Results 31 to 40 of about 12,794 (204)

Successful treatment of multiple microbleeds in a large area of the small bowel by transcatheter arterial embolization using imipenem/cilastatin as embolization material

Radiology Case Reports, 2023
A 44-year-old man with chronic idiopathic pseudo-intestinal obstruction and lumbar disc herniation presented with orthostatic dizziness, black vomiting, and stools.
Sakiko Hiraki, MD, Fumie Sato, MD, Ichiro Okada, MD, Masaya Osugi, MD, Yoshiya Watanabe, MD, Yoshiaki Ichinose, MD   +5 more
doaj   +1 more source

Simultaneous administration of imipenem/cilastatin/relebactam with selected intravenous antimicrobials, a stewardship approach.

PLoS ONE, 2020
Imipenem/cilastatin/relebactam is a β-lactam/β-lactamase inhibitor that has been recently FDA approved for complicated intra-abdominal and urinary tract infections under the brand name Recarbrio®.
Islam M Ghazi, Wasim S El Nekidy, Regan Asay, Paul Fimognari, Anthony Knarr, Mina Awad   +5 more
doaj   +1 more source

Determination of Antimicrobial Resistance and the Impact of Imipenem + Cilastatin Synergy with Tetracycline in Pseudomonas aeruginosa Isolates from Sepsis

Microorganisms, 2023
Pseudomonas aeruginosa is among the most ubiquitous bacteria in the natural world, exhibiting metabolic and physiological versatility, which makes it highly adaptable.
Telma de Sousa, Catarina Silva, Olimpia Alves, Eliana Costa, Gilberto Igrejas, Patricia Poeta, Michel Hébraud   +6 more
doaj   +1 more source

DRD2 Deficiency Underlies Pituitary Adenoma Dependent on Escherichia coli Translocation from the Gut

Advanced Science, Volume 13, Issue 24, 27 April 2026.
Dopamine receptor D2 (DRD2) deficiency disrupts epithelial barrier integrity in both the gut and pituitary gland, facilitating translocation of gut‐derived Escherichia coli into pituitary tissue. Intratumoral E. coli are phagocytosed by microglia, triggering GSDMD‐dependent pyroptosis and HMGB1 release, which subsequently activates MAPK signaling to ...
Xian‐jun Su, Li Ma, Xi Xiong, Jun‐hua Meng, Qi Wu, Yu Zhang, Shu‐guang Dong, Yue‐fei Wang, Jin‐hu Wu, Qing‐yuan Zeng, Hong‐feng Zhang, Li‐li Li, Liang Meng, Min Peng, Xiao‐dong Huang, Li‐quan Wu, Xiong Wang   +16 more
wiley   +1 more source

Development and application of an antibiotic spectrum index for benchmarking antibiotic selection patterns across hospitals [PDF]

, 2017
Standard metrics for antimicrobial use consider volume but not spectrum of antimicrobial prescribing. We developed an antibiotic spectrum index (ASI) to classify commonly used antibiotics based on activity against important pathogens.
Gerber, Jeffrey S, Hersh, Adam L, Kronman, Matthew P, Metjian, Talene A, Newland, Jason G, Ross, Rachael K   +5 more
core   +2 more sources

Divergent Silylmagnesiation of Ynamides: An Efficient and Versatile Entry to Polysubstituted Enamides

ChemistryEurope, Volume 4, Issue 4, April 2026.
A set of selective and divergent procedures for the silylmetallation of ynamides is reported. Upon simple reaction with a silyl‐Grignard reagent in the presence of catalytic amounts of copper bromide, a β‐selective, syn‐silylmagnesiation occurs affording a unique and selective access to polysubstituted silylated enamides.
Thibault Heymans, Gwilherm Evano
wiley   +1 more source

Antibiotic Adverse Reactions and Drug Interactions [PDF]

, 2008
Magnetic force microscopy (MFM) offers a unique insight into the nanoscopic scale domain structures of magnetic materials. However, MFM is generally regarded as a qualitative technique and, therefore, requires meticulous calibration of the magnetic ...
Dr.yekefallah, leili
core   +4 more sources

Development of a Short-Term Embolic Agent Based on Cilastatin for Articular Microvessels

Medicina
Background and Objectives: This study aimed to develop an embolic agent with short-term embolic effects using cilastatin as the basic material. Materials and Methods: The particle size distribution of 25 mg cilastatin-based short-term embolic agents was ...
Hyun Jin Kim, Areum Jeon, Eun Kyung Kang, Wen An, So Jung Lim, Kyu Chul Shin, Dong Hun Shin, Inyoung Hwang, Ju Seop Kang   +8 more
doaj   +1 more source

Clinical Outcome Associated With Beta‐Lactam Allergy Labels in Hospitalized Patients in Belgium

Clinical and Translational Allergy, Volume 16, Issue 4, April 2026.
ABSTRACT Background In the United States, beta‐lactam allergy labels (BLAL) are documented in 9%–16% of hospitalized patients and associated with worse clinical outcomes such as increased mortality, length of hospital stay (LOS), intensive care unit (ICU) admission, and use of alternative antibiotics, providing an incentive for broad delabeling ...
Liesbeth Gilissen, Greet Van De Sijpe, Annouschka Laenen, Peter Declercq, Dries Wets, Ileana Ghiordanescu, Anca Mirela Chiriac, Willy E. Peetermans, Paul De Munter, Isabel Spriet, Rik Schrijvers   +10 more
wiley   +1 more source

Risk of Acute Kidney Injury Associated With Nephrotoxic Burden in Hospitalized Patients: A Scoping Review

Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 891-904, April 2026.
Limited evidence exists synthesizing the risk of acute kidney injury (AKI) associated with the concomitant administration of multiple nephrotoxic drugs, and even less examining the concept of nephrotoxic burden. The objective of this scoping review was to (1) identify definitions of nephrotoxic burden; (2) methods used to quantify (use of calculations)
Wafa Alatawi, Jessica L. Wallace, Dhakrit Rungkitwattanakul, Britney A. Stottlemyer, Tiffany L. Tran, Melanie Manis Reida, Sandra L. Kane‐Gill   +6 more
wiley   +1 more source