Results 21 to 30 of about 875 (174)

Synthesis of the A-F Fragment of the Pacific Ciguatoxin CTX3C by Iterative Ring-Closing Metathesis and Tsuji-Trost Allylation. [PDF]

Chemistry, 2023
The fully functionalized A−F ring system of the Pacific ciguatoxin CTX3C suitable for coupling to the I−M fragment of the natural product, has been synthesized from a simple glucal derivative. A six‐step sequence that features ring‐closing metathesis and stereoselective palladium‐mediated allylation has been deployed in an iterative manner to construct
Triantafyllakis M, Alexander S, Woolford S, Wilson C, Clark JS.   +4 more
europepmc   +2 more sources

Faster ciguatoxin extraction methods for toxicity screening [PDF]

Scientific Reports
Ciguatera poisoning (CP) is a severe global public health problem caused by the consumption of seafood products contaminated with ciguatoxins (CTXs). The growing demand for seafood products requires high-throughput testing for CTX-susceptible seafood ...
Christopher R. Loeffler, Astrid Spielmeyer   +1 more
doaj   +2 more sources

Toxicity Screening of a Gambierdiscus australes Strain from the Western Mediterranean Sea and Identification of a Novel Maitotoxin Analogue

Marine Drugs, 2021
Dinoflagellate species of the genera Gambierdiscus and Fukuyoa are known to produce ciguatera poisoning-associated toxic compounds, such as ciguatoxins, or other toxins, such as maitotoxins.
Pablo Estevez, David Castro, José Manuel Leão-Martins, Manoëlla Sibat, Angels Tudó, Robert Dickey, Jorge Diogene, Philipp Hess, Ana Gago-Martinez   +8 more
doaj   +1 more source

Ciguatoxin-Producing Dinoflagellate Gambierdiscus in the Beibu Gulf: First Report of Toxic Gambierdiscus in Chinese Waters

Toxins, 2021
Ciguatera poisoning is mainly caused by the consumption of reef fish that have accumulated ciguatoxins (CTXs) produced by the benthic dinoflagellates Gambierdiscus and Fukuyoa.
Yixiao Xu, Xilin He, Wai Hin Lee, Leo Lai Chan, Douding Lu, Pengbin Wang, Xiaoping Tao, Huiling Li, Kefu Yu   +8 more
doaj   +1 more source

Characterisation of ciguatoxins

EFSA Supporting Publications, 2021
The primary objective of this specific grant was to characterize the risk associated to Ciguatera Poisoning (CP) in the EU by developing a sensitive methodology of LC-MS/MS. The preparation of reference materials including the main ciguatoxins (CTXs) responsible for the contamination was considered the secondary objective to facilitate the ...
Gago‐martinez, A., Leão, J.m., Estevez, P., Castro, D., Barrios, C., Hess, Philipp, Sibat, Manoella   +6 more
openaire   +2 more sources

Critical Review and Conceptual and Quantitative Models for the Transfer and Depuration of Ciguatoxins in Fishes

Toxins, 2021
We review and develop conceptual models for the bio-transfer of ciguatoxins in food chains for Platypus Bay and the Great Barrier Reef on the east coast of Australia.
Michael J. Holmes, Bill Venables, Richard J. Lewis   +2 more
doaj   +1 more source

An Extensive Survey of Ciguatoxins on Grouper Variola louti from the Ryukyu Islands, Japan, Using Liquid Chromatography–Tandem Mass Spectrometry (LC-MS/MS)

Journal of Marine Science and Engineering, 2022
Ingesting fish contaminated with ciguatoxins (CTXs) originating from epibenthic dinoflagellates causes ciguatera fish poisoning (CFP). CFP occurs mainly in the tropical and subtropical Indo–Pacific region and the Caribbean Sea.
Naomasa Oshiro, Hiroya Nagasawa, Miharu Watanabe, Mio Nishimura, Kyoko Kuniyoshi, Naoki Kobayashi, Yoshiko Sugita-Konishi, Hiroshi Asakura, Katsunori Tachihara, Takeshi Yasumoto   +9 more
doaj   +1 more source

Asynchrony of Gambierdiscus spp. Abundance and Toxicity in the U.S. Virgin Islands: Implications for Monitoring and Management of Ciguatera

Toxins, 2021
Ciguatera poisoning (CP) poses a significant threat to ecosystem services and fishery resources in coastal communities. The CP-causative ciguatoxins (CTXs) are produced by benthic dinoflagellates including Gambierdiscus and Fukuyoa spp., and enter reef ...
Justin D. Liefer, Mindy L. Richlen, Tyler B. Smith, Jennifer L. DeBose, Yixiao Xu, Donald M. Anderson, Alison Robertson   +6 more
doaj   +1 more source

The Occurrence, Distribution, and Toxicity of High-Risk Ciguatera Fish Species (Grouper and Snapper) in Kiritimati Island and Marakei Island of the Republic of Kiribati

Toxins, 2022
Ciguatera is one of the most widespread food poisonings caused by the ingestion of fish contaminated by ciguatoxins (CTXs). Snapper and grouper with high palatable and economic value are the primary food source and fish species for exportation in the ...
Jingyi Zhu, Wai-Hin Lee, Jiajun Wu, Shiwen Zhou, Ki-Chun Yip, Xiaowan Liu, Taratau Kirata, Leo-Lai Chan   +7 more
doaj   +1 more source

Cardiovascular complications in ciguatera fish poisoning: A wake-up call

Heart Views, 2011
Ciguatera fish poisoning occurs with ingestion of fish containing ciguatoxin. It causes a clinical syndrome that comprises classic gastrointestinal, neurological and cardiovascular symptoms.
Subramanian Senthilkumaran, Ramachandran Meenakshisundaram, Andrew D Michaels, Ponnuswamy Suresh, Ponniah Thirumalaikolundusubramanian   +4 more
doaj   +1 more source