Treatment of cytomegalovirus retinitis with an intraocular sustained-release ganciclovir implant [PDF]
The objective of this prospective study was to evaluate the efficacy and complications of the use of an intraocular sustained-release ganciclovir implant for the treatment of active cytomegalovirus (CMV) retinitis in AIDS patients. Thirty-nine eyes of 26
Belfort, Rubens Junior +1 more
core +3 more sources
Viral Retinitis following Intraocular or Periocular Corticosteroid Administration: A Case Series and Comprehensive Review of the Literature. [PDF]
Purpose: To describe viral retinitis following intravitreal and periocular corticosteroid administration. Methods: Retrospective case series and comprehensive literature review. Results: We analyzed 5 unreported and 25 previously published cases of viral
Brown, D.M. +8 more
core +1 more source
BackgroundHuman immunodeficiency virus type 1 reverse transcriptase (HIV-1 RT) forms stable ternary complexes in which RT is bound tightly at fixed positions on the primer-template (P/T). We have probed downstream interactions between RT and the template
Wiriya Rutvisuttinunt +2 more
doaj +1 more source
Unraveling Cytomegalovirus Drug Resistance in Transplant Patients by Targeting Deep Sequencing. [PDF]
ABSTRACT Drug‐resistant cytomegalovirus (CMV) poses a major clinical challenge in transplant recipients, leading to treatment failure and increased morbidity. This study applied a next‐generation sequencing (NGS) approach to identify antiviral resistance mutations (ARMs) in 71 samples from 68 CMV‐positive patients who had undergone hematopoietic stem ...
Alemán S +7 more
europepmc +2 more sources
HHV-6 in liver transplantation : A literature review [PDF]
Human herpesvirus 6 (HHV-6A and HHV-6B) can cause primary infection or reactivate from latency in liver transplant recipients, which can result in a variety of clinical syndromes, including fever, hepatitis, encephalitis and higher rates of graft ...
Lautenschlager, Irmeli +3 more
core +1 more source
Cytomegalovirus (CMV) infection is a common complication in patients undergoing hematopoietic stem cell transplantation (HSCT). Management of refractory CMV infections, especially in developing countries, can be challenging due to the limited ...
Alejandra Pando-Caciano +4 more
doaj +1 more source
Central nervous system infection following allogeneic hematopoietic stem cell transplantation [PDF]
Objective/backgroundHere, we described the clinical characteristics and outcomes of central nervous system (CNS) infections occurring after allogeneic hematopoietic stem cell transplantation (allo-HSCT) in a single institution over the previous 6 years ...
Antonini +26 more
core +2 more sources
Adoptive T-cell immunotherapy for ganciclovir-resistant CMV disease after lung transplantation [PDF]
Infections with cytomegalovirus (CMV) can induce severe complications after solid organ transplantation (SOT). The prognosis for ganciclovir-resistant CMV infection and disease is particularly poor.
Beagley, L. +6 more
core +1 more source
KSHV Targeted Therapy: An Update on Inhibitors of Viral Lytic Replication
Kaposi’s sarcoma-associated herpesvirus (KSHV) is the causative agent of Kaposi’s sarcoma, primary effusion lymphoma and multicentric Castleman’s disease.
Natacha Coen +3 more
doaj +1 more source
Phenotype standardization for drug-induced kidney disease. [PDF]
Drug-induced kidney disease is a frequent cause of renal dysfunction; however, there are no standards to identify and characterize the spectrum of these disorders.
Awdishu, Linda +8 more
core +2 more sources

