Results 51 to 60 of about 5,811 (157)

A Novel Modified Bu/Vp16/cy/Flu/Ara‐C Conditioning Regimen Enhances Outcomes for High‐Risk Acute Lymphoblastic Leukemia Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

Cancer Medicine, Volume 15, Issue 3, March 2026.
ABSTRACT Purpose Allogeneic hematopoietic stem cell transplantation (allo‐HSCT) effectively treats high‐risk acute lymphoblastic leukemia (ALL), yet challenges persist due to post‐transplant relapse and conditioning regimen toxicities. The determination of an appropriate preconditioning regimen is critical to improving patient outcomes.
Xiaoyan Zhao, Yifan Yao, Yan Sun, Ziwei Xu, Aiguo Liu, Xin Dong, Huafang Wang   +6 more
wiley   +1 more source

Real-World Comparison of Maribavir to Foscarnet for the Treatment of Cytomegalovirus in Solid Organ and Hematopoietic Stem Cell Transplant Recipients

Viruses
Cytomegalovirus (CMV) infection in solid organ transplant (SOT) and hematopoietic cell transplant (HCT) recipients may increase the risk of rejection or allograft dysfunction, other infection(s), and morbidity and mortality.
Lauren Ogawa, Chelsea Morinishi, Ashrit Multani, Pryce Gaynor, Omer E. Beaird, Christine Pham, Joanna M. Schaenman   +6 more
doaj   +1 more source

Use of Foscarnet Therapy for EBV Infection following Control of PTLD with Enhancement of Cellular Immunity in a Lung-Transplant Recipient

Journal of Transplantation, 2011
Posttransplant lymphoproliferative disorder (PTLD) is a serious complication following solid organ transplantation with an annual incidence rate of 3–5% in lung-transplant recipients.
Kamyar Afshar, A. Purush Rao, Vipul Patel, Kevin Forrester, Sivagini Ganesh   +4 more
doaj   +1 more source

Cytomegalovirus Infection Mimics Manifestations of Underlying Diseases in Patients With Autoimmune Disorders: A Case Report and Literature Review

Immunity, Inflammation and Disease, Volume 14, Issue 3, March 2026.
Autoimmune disorder patients are vulnerable to cytomegalovirus (CMV) infections, which can present with symptoms that mimic flare‐ups of the underlying disease. We present two cases: a 44‐year‐old woman with systemic lupus erythematosus and a 55‐year‐old man with sarcoidosis, both of whom developed unusual manifestations linked to CMV infection ...
Elaheh Karimi, Zahra Moradi, Somayeh Soroureddin, Ozra Nouri, Zahra Tamartash, Hoda Kavosi   +5 more
wiley   +1 more source

In Vivo Emergence of UL56 C325Y Cytomegalovirus Resistance to Letermovir in a Patient with Acute Myeloid Leukemia after Hematopoietic Cell Transplantation

Mediterranean Journal of Hematology and Infectious Diseases, 2019
CMV associated tissue-invasive disease is associated with a considerable risk of morbidity and mortality after allogeneic hematopoietic stem cell transplantation (HSCT). Recently, the terminase inhibitor letermovir (LMV) has been approved for prophylaxis
Jochen J Frietsch, Detlef Michel, Thomas Stamminger, Friederike Hunstig, Sebastian Birndt, Ulf Schnetzke, Sebastian Scholl, Andreas Hochhaus, Inken Hilgendorf   +8 more
doaj   +1 more source

Overcoming Resistance: A Comprehensive Review and Treatment Approach for Acyclovir-Resistant Herpes Simplex Keratitis

Journal of Current Ophthalmology
Purpose: To comprehensively review the treatment approach for acyclovir (ACV)-resistant herpes simplex keratitis (HSK). Methods: We thoroughly searched Web of Science, PubMed, and Scopus for relevant keywords and conducted this narrative review which ...
Arash Mirzaei, Sahel Soltani Shahgoli, Raghuram Kognati, Emine Esra Karaca, Kasra Cheraqpour, Farhaneh Alahyari, Deepak Shukla, Ali R. Djalilian, Mohammad Soleimani   +8 more
doaj   +1 more source

Cytomegalovirus infection in pediatric haploidentical stem cell transplantation

Hematology/Oncology and Stem Cell Therapy
Background: Human cytomegalovirus (CMV) is a major source of morbidity and mortality in pediatric hematopoietic stem cell transplantation (HSCT). CMV replication is mainly controlled by T-cell-mediated immunity.
Abdulrahman AlSweed, Suliman Aljumaah, Hawazen AlSaedi, Hibah Alruwaisan, Raghad Alhuthil, Sami Al-Hajjar   +5 more
doaj   +1 more source

Herpes zoster verrucoso em doentes com SIDA.

Acta Médica Portuguesa, 1997
The authors describe a case of disseminated Herpes-Zoster (VZV) in an HIV 1 positive patient with AIDS. Hyperkeratotic characteristics, acyclovir resistance and sensitivity to foscarnet of cutaneous lesions are the most important features of this example.
V Agusto, I Franca, K Mansinho, C Araújo, F Borges, J L Champalimaud, A Poiares-Baptista, C Martins, J L Ricardo   +8 more
doaj   +1 more source

Leflunomide in the Treatment of a Pseudotumoral Genital Herpes Simplex Virus Infection in an HIV Patient

Case Reports in Infectious Diseases, 2017
The patient is a 52-year-old African American man with a past medical history of HIV infection (on antiretroviral therapy, CD4 count 399 cells/µL, and undetectable HIV viral load) and recurrent genital herpes. While on valacyclovir, the patient presented
Marie R. Roger, Gregory M. Anstead
doaj   +1 more source

In vitro activity of six antiviral drugs against equid alphaherpesvirus type 1 indicates ganciclovir as promising drug for in vivo studies

Ciência Rural, 2018
: Equid alphaherpesvirus type 1 (EHV-1) is distributed worldwide and is a major agent of abortion, respiratory and neurological disease in horses. No specific treatment is available for EHV-1 infection, yet the potential of antiviral therapy has been ...
Amanda Lovato de Oliveira, Juliana Felipetto Cargnelutti, Ana Paula Gnocato Mortari, Eduardo Furtado Flores, Rudi Weiblen   +4 more
doaj   +1 more source