Results 11 to 20 of about 13,801 (245)

Progressive multifocal leucoencephalopathy in an immunocompetent patient with favourable outcome. A case report [PDF]

BMC Neurology, 2010
Background To report the clinical course of PML in an apparently immunocompetent patient treated with cidofovir. Case Presentation A 35-year-old immunocompetent man who developed progressive hemianopsia, aphasia, and limb weakness underwent repeated MRI ...
Mørk Sverre J, Rinaldo Christine H, Storstein Anette, Glad Solveig, Naess Halvor, Myhr Kjell-Morten, Hirsch Hans   +6 more
doaj   +2 more sources

The broad-spectrum anti-DNA virus agent cidofovir inhibits lung metastasis of virus-independent, FGF2-driven tumors [PDF]

, 2014
The FDA-approved anti-DNA virus agent cidofovir (CDV) is being evaluated in phase II/III clinical trials for the treatment of human papillomavirus (HPV)-associated tumors.
Sandra Liekens, Sam Noppen, Sofie Gijsbers, Rebecca Sienaert, Roberto Ronca, Chiara Tobia, Marco Presta   +6 more
openalex   +3 more sources

Cyclic cidofovir (cHPMPC) prevents congenital cytomegalovirus infection in a guinea pig model [PDF]

, 2006
Background Congenital cytomegalovirus (CMV) infection is a major public health problem. Antiviral therapies administered during pregnancy might prevent vertical CMV transmission and disease in newborns, but these agents have not been evaluated in ...
Mark R. Schleiss, Jodi Anderson, Alistair McGregor   +2 more
openalex   +4 more sources

Targeting Genome Maintenance Defects of Cancers Using Chain-Terminating Nucleoside Analogs. [PDF]

Cancer Sci
Nucleoside analogs interfere with DNA replication either by their chain‐terminating properties or by serving as DNA damage on the template. The genome maintenance pathways required to maintain cellular tolerance to each nucleoside analog vary depending on the drug.
Kawasumi R, E Tabassum R, Hirota K.
europepmc   +2 more sources

Adenovirus-Associated Opsoclonus After Allogeneic Hematopoietic Stem Cell Transplantation. [PDF]

EJHaem
eJHaem, Volume 7, Issue 2, April 2026.
Miyajima T, Hoshino S, Nojima S, Shiratori S, Iwanami T, Teshima T.   +5 more
europepmc   +2 more sources

Topical Astodrimer Sodium, a Non-Toxic Polyanionic Dendrimer, Demonstrates Antiviral Activity in an Experimental Ocular Adenovirus Infection Model

Molecules, 2021
There is no approved antiviral therapy for adenovirus (HAdV) ocular infections. Astodrimer sodium (SPL7013) is a polyanionic dendrimer with antiviral activity.
Eric G. Romanowski, Kathleen A. Yates, Jeremy R. A. Paull, Graham P. Heery, Robert M. Q. Shanks   +4 more
doaj   +1 more source

Ranpirnase (OKG-0301), a Novel Ribonuclease, Demonstrates Antiviral Activity against Adenovirus in the Ad5/NZW Rabbit Ocular Replication Model

Pathogens, 2022
Adenovirus ocular infections are common ocular viral infections seen worldwide, for which there is no approved antiviral therapy available. Ranpirnase is a novel ribonuclease which preferentially degrades tRNA resulting in an inhibition of protein ...
Eric G. Romanowski, Kathleen A. Yates, Eric J. Daniels, Brian M. Strem, John E. Romanowski, Regis P. Kowalski   +5 more
doaj   +1 more source

Successful Treatment of Severe Adenoviral ARDS Using Cidofovir in a Case with Cerebral Palsy

Journal of Pediatric Emergency and Intensive Care Medicine, 2021
Adenovirus is a non-enveloped, double-stranded DNA virus that can cause infections in the upper and lower respiratory tract, conjunctiva, and gastrointestinal tract. Adenovirus infections are usually mild but may cause mortality and morbidity, especially
Emrah Gün, Tanıl Kendirli, Merve Havan, Serhan Özcan, Serdar Balsak, Edin Botan, Hatice Kübra Konca, Erdal İnce   +7 more
doaj   +1 more source

BK Virus Pneumonia with CMV Colitis in a Kidney Transplant Recipient: First Successful Treatment with Non-Cidofovir Based Therapy

Journal of Microbiology and Infectious Diseases, 2021
BK virus (BKV) pneumonia is a rare entity especially seen in immunosuppressed patients, for which cidofovir is the used treatment option. We describe a case of a young female patient who presented for altered kidney function six months following kidney ...
Ali Chaito, Mouhamad Nasser, Hussein Karnib, Amal Hamieh   +3 more
doaj   +1 more source

Intralesional cidofovir for the treatment of recalcitrant periungual warts

Journal of Dermatological Treatment, 2023
Purpose: Successful treatment of periungual warts presents a clinical challenge, as many are refractory or represent following conventional treatments.
McKayla Poppens, Jeremy Davis
doaj   +1 more source