CIGB-258, a peptide derived from human heat-shock protein 60, decreases hyperinflammation in COVID-19 patients. [PDF]
Cell Stress Chaperones, 2021 Hyperinflammation distinguishes COVID-19 patients who develop a slight disease or none, from those progressing to severe and critical conditions. CIGB-258 is a therapeutic option for the latter group of patients. This drug is an altered peptide ligand (APL) derived from the cellular stress protein 60 (HSP60).
Hernandez-Cedeño M +8 more
europepmc +5 more sources
CIGB-258 immunomodulatory peptide for the treatment of critical and severe COVID-19 patients
Revista Cubana de Medicina Militar, 2020 Introduction: CIGB-258 is an immunomodulatory peptide with anti-inflammatory properties. Objectives: To establish the therapeutic schedule with CIGB-258 peptide for COVID-19 critically ill patients.
Rafael Venegas Rodríguez +14 more
doaj +3 more sources
CIGB-258, péptido inhibidor de la hiperinflamación en pacientes con COVID-19
Anales de la Academia de Ciencias de Cuba, 2022 Introducción. El CIGB-258 es un péptido, cuyo mecanismo de acción se ha asociado con la inhibición de la inflamación. El presente trabajo tiene como objetivo demostrar que el CIGB-258 reduce la hiperinflamación en los pacientes con COVID-19. Métodos.
María del Carmen Domínguez Horta +12 more
doaj +1 more source
Péptido inmumodulador CIGB-258 para el tratamiento de pacientes graves y críticos con la COVID-19 [PDF]
Revista Cubana de Medicina Militar, 2020 Introducción: El CIGB-258 es un péptido inmunomodulador con propiedades antiinflamatorias. Objetivos: Establecer la frecuencia de dosis y el tiempo de tratamiento con el péptido CIGB-258, para pacientes críticos con la COVID-19.
Ariana García +14 more
core +3 more sources
CIGB-258 immunomodulatory peptide: a novel promising treatment for critical and severe COVID-19 patients [PDF]
, 2020 This study characterizes the first clinical application of CIGB-258 in COVID-19 patients. CIGB-258 is an immunoregulatory peptide, derived from the cellular heat shock protein 60 (HSP60).
A Garcia +15 more
core +2 more sources
Tratamiento con antiinflamatorios en paciente de alto riesgo Covid 19, evolución de la enfermedad, presentación de caso clínico [PDF]
, 2022 On March 11, 2020, covid 19 was considered a pandemic by the WHO, that same day the first case in Cuba is confirmed from an Italian tourist. In the province of Las Tunas during the month of August there is a deliberate increase in the number of cases ...
Cruz Fernández, Elider +2 more
core +2 more sources
Cuba’s response to COVID-19: lessons for the future [PDF]
, 2021 Purpose The purpose of this paper is to examine the relevance of Cuba’s medical system, its health tourism and related diplomacy in the context of the recent COVID-19 pandemic for the global response to disease outbreaks.
Wylie LL
core +1 more source
The global response to the COVID-19 pandemic: how have immunology societies contributed? [PDF]
, 2020 The COVID-19 pandemic is shining a spotlight on the field of immunology like never before. To appreciate the diverse ways in which immunologists have contributed,Nature Reviews Immunologyinvited the president of the International Union of Immunological ...
Akbar, Arne N +28 more
core +5 more sources
Consideraciones sobre la atención a los adultos mayores durante la COVID-19 en Cuba [PDF]
, 2022 El envejecimiento es el proceso gradual que se desarrolla durante el curso de la vida y que conlleva cambios biológicos, fisiológicos, psicosociales y funcionales de variadas consecuencias.
Sosa García, Danay
core +1 more source
Protocolos de tratamiento a la COVID-19: aproximación desde una perspectiva farmacoterapéutica [PDF]
, 2022 La introducción de los protocolos y guías de actuación clínica en los contextos sanitarios ha jugado un papel esencial en el combate a la COVID-19. Es por ello que el presente trabajo muestra los resultados derivados de una revisión narrativa realizada ...
Astorga González, Beatriz +1 more
core +2 more sources