Results 31 to 40 of about 1,395,927 (228)

Portuguese Adaptation of Students' Engagement in Schools International Scale (SESIS) [PDF]

, 2012
This work is financed by National Founds through FCT - Fundação para a Ciência e Tecnologia, in the context of the project PTDC/CPE-CED/114362/2009- Students Engagement in Schools: Differentiation and Promotion, coordinated by Prof. Feliciano H.
Almeida, Ana, Bahia, Sara, Caldeira, Suzana, Carvalho, Carolina, Conboy, Jay, Festas, Maria Isabel, Galvão, Diana, Janeiro, Isabel Nunes, Melo, Madalena, Nogueira, João, Pereira, Tiago, Taveira, Maria do Céu, Veiga, Feliciano Henriques   +12 more
core  

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Comunicação de Ciência - Porquê, como e para quem falar de ciência [PDF]

, 2017
Por que é que os seminários dos cientistas te parecem todos iguais? Quantas vezes assististe a apresentações sobre o que deveria ter sido um tema inspirador, para apenas seres embalado ao ritmo de um tom monocórdico letrado por jargão científico?
Nobre, Alexandra, Pacheco, Andreia Sofia Alves Pinto, Ribeiro, Daniel   +2 more
core  

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Students’ Engagement in School: A literature review [PDF]

, 2012
This work is financed by National Founds through FCT-Fundação para a Ciência e Tecnologia, in the context of the project PTDC/CPE-CED/114362/2009- Students Engagement in Schools: Differentiation and Promotion, coordinated by Prof. Feliciano H.
Almeida, Ana, Bahia, Sara, Caldeira, Suzana, Carvalho, Carolina, CONBOY, JOSEPH, Festas, Maria Isabel, Galvão, Diana, Janeiro, Isabel Nunes, Melo, Madalena, Nogueira, João, Pereira, Tiago, Taveira, Maria do Céu, Veiga, Feliciano Henriques   +12 more
core  

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana, Mariana Maschietto, Daniela Paz Leal, Ricardo de Santos de Oliveira, Mayara Ferreira Euzébio, Antonio Carlos dos Santos, Luciano Neder, Carlos Alberto Scrideli, Elvis Terci Valera   +8 more
wiley   +1 more source

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

Extrato de alho melhora a superação da dormência de videiras ‘Niagara Rosada’em regiões subtropicais. [PDF]

, 2010
Nas regiões com invernos amenos, normalmente as exigências de frio para a quebra de dormência de gemas de videiras não são atendidas, e apenas os produtos altamente tóxicos CaCN2 e H2CN2 são recomendados na viticultura convencional para quebra de ...
Botelho, Renato Vasconcelos, Moura, Mara Fernandes, Pires, Erasmo José Paioli, Tecchio, Marco Antonio, Terra, Maurilo Monteiro   +4 more
core   +2 more sources

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source