Results 61 to 70 of about 12,794 (204)

Decrease in the effectiveness of valproic acid against the background of antibacterial therapy with imipenem/cilastatin in pediatric practice: A case report

Сибирский научный медицинский журнал
A clinical case of the co-medication of valproic acid and cilastatin/imipenem in a 17-year-old girl with generalized tonic-clonic seizures is described.
A. B. Strok, M. S. Chenkurov, M. N. Kostyleva, D. A. Umutkuzina   +3 more
doaj   +1 more source

Lemierre's Syndrome Caused by Klebsiella pneumoniae: Case Report and Review of the Literature

Clinical Case Reports, Volume 14, Issue 2, February 2026.
Axial contrast‐enhanced chest CT demonstrating multiple peripheral cavitary nodules and consolidations, predominantly in the right lower lobe, consistent with septic pulmonary emboli (arrows). ABSTRACT Klebsiella pneumoniae is an uncommon but increasingly recognized cause of Lemierre's syndrome, a condition classically associated with Fusobacterium ...
Abril Aguilar Guerrero, Eduardo Porras Rosales   +1 more
wiley   +1 more source

Comparative efficacies of imipenem, oxacillin and vancomycin for therapy of chronic foreign body infection due to methicillin-susceptible and -resistant Staphylococcus aureus [PDF]

, 2017
The efficacies of imipenem when directed against methicillin-susceptible (MSSA) and methicillin-resistant (MRSA) strains of Staphylococcus aureus were compared with those of oxacillin and vancomycin in a subcutaneous rat model, using chronically infected
Chuard, Christian, Lew, Daniel P., Rohner, Peter, Schaad, Heinz J., Vaudaux, Pierre, Waldvogel, Francis A.   +5 more
core  

Septic Shock Caused by Coinfection of Shewanella algae Bloodstream Infection and Epstein‐Barr Virus: Clinical Characteristics and Genomic Analysis

MicrobiologyOpen, Volume 15, Issue 1, February 2026.
This study reports a septic shock case in inland China caused by coinfection of Shewanella algae bloodstream infection and Epstein‐Barr virus. Genomic analysis revealed freshwater adaptation of the strain via unique genes for transporters and carbohydrate‐active enzymes.
Jianmei Chen, Dong Ling, Feng Wang, Liping Liu, Yucheng Ren, Chengying Chen, Na Su   +6 more
wiley   +1 more source

Real-world evaluation of imipenem/cilastatin/relebactam across US medical centres

Journal of Global Antimicrobial Resistance
We assessed 160 patients who received imipenem/cilastatin/relebactam for ≥2 days. At treatment initiation, the median Charlson Comorbidity Index was 5, 45% were in the intensive care unit, and 19% required vasopressor support.
Ryan K. Shields, Emre Yücel, Vladimir Turzhitsky, Sanjay Merchant, Jae S. Min, Alexandre H. Watanabe   +5 more
doaj   +1 more source

Reversing Antibiotic Resistance: Strategies From Adjuvants to Innovative Therapeutics

MicrobiologyOpen, Volume 15, Issue 1, February 2026.
Molecular reversal strategies against antibiotic resistance act through three mechanisms: inhibiting resistance gene function, blocking horizontal gene transfer, and modulating host defense. Emerging technologies, such as CRISPR‐Cas gene editing, photodynamic therapy, nanotechnology, and ecological competition, further strengthen these approaches ...
Tianjiao Li, Fei Zeng, Jie Zhang, Yuangong Zhang, Wenjuan Yin   +4 more
wiley   +1 more source

Molecular epidemiological study of clinical Acinetobacter baumannii isolates: phenotype switching of antibiotic resistance [PDF]

, 2013
BackgroundThe presence of clinical Acinetobacter baumannii (A. baumannii) isolates with differing antibiotic resistance phenotypes in the same patient causes difficulties and confusion in treatment.
Chang-Hua Chen, Chieh-Chen Huang
core   +1 more source

Vancomycin‐Functionalized Nanodelivery Systems for Antibacterial Tissue Engineering Scaffolds

Advanced NanoBiomed Research, Volume 6, Issue 1, January 2026.
This review consolidates recent advancements in VAN nanoformulations, critically evaluating their design principles, release mechanisms, and efficacy profiles against resistant Gram‐positive pathogens. While promising in vitro and in vivo results have been demonstrated, the clinicaltranslation of these technologies necessitates further rigorous ...
Nima Beheshtizadeh, Mahsa Mohammadzadeh, Amir Abbas Seraji, Ali Pirsadeghi, Elham Zendedel, Maliheh Gharibshahian   +5 more
wiley   +1 more source

Imipenem resistance in clinical Escherichia coli from Qom, Iran [PDF]

, 2018
OBJECTIVE: The emergence of metallo-\u3b2-lactamase-producing Enterobacteriaceae is a worldwide health concern. In this study, the first evaluation of MBL genes, bla IMP and bla VIM , in Escherichia coli resistant to imipenem isolated from urine and ...
Esmkhani, M., Hashemi, A., Kermani, S., Piccirillo, A., Shams, E., Shams, S.   +5 more
core   +1 more source

Life‐Threatening Agranulocytosis Induced by Sinomenine Hydrochloride in Chronic Kidney Disease: A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Sinomenine, derived from Sinomenium acutum, is widely used in inflammatory diseases. However, its risk of inducing agranulocytosis is not widely appreciated. We report a life‐threatening case in a 40‐year‐old woman with chronic kidney disease (CKD; baseline estimated glomerular filtration rate [eGFR] as low as 36 mL/min/1.73 m2) who developed ...
Ping Xin, Ruoyan Liu, Yu Zhang, Bin Fu
wiley   +1 more source