Results 71 to 80 of about 440,670 (311)

Macrophage–Derived Ferritin Exacerbates Silica‐Induced Pulmonary Fibrosis via PIK3R2‐Mediated Fibroblast Differentiation

open access: yesAdvanced Science, EarlyView.
This study identifies ferritin as a pivotal mediator of silica‐induced pulmonary fibrosis. Macrophage‐derived ferritin drives fibroblast‐to‐myofibroblast differentiation via the PIK3R2/SMAD pathway, while ferritin knockdown alleviates fibrosis. These findings define ferritin as both a biomarker and pathogenic driver, highlighting ferritin‐PIK3R2 ...
Liqun Wang   +14 more
wiley   +1 more source

Development of excise rates criteria in the European Union and its member states fulfilment

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2009
European Union regulates member states market to secure free trade. This obtains also in case of excise imposed on cigarettes, which is a composite tax.
Petr David
doaj   +1 more source

Integrative Approaches to Treating Cellular Senescence in Kidney Disease

open access: yesAdvanced Science, EarlyView.
ABSTRACT Cellular senescence in the kidney plays a crucial role in the progression of acute kidney injury and chronic kidney disease. Therapeutic approaches targeting senescent cells, such as small molecule senolytic and senomorphic drugs, display efficacy in preclinical models.
Tomoka Misawa   +3 more
wiley   +1 more source

Macrophage Extracellular Traps in Immunity and Cancer

open access: yesAdvanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li   +5 more
wiley   +1 more source

Overview of methods for determining polycyclic aromatic hydrocarbons in cigarette smoke, ETHS and ENDS aerosole, liquids for ENDS

open access: yesНовые технологии, 2019
The problem of improving the quality and reducing the toxicity of tobacco products is relevant and directly related to health. In 2008 the Russian Federation joined the WHO FCTC (Framework Convention of the World Health Organization on Tobacco Control ...
T. A. Zaitseva
doaj   +1 more source

A High‐Performance and Fully Recyclable Supramolecular Nanofibrous Membrane for Multifunctional Air Filtration

open access: yesAdvanced Science, EarlyView.
A green, thermoreversible self‐assembly strategy yields a multifunctional and recyclable supramolecular nanofibrous membrane. Graphene oxide (GO) nanosheet acts as a heterogeneous nucleation‐templating agent, simultaneously modulating the supramolecular crystal packing while tailoring the nanofibrous architecture for elite performance.
Wenjing Sun   +6 more
wiley   +1 more source

The nature of changes in carbohydrate content of tobacco upon storage of cigarettes in different climatic conditions

open access: yesНовые технологии, 2019
Tobacco raw materials of various botanical, commercial varieties grown in different climatic conditions have significant differences in chemical composition.
I. M. Ostapchenko   +2 more
doaj   +1 more source

Post‐Translational Regulation of CD8+ T Cell Fate and Dysfunction in Tumor Immunity

open access: yesAdvanced Science, EarlyView.
This review delineates how post‐translational modifications (PTMs) function as a central regulatory interface governing CD8+ T cell activation, differentiation, persistence, and exhaustion in antitumor immunity. By integrating antigenic, metabolic, and microenvironmental cues, diverse PTM programs coordinate transcriptional and chromatin states that ...
Zihao Zhou   +8 more
wiley   +1 more source

Visionary Leadership in Cancer Care: An Interview With Professor Timothy J. Eberlein

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Professor Timothy J. Eberlein and Professor Ken Shirabe, President of the Japanese Society of Gastroenterological Surgery, during their interview discussing the vision, strategic framework, and leadership that shaped the development of the Siteman Cancer Center into a world‐class institution. ABSTRACT This is a short interview with Professor Timothy J.
Ken Shirabe   +3 more
wiley   +1 more source

Electronic cigarettes [PDF]

open access: yesThorax, 2013
Jennifer L, Reed   +2 more
openaire   +5 more sources

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