Results 41 to 50 of about 6,506 (212)

Plerixafor for pathogen‐agnostic treatment in murine thigh infection and zebrafish sepsis

Clinical and Translational Science
Plerixafor is a CXCR4 antagonist approved in 2008 by the FDA for hematopoietic stem cell collection. Subsequently, plerixafor has shown promise as a potential pathogen‐agnostic immunomodulator in a variety of preclinical animal models.
Martin O. Evans, Darren M. Smith, Adrian T. Kress, Robert J. Nadeau, Daniel J. Selig, Diana Caridha, Ratanachat Racharaks, Thomas Langowski, Michael S. Madejczyk, Chance Carbaugh, David Saunders, Mark Widder, Jason De Meese, Patricia J. Lee, Jesse P. DeLuca   +14 more
doaj   +1 more source

ProTides for Antiviral Activity Beyond Liver Cells

Chemistry – A European Journal, Volume 32, Issue 21, 1 June 2026.
A strategy for obtaining prodrugs of antiviral nucleotides with broad tissue activity is presented that relies on cycloalkyl or cycloalkylalkyl esters, improving uptake and esterase cleavage, and producing nanomolar inhibitors in kidney, colon, and lung cells.
Felix Goebel, Adrian Humboldt, Heeyoung Kim, Carl J. M. Schölzel, Ralf Bartenschlager, Clemens Richert   +5 more
wiley   +1 more source

3D model of DBL2X-CIDR double domain of VAR2CSA.

, 2019
(Left) Global view of the DBL2X-CIDR model in ribbon representation. (Right) Zoom on the T934 residue. Light blue, DBL2X domain; dark blue, ID2 or CIDR; pink, T934 side-chain represented as spheres (left) or ball and stick (right).
Christian Doerig (36626), Zaineb Fourati (565024), Florence Armand (832848), Sofia Nunes-Silva (6817673), Sébastien Dechavanne (230733), Benoît Gamain (230737), Stéphane Gangnard (240555), Marilou Tétard (6817664), Marc Moniatte (832849), Jose-Juan Lopez-Rubio (106848), Jean-Philippe Semblat (170283), Romain Hamelin (832847), Dominique Dorin-Semblat (832845), Aurélie Claës (6817667), Anand Srivastava (230731), Graziella Matesic (6817670), Artur Scherf (7392)   +16 more
core   +1 more source

Fertility after synchronization of estrus in dairy heifers using GnRH, PGF2a, and Progesterone (CIDR) [PDF]

, 2001
Our objective was to determine fertility of heifers after synchronization of estrus using PGF2", preceded by progesterone, GnRH, or both. Dairy heifers (n = 246) were assigned randomly to three treatments: 1) 50 :g of GnRH given 6 d before 25 mg of ...
Stevenson, Jeffrey S., Jeffrey S. Stevenson, A.M. Richardson, Hensley, B.A., B.A. Hensley, Richardson, A.M.   +5 more
core   +1 more source

Chameleonic Color‐Variable Microbead Emitters for Multilevel Spectroscopic Encryption from Visible to Infrared Wavelengths

Advanced Optical Materials, Volume 14, Issue 19, 22 May 2026.
Whispering‐gallery‐mode microresonators with sharp resonant peaks enable photonic barcoding. Similar to a chameleon, a rare‐earth‐free microcavity with π‐conjugated PAHs enables visibleto‐near infrared color generation from a single microbead. The unique resonat emission (spectral barcode) can be dynamically transformed via excitation wavelength change,
Barun Kumar Barman, Keisuke Watanabe, Kenzo Deguchi, Shinobu Ohki, Kenjiro Hashi, Atsushi Goto, Tadaaki Nagao   +6 more
wiley   +1 more source

Differences in neutralizing antibody sensitivities and envelope characteristics indicate distinct antigenic properties of Nigerian HIV-1 subtype G and CRF02_AG

Virology Journal
The magnitude of the HIV-1 epidemic in Nigeria is second only to the subtype C epidemic in South Africa, yet the subtypes prevalent in Nigeria require further characterization.
Lindsay Wieczorek, David Chang, Eric Sanders-Buell, Michelle Zemil, Elizabeth Martinez, Jesse Schoen, Agnes-Laurence Chenine, Sebastian Molnar, Brittani Barrows, Kultida Poltavee, Man E. Charurat, Alash’le Abimiku, William Blattner, Michael Iroezindu, Afoke Kokogho, Nelson L. Michael, Trevor A. Crowell, Julie A. Ake, Sodsai Tovanabutra, Victoria R. Polonis, on behalf of the AFRICOS and TRUST/RV368 Study Groups   +20 more
doaj   +1 more source

Estrous Synchronization in Peranakan Etawah Goat Using CIDR-G

, 2011
A study on the effectiveness on estrous synchronization using CIDR-G in peranakan etawah (PE) goat was conducted. Twenty-eight multiporous PE goats were randomly allocated to two groups (A & B) and CIDR was inserted for 16 days.
Syaefudin, Y, Sutama, I Ketut, Semiadi, G   +2 more
core   +1 more source

Fertility of heifers after synchronization of estrus using GnRH, PGF2α, and progesterone (CIDR) [PDF]

, 2002
Our objectives were to determine fertility of heifers after estrus synchronization using PGF2α preceded by either progesterone, GnRH, or both. Beef (n = 193) and dairy (n = 246) heifers were assigned randomly to three treatments: 1) 50 μg of GnRH and a ...
Stevenson, Jeffrey S., Jeffrey S. Stevenson, Marple, T.J., Johnson, Sandra K., A.M. Richardson, T.J. Marple, Hensley, B.A., Sandra K. Johnson, B.A. Hensley, Richardson, A.M.   +9 more
core   +1 more source

Synchronization of Estrus and Ovulation Using CIDR and Prostaglandin for Improving Pregnancy Rate of Repeat Breeder Egyptian Buffaloes [PDF]

Journal of Animal and Poultry Production, 2019
To synchronize estrus and ovulation for improving pregnancy rate (PR) of repeat-breeder buffaloes, Controlled Internal Drug Release (CIDR) + prostaglandin (PGF2α) was used before service of repeat breeder buffaloes.
E. EL-Emary, M. Fateh Hammad, W. Nagy, SH. Gabr, M. Abo-Farw   +4 more
doaj   +1 more source

Precursors of Marine Heatwaves in the Eastern Mediterranean

Geophysical Research Letters, Volume 53, Issue 8, 28 April 2026.
Abstract Re‐analysis and observational data are used to identify the relationship between marine heatwaves and atmospheric heatwaves over the Eastern Mediterranean, and also the precursors of marine heatwaves in the 15‐day before heatwave onset. There has been a clear tendency for more heat extremes in recent years.
Chaim I. Garfinkel, Sagi Knobler, Dan Liberzon, Gil Rilov   +3 more
wiley   +1 more source