Results 1 to 10 of about 12,424 (198)
Cidofovir Activity against Poxvirus Infections
Viruses, 2010 Cidofovir [(S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine, HPMPC] is an acyclic nucleoside analog approved since 1996 for clinical use in the treatment of cytomegalovirus (CMV) retinitis in AIDS patients.
Graciela Andrei, Robert Snoeck
exaly +3 more sources
Progressive multifocal leucoencephalopathy in an immunocompetent patient with favourable outcome. A case report [PDF]
BMC Neurology, 2010 Background To report the clinical course of PML in an apparently immunocompetent patient treated with cidofovir. Case Presentation A 35-year-old immunocompetent man who developed progressive hemianopsia, aphasia, and limb weakness underwent repeated MRI ...
Mørk Sverre J +6 more
doaj +2 more sources
Treatment of Severe Ocular Mpox with Cidofovir and Tecovirimat [PDF]
Emerging Infectious DiseasesMpox, a reemerging zoonotic disease since 2022, primarily affects the skin; ocular involvement is rarely reported. We present a case of mpox-caused disciform keratitis treated with a combination of cidofovir and tecovirimat.
Xavier Brousse +8 more
doaj +2 more sources
Assessment of three antiviral compounds against Borealpox virus infection in a mouse model [PDF]
Emerging Microbes and InfectionsBorealpox virus (BRPV) is a zoonotic orthopoxvirus which was first documented in Alaska in 2015. Although most human infections are mild, a recent fatal case in an immunocompromised individual highlights the importance of studying this emerging pathogen.
Jérémie Prévost +7 more
doaj +2 more sources
Real World Experience using Cidofovir in BK Polyomavirus Haemorrhagic Cystitis following Stem Cell Transplantation-Are Generics Equally Efficacious? [PDF]
Journal of Clinical and Diagnostic Research, 2022 Introduction: BK Polyomavirus induced Haemorrhagic Cystitis (BKPyV-HC), a well-recognised complication following Haematopoietic Cell Transplantation (HCT), is associated with increased organ dysfunction and mortality.
Sharon Lionel +7 more
doaj +1 more source
Monkeypox transmission: time to revisit the medical strategy of public health [PDF]
Infectious Diseases and Tropical Medicine, 2023 Viral disease outbreaks pose an unprecedented challenge to public health, particularly in areas with limited access to healthcare and infection control resources. Monkeypox is a rare viral zoonosis associated with the monkeypox virus.
S. Prajapati +5 more
doaj +1 more source
Outcomes of early administration of cidofovir in non-immunocompromised patients with severe adenovirus pneumonia. [PDF]
PLoS ONE, 2015 The benefits of treatment with antiviral therapy for severe adenovirus (AdV) pneumonia are not well established. We described the clinical characteristics and treatment outcomes of early cidofovir treatment of severe AdV pneumonia in non ...
Se Jin Kim +4 more
doaj +1 more source
Molecules, 2021 There is no approved antiviral therapy for adenovirus (HAdV) ocular infections. Astodrimer sodium (SPL7013) is a polyanionic dendrimer with antiviral activity.
Eric G. Romanowski +4 more
doaj +1 more source
Viruses, 2021 Bovine herpesvirus-1 (BoHV-1) infection contributes to keratoconjunctivitis, respiratory disease, and reproductive losses in cattle. The objective of this study was to determine the most appropriate ophthalmic antiviral agent for BoHV-1 inhibition using ...
Christopher R. Alling +6 more
doaj +1 more source
Frontiers in Veterinary Science, 2023 Feline herpesvirus type 1 (FHV-1) commonly causes ocular surface disease in cats and is treated with antiviral medications targeting viral DNA polymerase (UL30/42).
Andrew C. Lewin +8 more
doaj +1 more source