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Cidofovir Activity against Poxvirus Infections
Cidofovir [(S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine, HPMPC] is an acyclic nucleoside analog approved since 1996 for clinical use in the treatment of cytomegalovirus (CMV) retinitis in AIDS patients.
Robert Snoeck +2 more
exaly +3 more sources
Treatment of Severe Ocular Mpox with Cidofovir and Tecovirimat [PDF]
Mpox, a reemerging zoonotic disease since 2022, primarily affects the skin; ocular involvement is rarely reported. We present a case of mpox-caused disciform keratitis treated with a combination of cidofovir and tecovirimat.
Xavier Brousse +8 more
doaj +2 more sources
Real World Experience using Cidofovir in BK Polyomavirus Haemorrhagic Cystitis following Stem Cell Transplantation-Are Generics Equally Efficacious? [PDF]
Introduction: BK Polyomavirus induced Haemorrhagic Cystitis (BKPyV-HC), a well-recognised complication following Haematopoietic Cell Transplantation (HCT), is associated with increased organ dysfunction and mortality.
Sharon Lionel +7 more
doaj +1 more source
Monkeypox transmission: time to revisit the medical strategy of public health [PDF]
Viral disease outbreaks pose an unprecedented challenge to public health, particularly in areas with limited access to healthcare and infection control resources. Monkeypox is a rare viral zoonosis associated with the monkeypox virus.
S. Prajapati +5 more
doaj +1 more source
There is no approved antiviral therapy for adenovirus (HAdV) ocular infections. Astodrimer sodium (SPL7013) is a polyanionic dendrimer with antiviral activity.
Eric G. Romanowski +4 more
doaj +1 more source
Outcomes of early administration of cidofovir in non-immunocompromised patients with severe adenovirus pneumonia. [PDF]
The benefits of treatment with antiviral therapy for severe adenovirus (AdV) pneumonia are not well established. We described the clinical characteristics and treatment outcomes of early cidofovir treatment of severe AdV pneumonia in non ...
Se Jin Kim +4 more
doaj +1 more source
Bovine herpesvirus-1 (BoHV-1) infection contributes to keratoconjunctivitis, respiratory disease, and reproductive losses in cattle. The objective of this study was to determine the most appropriate ophthalmic antiviral agent for BoHV-1 inhibition using ...
Christopher R. Alling +6 more
doaj +1 more source
Adenovirus ocular infections are common ocular viral infections seen worldwide, for which there is no approved antiviral therapy available. Ranpirnase is a novel ribonuclease which preferentially degrades tRNA resulting in an inhibition of protein ...
Eric G. Romanowski +5 more
doaj +1 more source
Successful Treatment of Severe Adenoviral ARDS Using Cidofovir in a Case with Cerebral Palsy
Adenovirus is a non-enveloped, double-stranded DNA virus that can cause infections in the upper and lower respiratory tract, conjunctiva, and gastrointestinal tract. Adenovirus infections are usually mild but may cause mortality and morbidity, especially
Emrah Gün +7 more
doaj +1 more source
BK virus (BKV) pneumonia is a rare entity especially seen in immunosuppressed patients, for which cidofovir is the used treatment option. We describe a case of a young female patient who presented for altered kidney function six months following kidney ...
Ali Chaito +3 more
doaj +1 more source

