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Innovative Clinical Perspectives for CIK Cells in Cancer Patients [PDF]
Cytokine-induced killer (CIK) cells are T lymphocytes that have acquired, in vitro, following extensive manipulation by Interferon gamma (IFN-γ), OKT3 and Interleukin 2 (IL-2) addition, the expression of several Natural Killer (NK) cell-surface markers.
Martino Introna
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Cancer Immunology, Immunotherapy, 2020
Adjuvant cytokine-induced killer (CIK) cell immunotherapy has shown potential in improving the prognosis of hepatocellular carcinoma (HCC) patients after curative resection. However, whether an individual could obtain survival benefit from CIK cell treatment remains unknown. In the present study, we focused on the characteristics of CIK cells and aimed
Qing Liu, Jian-Chuan Xia, Qiuzhong Pan
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Adjuvant cytokine-induced killer (CIK) cell immunotherapy has shown potential in improving the prognosis of hepatocellular carcinoma (HCC) patients after curative resection. However, whether an individual could obtain survival benefit from CIK cell treatment remains unknown. In the present study, we focused on the characteristics of CIK cells and aimed
Qing Liu, Jian-Chuan Xia, Qiuzhong Pan
exaly +3 more sources
Journal of Cancer Research and Clinical Oncology, 2014
Cytokine-induced killer (CIK) cells represent an exceptional T cell population uniting a T cell and natural killer cell like phenotype in their terminally differentiated CD3(+)CD56(+) subset, which features non-MHC-restricted tumor-killing activity. CIK cells are expandable from peripheral blood mononuclear cells and mature following the addition of ...
Leonard Christopher Schmeel +2 more
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Cytokine-induced killer (CIK) cells represent an exceptional T cell population uniting a T cell and natural killer cell like phenotype in their terminally differentiated CD3(+)CD56(+) subset, which features non-MHC-restricted tumor-killing activity. CIK cells are expandable from peripheral blood mononuclear cells and mature following the addition of ...
Leonard Christopher Schmeel +2 more
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DC-CIK as a widely applicable cancer immunotherapy
Expert Opinion on Biological Therapy, 2020Introduction: Immunotherapy is now a standard treatment for many malignancies. Although immune checkpoint inhibition has demonstrated substantial efficacy by enhancing T cell activation and function in the tumor microenvironment, adoptive transfer of T and NK cell products promises to provide activated cells capable of immediate and direct tumor ...
Jun Ren, Shuo Wang, Herbert Kim Lyerly
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Clinical trials on CIK cells: first report of the international registry on CIK cells (IRCC)
Journal of Cancer Research and Clinical Oncology, 2010Recently, a subset of natural killer T lymphocytes termed "cytokine-induced killer (CIK) cells" has been described. To build an international registry, we collected the clinical data and treatment of patients with cancer using CIK cells from the literature and the respective investigators.
C, Hontscha +4 more
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Nature Plants, 2018
The stem cell niche in plant shoots is maintained by carefully orchestrated feedback between a series of CLAVATA (CLV) receptors and their ligand CLV3, and the transcription factor WUSCHEL. A new clade of co-receptors, CLV3-insensitive receptor kinases (CIKs), provides an important missing link in CLV signalling.
Fang, Xu, David, Jackson
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The stem cell niche in plant shoots is maintained by carefully orchestrated feedback between a series of CLAVATA (CLV) receptors and their ligand CLV3, and the transcription factor WUSCHEL. A new clade of co-receptors, CLV3-insensitive receptor kinases (CIKs), provides an important missing link in CLV signalling.
Fang, Xu, David, Jackson
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Canadian Theatre Review, 1997
Caution: Copyright 1997 by Rachael Van Fossen and Darrel Wildcat. This play is fully protected under the copyright laws of Canada and all other countries of the Copyright Union. Changes to the script are expressly forbidden without the written consent of Darrel Wildcat and Rachael Van Fossen.
Rachael Van Fossen, Darrel Wildcat
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Caution: Copyright 1997 by Rachael Van Fossen and Darrel Wildcat. This play is fully protected under the copyright laws of Canada and all other countries of the Copyright Union. Changes to the script are expressly forbidden without the written consent of Darrel Wildcat and Rachael Van Fossen.
Rachael Van Fossen, Darrel Wildcat
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Security Analysis of CIKS-128 and CIKS-128H Using Key Schedule Weaknesses
International Symposium on Computer Science and its Applications, 2008In this paper, we show that CIKS-128 and CIKS-128H are vulnerable to related-key differential attacks. We first describe how to construct their full-round related-key differential characteristics with high probabilities and then we exploit them to break the full-round CIKS-128 and CIKS-128H with 244,and 248 data and time complexities, respectively ...
Changhoon Lee +5 more
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Related-Key Attacks on DDP Based Ciphers: CIKS-128 and CIKS-128H
2004CIKS-128 and CIKS-128H are 128-bit block ciphers with a 256-bit key sizes based on data-dependent operations, respectively. They are also fast hardware-oriented ciphers and improvements of block cipher CIKS-1 introduced in [14]. This paper presents related-key differential attacks on full-round CIKS-128 and CIKS-128H.
Youngdai Ko +4 more
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A Novel Algorithm for Generating GVKEY-CIK Link Table
SSRN Electronic Journal, 2020ABSTRACT This paper presents a do-it-yourself algorithm to generate the historical GVKEY-CIK link table. The proposed algorithm features a technique of pre-classifying sample data into different treatment subgroups and utilizing historical firm information available from the source data to increase (reduce) matching efficiency (errors ...
K. C. Kenneth Chu +2 more
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