 1,401,302 (280)
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Helena Antipoff: ciência, compromisso social e solidariedade sem fronteiras
Revista Cocar, 2018 Este artigo tem o objetivo de revisitar as contribuições de Helena Antipoff (1892-1974) para a Educação brasileira. No final dos anos 20, Antipoff chegou ao Brasil contribuindo com conhecimento trazido de grandes centros de pesquisa na época, como França, SuÃça e da sua experiência na sua terra natal, a União Soviética.
França, Ana Raquel de Oliveira +1 more
openaire +1 more source
Creative tourism special issue: foreword [PDF]
, 2019 This Tourism and Management Studies Special Issue on Creative Tourism is born under the scope of a very original project: the CREATOUR - Creative Tourism Destination Development in Small Cities and Rural Areas.
Cabeça, Sónia Moreira +3 more
core
Synthesis and Antileishmanial Activity of 1,2,4,5-Tetraoxanes against Leishmania donovani [PDF]
, 2020 A chemically diverse range of novel tetraoxanes was synthesized and evaluated in vitro against intramacrophage amastigote forms of Leishmania donovani. All 15 tested tetraoxanes displayed activity, with IC50 values ranging from 2 to 45 µm.
Amado, Patrícia +5 more
core +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Protein O‐glycosylation in the Bacteroidota phylum
FEBS Open Bio, EarlyView.Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns +2 more
wiley +1 more source
EDITORES ASSOCIADOS E REVISORES AD HOC
Ciência Florestal, 2011 .
Ciência Florestal
doaj +1 more source
Acerca de los "hábitos artificiales" en la antropología luliana y el ascenso espiritual del hombre [PDF]
, 2005 The concept of "habitus artificialis" in lullian anthropology involves the knowledge of the divines virtues -the nature's secrets-, and it represents the spiritual way of human being. Similarly, some documents of medieval universities contain the natural
Higuera Rubio, José +1 more
core +1 more source
Contributo dos blogues de ciência para a construção da literacia científica cívica no século XXI [PDF]
, 2013 Numa sociedade marcada pela superabundância de informação que exige, cada vez mais, o posicionamento crítico dos cidadãos, os blogues de ciência constituem um dos modos de interação possível para o debate de tópicos com relevância para um exercício de ...
Malho, Arminda +2 more
core +2 more sources
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
FEBS Open Bio, EarlyView.We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source