Results 31 to 40 of about 6,386 (141)

Cytomegalovirus Infection Mimics Manifestations of Underlying Diseases in Patients With Autoimmune Disorders: A Case Report and Literature Review

Immunity, Inflammation and Disease, Volume 14, Issue 3, March 2026.
Autoimmune disorder patients are vulnerable to cytomegalovirus (CMV) infections, which can present with symptoms that mimic flare‐ups of the underlying disease. We present two cases: a 44‐year‐old woman with systemic lupus erythematosus and a 55‐year‐old man with sarcoidosis, both of whom developed unusual manifestations linked to CMV infection ...
Elaheh Karimi, Zahra Moradi, Somayeh Soroureddin, Ozra Nouri, Zahra Tamartash, Hoda Kavosi   +5 more
wiley   +1 more source

Foscarnet calcium microcrystals as the intravitreal drug depot

, 2017
Injectable foscarnet calcium microcrystals can maintain the intravitreal drug concentration for months.
Yuling Sun, Yanbin Huang, Yong Tao, Qingchen Cao   +3 more
core   +1 more source

Preparation, characterization and in vitro antiviral activity evaluation of foscarnet-chitosan nanoparticles [PDF]

, 2014
A new nanoparticulate system for foscarnet delivery was prepared and evaluated. Nanoparticles were obtained by ionotropic gelation of chitosan induced by foscarnet itself, acting as an ionotropic agent in a manner similar to tripolyphosphate anion.
Donalisio, Manuela, Valeria Cagno, RUSSO, ELEONORA, Cagno, Valeria, CAVIGLIOLI, GABRIELE, GAGLIANONE, NOEMI, PARODI, BRUNELLA, BALDASSARI, SARA, Lembo, David, David Lembo, CAFAGGI, SERGIO, Manuela Donalisio, ZIBANA, CAMILLA   +12 more
core   +1 more source

Varicella Zoster Virus Infection: Clinical Features, Molecular Pathogenesis, Treatment, and Prevention

MedComm, Volume 7, Issue 3, March 2026.
This review focuses on the clinical features, molecular mechanisms, treatment methods, and preventive measures of the VZV, with the aim of providing a theoretical basis for the development of new treatment and prevention methods for HZ. ABSTRACT Varicella zoster virus (VZV) is a ubiquitous human herpesvirus that establishes lifelong latency and causes ...
Lei Peng, Honghao Song, Tianying Li, Yuqing Ma, Chen Yan, Yuhan Cao, Kaiqiang Sun, Chaofeng Han, Hongbin Yuan   +8 more
wiley   +1 more source

Treatment of Refractory Acute Retinal Necrosis with Intravenous Foscarnet or Cidofovir

, 2018
Purpose: To report use of intravenous foscarnet or cidofovir for the treatment of refractory acute retinal necrosis (ARN). Methods: Retrospective chart review. Results: Four immunocompetent men aged 45-90 years presented with ARN from 2008-2014.
Durand, Marlene L., Tobin, Ellis H., Kim, Ivana K., Barshak, Miriam B., Scott, Nathan L., Mali, Joshua O., Young, Lucy H., Stryjewski, Tomasz P., Foster, C. Stephen   +8 more
core   +1 more source

Effect of foscarnet therapy on human immunodeficiency virus p24 antigen levels in aids patients with cytomegalovirus retinitis

, 1992
Circulating human immunodeficiency virus (HIV) p24 antigen levels were measured in 22 AIDS patients who had detectable serum antigen at baseline after induction and maintenance therapy of foscarnet for cytomegalovirus retinitis in phase I/II multicenter ...
G. F. McKinley, C. M. van der Horst, R. B. Davis, McKinley, George F., DAVIS, R. B, M. A. Jacobson, HOOTON, T. M, Parenti, David M., VAN DER HORST, C. M, JACOBSON, M. A, M. M. Reddy, Grieco, Michael H., Reddy, Mohan M., CAUSEY, D. M, Davis, Roger B., Causey, Dennis M., Hooton, Thomas M., PARENTI, D. M, Jacobson, Mark A., D. M. Parenti, D. M. Causey, MCKINLEY, G. F, T. M. Hooton, REDDY, M. M, van der Horst Charles, M., GRIECO, M. H, M. H. Grieco   +26 more
core   +1 more source

HHV‐8/KSHV in Solid Organ Transplantation: Current Gaps of Knowledge and Future Directions

Transplant Infectious Disease, Volume 28, Issue 2, March/April 2026.
Risk mitigation strategies, including donors/recipients screening, DNAemia monitoring in recipients at risk, CNI‐to‐mTOR inhibitors switch, antivirals, and rituximab for KICS, may mitigate the impact of HHV‐8/KSHV infection in SOT. This review provides an update on KICS, identifies research gaps, and summarizes advances in screening and management ...
Alessandra Mularoni, Andrea Cona, Malgorzata Mikulska, Francesca Pecoraro, Carlotta Piazza, Elda De Vita, Giada Pietrosi, Matteo Bulati, Tiziana Lazzarotto, Mario Luppi   +9 more
wiley   +1 more source

Phenotypic characterisation of cytomegalovirus DNA polymerase: a method to study cytomegalovirus isolates resistant to foscarnet

, 2005
International audienceA phenotypic method was developed to test mutations in the human cytomegalovirus (HCMV) DNA polymerase gene (UL54) suspected to confer resistance to foscarnet. This method was used to determine the biochemical phenotype of wild-type
A.M. Fillet, Mazeron, Marie-Christine, M.C. Mazeron, Petit, Françoise, M.J. Sanson Le Pors, Alain, Sophie, A. Ducancelle, F. Petit, Gravisse, Jérôme, J. Gravisse, Fillet, Anne-Marie, S. Alain, Ducancelle, Alexandra, Pors, Marie-José Sanson Le   +13 more
core   +1 more source

Comparison of intravitreal ganciclovir monotherapy and combination with foscarnet as initial therapy for cytomegalovirus retinitis [PDF]

, 2018
AIM: To compare the effectiveness between multiple intravitreal injections of ganciclovir alone and combined with foscarnet as initial treatment for patients with newly-onset cytomegalovirus retinitis (CMVR). METHODS: The retrospective study observed 37
Jing-Jing Fan, Yong Tao, De-Kuang Hwang
core   +1 more source

Conformational states of HIV-1 reverse transcriptase for nucleotide incorporation vs. pyrophosphorolysis – binding of foscarnet [PDF]

, 2016
HIV-1 reverse transcriptase (RT) catalytically incorporates individual nucleotides into a viral DNA strand complementing an RNA or DNA template strand; the polymerase active site of RT adopts multiple conformational and structural states while performing
Kalyan Das, Anita R. Maguire, Arnold, Eddy, Anita R. Maguire (1444246), Jan Balzarini, Das, Kalyan, Miller, Matthew T., Jan Balzarini (161754), Jeffrey J. DeStefano (13415), Matthew T. Miller, Kalyan Das (1338543), Eddy Arnold (380419), Maguire, Anita R., Matthew T. Miller (2818933), Balzarini, Jan, Jeffrey J. DeStefano, Eddy Arnold, DeStefano, Jeffrey J.   +17 more
core   +1 more source