Results 11 to 20 of about 9,903 (207)

CMV Preventive and Treatment Studies in Children Undergoing Haematopoietic Stem Cell Transplant: A Systematic Review. [PDF]

Rev Med Virol
ABSTRACT Cytomegalovirus (CMV) is one of the most important infectious causes of morbidity and mortality in children undergoing haematopoietic stem cell transplant (HSCT). However, the evidence for preventing and treating CMV disease in children in this context remains limited. We sought to review the current available evidence regarding the prevention
Fusani L, Fusco E, Fonseca M, Breuer J, Rao K, Galli L, Bamford A, Kadambari S.   +7 more
europepmc   +2 more sources

Acyclovir-Resistant Herpes Simplex Virus in Pediatric Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplant: A Case Series. [PDF]

Transpl Infect Dis
This retrospective case series of acyclovir‐resistant HSV infection in pediatric patients undergoing allogeneic HSCT discusses the clinical course, associated complications, and treatment, including side effects. We propose the first algorithm for investigating and managing acyclovir‐resistant HSV infections in pediatric HSCT recipients, highlighting ...
Nunn J, Ahmed A, Senthil S, Mirci-Danicar O, Bonney D, Horgan C, Mustafa O, Wynn R, Guiver M, Nataraj R.   +9 more
europepmc   +2 more sources

Characteristics of Acyclovir-Resistant Herpes Simplex Virus Infection in Hematological Patients. [PDF]

J Oral Pathol Med
ABSTRACT Objective Acyclovir‐resistant herpes simplex virus infections pose a significant challenge in immunosuppressed patients. This study aimed to characterize the clinical features, treatment outcomes, and mortality associated with acyclovir‐resistant herpes simplex virus infection. Materials and Methods A retrospective analysis was conducted on 18
Shehadeh R, Bar Ilan M, Dovrat S, Yerushalmi R, Tepperberg Oikawa M, Piperi E, Nikitakis NG, Yarom N.   +7 more
europepmc   +2 more sources

Risk of Acute Kidney Injury Associated With Nephrotoxic Burden in Hospitalized Patients: A Scoping Review. [PDF]

Clin Pharmacol Ther
Limited evidence exists synthesizing the risk of acute kidney injury (AKI) associated with the concomitant administration of multiple nephrotoxic drugs, and even less examining the concept of nephrotoxic burden. The objective of this scoping review was to (1) identify definitions of nephrotoxic burden; (2) methods used to quantify (use of calculations)
Alatawi W, Wallace JL, Rungkitwattanakul D, Stottlemyer BA, Tran TL, Reida MM, Kane-Gill SL.   +6 more
europepmc   +2 more sources

Comparison of intravitreal ganciclovir monotherapy and combination with foscarnet as initial therapy for cytomegalovirus retinitis [PDF]

International Journal of Ophthalmology, 2018
AIM: To compare the effectiveness between multiple intravitreal injections of ganciclovir alone and combined with foscarnet as initial treatment for patients with newly-onset cytomegalovirus retinitis (CMVR). METHODS: The retrospective study observed 37
Jing-Jing Fan, Yong Tao, De-Kuang Hwang
doaj   +1 more source

Kyrieleis Arteriolitis Associated with Acute Retinal Necrosis Due to Herpes Simplex Virus Type 1 Secondary to Herpetic Encephalitis

Vision, 2022
We report the case of a 52-year-old woman who presented to the emergency department with acute retinal necrosis in her left eye secondary to herpes simplex virus type 1 encephalitis for which she had been hospitalized four months before.
Olga E. Makri, Iasonas K. Tsekouras, Leonidia Leonidou, Konstantinos Kagkelaris, Vassilios Kozobolis, Constantinos D. Georgakopoulos   +5 more
doaj   +1 more source

Validated Modernized Assay for Foscarnet in Pharmaceutical Formulations Using Suppressed Ion Chromatography Developed through a Quality by Design Approach

Separations, 2021
Inspired by the United States Pharmacopoeia (USP) “monograph modernization” initiative, we developed and validated an assay for foscarnet sodium injection solution (“foscavir”), following quality by design (QbD) principles, incorporating design of ...
Ngoc Phuoc Dinh, Adel Shamshir, Gjani Hulaj, Tobias Jonsson   +3 more
doaj   +1 more source

Foscarnet-induced genital lesions: An overview with a case report

Dermatology Reports, 2018
Foscarnet is an important antiviral medication used mainly in the treatment of complicated Herpes-simplex virus and cytomegalovirus (CMV) infections. Reported first in the 1990’s, genital ulcers are a potential side effect in about 10% of cases.
Jonas A. Adalsteinsson, Michael Pan, Shivani Kaushik, Jonathan Ungar   +3 more
doaj   +1 more source

In vitro susceptibility of six isolates of equine herpesvirus 1 to acyclovir, ganciclovir, cidofovir, adefovir, PMEDAP and foscarnet [PDF]

, 2007
International ...
Croubels, Siska, De Backer, Patrick, Garré, Barbara, Nauwynck, Hans, NEYTS, J, NUGENT, J, VAN DER MEULEN, K   +6 more
core   +3 more sources

Cytomegalovirus Infection Mimics Manifestations of Underlying Diseases in Patients With Autoimmune Disorders: A Case Report and Literature Review. [PDF]

Immun Inflamm Dis
Autoimmune disorder patients are vulnerable to cytomegalovirus (CMV) infections, which can present with symptoms that mimic flare‐ups of the underlying disease. We present two cases: a 44‐year‐old woman with systemic lupus erythematosus and a 55‐year‐old man with sarcoidosis, both of whom developed unusual manifestations linked to CMV infection ...
Karimi E, Moradi Z, Soroureddin S, Nouri O, Tamartash Z, Kavosi H.   +5 more
europepmc   +2 more sources