Results 41 to 50 of about 12,794 (204)
Prophylaxis and antibiotic therapy in management protocols of patients treated with oral and intravenous bisphosphonates [PDF]
Osteonecrosis of the jaw (MRONJ) linked to bisphosphonate treatment has specific characteristics that render its therapeutic management challenging for clinicians.
Bermúdez Bejarano, Elena Beatriz +6 more
core +1 more source
Imipenem/Cilastatin versus Cefepime as Empiric Monotherapy for Fever in Neutropenic Patients after ematopoietic Stem Cell Transplantation [PDF]
Objective: To evaluate the potential advantages of imipenem/cilastatin in control of fever in neutro-penic HSCT recipients.Patients and Method: In this single-center study, 111 consecutive febrile episodes in 104 neutropenic HSCT recipients with a mean ...
C Kani +6 more
doaj +1 more source
Automated Detection of Systematic Off-label Drug Use in Free Text of Electronic Medical Records. [PDF]
Off-label use of a drug occurs when it is used in a manner that deviates from its FDA label. Studies estimate that 21% of prescriptions are off-label, with only 27% of those uses supported by evidence of safety and efficacy.
Jung, Kenneth +2 more
core +2 more sources
Evaluation of the Surgical and Pharmacological Treatment of Diabetic Foot Infection: A Retrospective Study [PDF]
BACKGROUND: Diabetic foot infection is a major cause of patient disabilities and lowers limb amputations, with high treatment costs and hospitalisation requirements.
Aliakbar, Adil Hassan +2 more
core +4 more sources
BACKGROUND:We demonstrated therapeutic nonequivalence of "bioequivalent" generics for meropenem, but there is no data with generics of other carbapenems.
Maria Agudelo +3 more
doaj +1 more source
ABSTRACT Burn injuries pose a significant challenge in resource‐limited settings, particularly during humanitarian crises. This study examines the epidemiology, management, and outcomes of burn patients at a tertiary hospital in Damascus, Syria, from 2021 to 2024.
Lorieh Domat +6 more
wiley +1 more source
Effective antibiotic conservation by emergency antimicrobial stewardship during a drug shortage [PDF]
We present the first description of an antimicrobial stewardship program (ASP) used to successfully manage a multi-antimicrobial drug shortage. Without resorting to formulary restriction, meropenem utilization decreased by 69% and piperacillin-tazobactam
Casabar, Ed +8 more
core +2 more sources
Postpartum Necrotizing Myometritis
ABSTRACT We present a case of postpartum necrotizing myometritis, a rare complication that often occurs following transcatheter arterial embolization for the treatment of postpartum hemorrhage, and its etiology is closely associated with uterine ischemia and bacterial infection.
Jiangyan Xie
wiley +1 more source
Rationale & Objective: Cilastatin is an inhibitor of drug metabolism in the proximal tubule that demonstrates nephroprotective effects in animals.
Dilaram Acharya +9 more
doaj +1 more source
Background Tigecycline, a first-in-class broad-spectrum glycylcycline antibiotic, has broad-spectrum in vitro activity against bacteria commonly encountered in complicated intra-abdominal infections (cIAIs), including aerobic and facultative Gram ...
Chen Xiaoping +15 more
doaj +1 more source

