Results 11 to 20 of about 5,811 (157)

Herpes Simplex Virus Hepatitis: An Overlooked Cause of Acute Liver Failure Across a Broad Spectrum of Immunocompromise. [PDF]

Liver Int
ABSTRACT Background and Aims Herpes simplex virus (HSV) infection is common worldwide, but hepatic involvement is rare. HSV hepatitis is an uncommon yet frequently catastrophic cause of acute hepatitis and acute liver failure (ALF), accounting for < 1% of ALF cases while carrying very high mortality when diagnosis and antiviral therapy are delayed ...
Mondelli MU, Ludovisi S, Di Matteo A, Şahin GÖ, Irving W, European Society of Clinical Microbiology and Infectious Diseases Study Group for Viral Hepatitis (ESGVH).   +5 more
europepmc   +2 more sources

The Troll Is Weakened but Not yet Defeated: An Update on Cytomegalovirus Management in Transplantation From the International CMV Symposium 2025. [PDF]

Transpl Infect Dis
This review synthesizes discussions from the 2025 International CMV Symposium on translating three recently updated international guidelines into clinical practice across solid organ and hematopoietic stem cell transplantation, highlighting advances in risk‐stratified prevention, emerging therapies, immune monitoring, and persistent implementation ...
Kotton CN, Sester M, Torre-Cisneros J, International CMV Symposium Faculty.   +3 more
europepmc   +2 more sources

At-Home Foscarnet Administration in Patients with Cytomegalovirus Infection Post-Allogeneic Stem Cell Transplantation: A Unicentric, Safe, and Feasible Program

Pharmaceuticals, 2023
Cytomegalovirus (CMV) infection is a relevant cause of morbimortality in patients receiving allogeneic stem cell transplantation (allo-HCT). Foscarnet (FCN) is an effective drug against CMV administered intravenously and usually on an inpatient basis ...
Sonia Ruiz-Boy, Alexandra Pedraza, Marta Prat, Maria Queralt Salas, Esther Carcelero, Gisela Riu-Viladoms, María Suárez-Lledó, Inés Monge-Escartín, Luis Gerardo Rodríguez-Lobato, Alexandra Martínez-Roca, Montserrat Rovira, Carmen Martínez, Cristina Gallego, Álvaro Urbano-Ispizua, Joan Sánchez, María Ángeles Marcos, Francesc Fernández-Avilés   +16 more
doaj   +1 more source

Kyrieleis Arteriolitis Associated with Acute Retinal Necrosis Due to Herpes Simplex Virus Type 1 Secondary to Herpetic Encephalitis

Vision, 2022
We report the case of a 52-year-old woman who presented to the emergency department with acute retinal necrosis in her left eye secondary to herpes simplex virus type 1 encephalitis for which she had been hospitalized four months before.
Olga E. Makri, Iasonas K. Tsekouras, Leonidia Leonidou, Konstantinos Kagkelaris, Vassilios Kozobolis, Constantinos D. Georgakopoulos   +5 more
doaj   +1 more source

Comparison of intravitreal ganciclovir monotherapy and combination with foscarnet as initial therapy for cytomegalovirus retinitis [PDF]

International Journal of Ophthalmology, 2018
AIM: To compare the effectiveness between multiple intravitreal injections of ganciclovir alone and combined with foscarnet as initial treatment for patients with newly-onset cytomegalovirus retinitis (CMVR). METHODS: The retrospective study observed 37
Jing-Jing Fan, Yong Tao, De-Kuang Hwang
doaj   +1 more source

Validated Modernized Assay for Foscarnet in Pharmaceutical Formulations Using Suppressed Ion Chromatography Developed through a Quality by Design Approach

Separations, 2021
Inspired by the United States Pharmacopoeia (USP) “monograph modernization” initiative, we developed and validated an assay for foscarnet sodium injection solution (“foscavir”), following quality by design (QbD) principles, incorporating design of ...
Ngoc Phuoc Dinh, Adel Shamshir, Gjani Hulaj, Tobias Jonsson   +3 more
doaj   +1 more source

Foscarnet-induced genital lesions: An overview with a case report

Dermatology Reports, 2018
Foscarnet is an important antiviral medication used mainly in the treatment of complicated Herpes-simplex virus and cytomegalovirus (CMV) infections. Reported first in the 1990’s, genital ulcers are a potential side effect in about 10% of cases.
Jonas A. Adalsteinsson, Michael Pan, Shivani Kaushik, Jonathan Ungar   +3 more
doaj   +1 more source

Analysis of cytomegalovirus resistance mutations and clinical features of CMV infection in immunocompromised children [PDF]

Клиническая микробиология и антимикробная химиотерапия
Objective. To determine frequency and spectrum of cytomegalovirus (CMV) resistance mutations to antiviral drugs in immunocompromised children. To study clinical course of resistant CMV infection in this patient population. Materials and Methods. This
Kozhushnaya O.S., Voropaev A.D., Levin P.A., Novichkova G.A., Solopova G.G.   +4 more
doaj   +1 more source

Successful Treatment of Epstein-Barr Virus-Induced Necrotizing Retinitis with Intravitreous Ganciclovir, Foscarnet, and Methotrexate

Case Reports in Ophthalmology, 2022
This is a report of an immunocompromised 49-year-old renal transplant patient with Epstein-Barr virus (EBV)-induced necrotizing retinitis (NR). The patient with NR underwent diagnostic vitrectomy.
Junsang Cho, Abdhish R. Bhavsar, Daniel H. Cho, Victoria Sattarova, Anne S. Abel, Rebecca Zadroga   +5 more
doaj   +1 more source

Brincidofovir Use after Foscarnet Crystal Nephropathy in a Kidney Transplant Recipient with Multiresistant Cytomegalovirus Infection

Case Reports in Transplantation, 2017
Background. Cytomegalovirus (CMV) antiviral drug resistance constitutes an increasing challenge in transplantation. Foscarnet is usually proposed when resistance for ganciclovir is suspected, but its use is limited by its nephrotoxicity.
Romain Vial, Christine Zandotti, Sophie Alain, Alexandre Decourt, Noémie Jourde-Chiche, Raj Purgus, Charleric Bornet, Laurent Daniel, Valérie Moal, Tristan Legris   +9 more
doaj   +1 more source