Foscarnet Versus Ganciclovir for Severe Congenital Cytomegalovirus Infection: Short- and Long-Term Follow-Up [PDF]
VirusesBackground: Cytomegalovirus (CMV) infection is the most common and serious congenital infection, with universal screening in pregnancy, standardized therapy, and a vaccine still lacking.
Giovanni Nigro +4 more
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Intravitreal foscarnet is an effective adjunct after systemic therapy failure in pediatric antiviral-resistant cytomegalovirus retinitis [PDF]
Journal of International Medical ResearchThis report describes the case of a school-aged male child with T-cell acute lymphoblastic leukemia who developed cytomegalovirus retinitis despite systemic antiviral therapy.
Iden Amiri +3 more
doaj +2 more sources
Management of CMV encephalitis with persistent CSF CMV DNA in a patient with HIV: a case report of successful treatment with ganciclovir–foscarnet combination therapy [PDF]
BMC Infectious DiseasesBackground Cytomegalovirus (CMV) is a common opportunistic pathogen in immunocompromised individuals and can lead to significant mortality and morbidity via end-organ involvements.
Elif Tanyel +4 more
doaj +2 more sources
Foscarnet-induced penile ulcer in a patient with cytomegalovirus coinfection refractory to ganciclovir and Clostridioides difficile: A case report [PDF]
IDCasesCoinfections by cytomegalovirus and Clostridioides difficile are rare and can be life-threatening, especially in immunosuppressed patients. Their symptoms often overlap, thus generating a great diagnostic challenge, with the need for multiple diagnostic ...
John Jairo Cardeño-Sánchez +3 more
doaj +2 more sources
Reversion of Val(Ganciclovir)-Resistance-Associated Mutations in Two SOT Patients with Mismatched Serostatus for CMV (D+/R-) [PDF]
VirusesThe emergence of drug-resistant cytomegalovirus (CMV) complicates viral response to therapy. We present two cases of solid organ transplant (SOT) recipients, highlighting the reversion of UL97 mutations associated with val(ganciclovir) resistance ...
Elena Seminari +9 more
doaj +2 more sources
Treatment of gastroparesis with botulinum toxin in patient after allogenic bone marrow transplantation [PDF]
Терапевтический архив, 2018 The case report of botulinum toxin treatment of gastroparesis in a patient following allogenic bone marrow transplantation is described. The causes of gastroparesis and methods of prevention and treatment are discussed.
G.M. GALSTYAN +6 more
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Resistance to antiviral drugs in human viruses from the subfamily Betaherpesvirinae
Вопросы вирусологии, 2022 The review provides information on the mechanisms of the emergence of resistance to antiviral drugs in human viruses from the subfamily Betaherpesvirinae. Data on the principles of action of antiviral drugs and their characteristics are given.
Mikhail V. Demin +3 more
doaj +1 more source
Anti-N-methyl-D-aspartate receptor encephalitis 8 years after serial herpes simplex virus type 1 and human herpesvirus type 7 encephalitis [PDF]
Encephalitis, 2021 Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is triggered by herpesvirus encephalitis. Human herpesvirus type 7 (HHV-7) is a recently described herpesvirus for which neuroinvasion has been reported rarely.
Yoonhyuk Jang +7 more
doaj +1 more source
Current Drugs to Treat Infections with Herpes Simplex Viruses-1 and -2
Viruses, 2021 Herpes simplex viruses-1 and -2 (HSV-1 and -2) are two of the three human alphaherpesviruses that cause infections worldwide. Since both viruses can be acquired in the absence of visible signs and symptoms, yet still result in lifelong infection, it is ...
Lauren A. Sadowski +3 more
doaj +1 more source
Pharmaceuticals, 2023 Cytomegalovirus (CMV) infection is a relevant cause of morbimortality in patients receiving allogeneic stem cell transplantation (allo-HCT). Foscarnet (FCN) is an effective drug against CMV administered intravenously and usually on an inpatient basis ...
Sonia Ruiz-Boy +16 more
doaj +1 more source