Results 31 to 40 of about 13,123 (191)

O RISCO COMO NOVO PARADIGMA DA HUMANIDADE – MERGULHO EM ALGUMAS QUESTÕES RENOVADAS (E LATERAIS) DA “SOCIEDADE DO RISCO”

Revista de Estudos Jurídicos da UNESP, 2015
Hoje, mais do que nunca, vivemos numa sociedade hipercomplexa, de catástrofes causadas pela mão do Homem, imprevisíveis, resultantes de decisões humanas e de consequências aterradoras.
Paulo Silva Fernandes
doaj   +1 more source

Dexamethasone Preconditioning Improves the Response of Collagen-Induced Arthritis to Treatment with Short-Term Lipopolysaccharide-Stimulated Collagen-Loaded Dendritic Cells

Clinical and Developmental Immunology, 2013
Background. Pharmacologically modulated dendritic cells (DCs) have been shown to restore tolerance in type II collagen-(CII-) induced arthritis (CIA). We examined the effect of dexamethasone (DXM) administration as a preconditioning agent, followed by an
Corina Peña, David Gárate, Juan Contreras-Levicoy, Octavio Aravena, Diego Catalán, Juan C. Aguillón   +5 more
doaj   +1 more source

CII-data.xlsx

, 2019
CII is a dimensionless structural variable to predict canopy water storage capacity. This data can be used to validate the potential of CII to predict canopy water storage capacity, as well as used to compare with other structural ...
Yue Yu (6901409)
core   +1 more source

Coupling of the expression of proliferation and epithelialmesenchymal transition markers with the histidine-rich glycoprotein HRG mRNA expression in breast diseases

Сибирский научный медицинский журнал
Non-malignant breast diseases (NMBD) may increase the risk of developing a malignant neoplasm. Therefore, it seems relevant to search for criteria for cell malignancy in NMBD.
S. А. Arkhipov, А. А. Studenikina, V. V. Arkhipova, А. V. Proskura, А. I. Autenshlyus   +4 more
doaj   +1 more source

Humoral autoimmune response against specific collagen type II epitopes in Bulgarian patients with rheumatoid arthritis [PDF]

Journal of BioScience and Biotechnology, 2016
Collagen type II (CII) is a strong candidate autoantigen for rheumatoid arthritis (RA) pathogenesis. CII is the main structural protein of synovial cartilage and it is attacked by both antibodies and T-cells during RA disease course.
Tsvetelina Batsalova, Petya Ivanova, Plamka Antova, Balik Dzhambazov   +3 more
doaj  

Hydroxyl radical modification of collagen type II increases its arthritogenicity and immunogenicity.

PLoS ONE, 2012
BackgroundThe oxidation of proteins by endogenously generated free radicals causes structural modifications in the molecules that lead to generation of neo-antigenic epitopes that have implications in various autoimmune disorders, including rheumatoid ...
Uzma Shahab, Saheem Ahmad, Moinuddin, Kiran Dixit, Safia Habib, Khursheed Alam, Asif Ali   +6 more
doaj   +1 more source

Cerium Nanoparticle‐Mediated Inhibition of the NSUN2/m5C Axis Suppresses Synovial Aggression in Rheumatoid Arthritis

Advanced Science, EarlyView.
A novel epitranscriptomic mechanism in rheumatoid arthritis is uncovered: NSUN2 promotes disease via m5C‐dependent stabilization of ICMT mRNA, fueling the migration and invasion of pathogenic RA FLS. Targeting this axis with engineered nanoparticles (Ce/SAA NPs) effectively inhibits disease progression, presenting a precise therapeutic strategy ...
Ruiru Li, Simin Chen, Huijuan Hu, Shiyao Wu, Jingnan Wang, Kai Sun, Chenxi Peng, Suling Liu, Shuoyang Zhang, Yu Kuang, Wei Chen, Qian Qiu, Liuqin Liang, Yu Wen, Hanshi Xu, Youjun Xiao   +15 more
wiley   +1 more source

Hysteresis and bistability in the succinate-CoQ reductase activity and reactive oxygen species production in the mitochondrial respiratory complex II

Redox Biology, 2020
The mitochondrial respiratory Complex II (CII) is one of key enzymes of cell energy metabolism, linking the tricarboxylic acid (TCA) cycle and the electron transport chain (ETC).
Nikolay I. Markevich, Miliausha H. Galimova, Lubov N. Markevich   +2 more
doaj   +1 more source

FaHSP17.8-CII orchestrates lead tolerance and accumulation in shoots via enhancing antioxidant enzymatic response and PSII activity in tall fescue

Ecotoxicology and Environmental Safety, 2021
Tall fescue (Festuca arundinacea Schreb.) shows huge potential for lead (Pb) phytoremediation, while little is known on the molecular mechanisms involved in Pb tolerance and accumulation. Here, genetic engineering strategy was firstly used to investigate
Tao Wang, Maurice Amee, Guangyang Wang, Yan Xie, Tao Hu, Huawei Xu   +5 more
doaj   +1 more source

Radical‐Mediated In Situ Fluorescence Dye Deposition: A Simple Interfacial Signal Amplification Reaction for Ultrasensitive Immunoassay on Barcode Beads

Advanced Science, EarlyView.
A radical‐mediated in situ fluorescence dye deposition (RIFD) reaction containing merely three elements of beads, dyes, and radicals is discovered for the first time, and its underlying mechanism is elucidated. This simple RIFD enables the interfacial and ultrafast deposition of free dyes onto barcode beads, serving as a powerful signal amplification ...
Jiayu Zhang, Yao Wang, Xinyi Huang, Haiyu Wu, Qiuning Lin, Hongchen Gu, Li Jiang, Linyong Zhu, Hong Xu   +8 more
wiley   +1 more source