Results 111 to 120 of about 53,416 (270)

Fusion of the β2‐adrenergic receptor with either Gαs or βarrestin‐2 produces constitutive signaling by each pathway and induces gain‐of‐function in BEAS‐2B cells

open access: yesFASEB BioAdvances, Volume 4, Issue 12, Page 758-774, December 2022., 2022
Abstract The β2AR is a prototypical G protein‐coupled receptor (GPCR) known to orchestrate different cellular responses by the stimulation of specific signaling pathways. The best‐established signaling pathways for the β2AR are the canonical Gs pathway and the alternative β arrestin 2 (βarr2) pathway.
Emilio Y. Lucero‐Garcia Rojas   +4 more
wiley   +1 more source

Dynamics of primary cilia in endothelial and mesenchymal cells throughout mouse lung development

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Cilia are specialized structures found on a variety of mammalian cells, with variable roles in the transduction of mechanical and biological signals (by primary cilia, PC), as well as in the generation of fluid flow (by motile cilia). Their critical role in the establishment of a left–right axis in early development is well described, as well ...
Stephen Spurgin   +8 more
wiley   +1 more source

Zooplankton act as cruise ships promoting the survival and pathogenicity of pathogenic bacteria

open access: yesMicrobiology and Immunology, Volume 66, Issue 12, Page 564-578, December 2022., 2022
Abstract Bacteria in general interact with zooplankton in aquatic ecosystems. These zooplankton–bacterial interactions help to shape the bacterial community by regulating bacterial abundances. Such interactions are even more significant and crucially in need of investigation in the case of pathogenic bacteria, which cause severe diseases in humans and ...
Ishara U. Perera   +4 more
wiley   +1 more source

FINE STRUCTURE OF THE CILIA OF ROTIFERS [PDF]

open access: bronze, 1961
Albert I. Lansing, François Lamy
openalex   +1 more source

Interspecific comparisons of anuran embryonic epidermal landscapes and energetic trade‐offs in response to changes in salinity

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Freshwater salinization is an emerging stressor in amphibian populations, and embryonic stages are most vulnerable. To better understand the variation in embryonic osmoregulation, we challenged embryos of two phylogenetically diverse anuran species, Xenopus laevis and Lithobates (Rana) sylvaticus, along a gradient of non‐lethal ...
Kourtnie Whitfield, Erica J. Crespi
wiley   +1 more source

Gender diversities and sex education

open access: yesJournal of Philosophy of Education, Volume 56, Issue 5, Page 654-662, October 2022., 2022
Abstract This article suggests that science‐based understandings of sex and gender can improve sex education by inviting students to consider what sex and gender mean and by encouraging recognition and respect in a gender‐diverse context. In addition, decolonising approaches to gender provide another route to sexuality education that is more attendant ...
Cris Mayo
wiley   +1 more source

Postnatal Dynamic Ciliary ARL13B and ADCY3 Localization in the Mouse Brain

open access: yesCells
Primary cilia are hair-like structures found on nearly all mammalian cell types, including cells in the developing and adult brain. A diverse set of receptors and signaling proteins localize within cilia to regulate many physiological and developmental ...
Katlyn K. Brewer   +5 more
doaj   +1 more source

Enigmatic Nodal and Lefty gene repertoire discrepancy: Latent evolutionary history revealed by vertebrate‐wide phylogeny

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Homology in vertebrate body plans is traditionally ascribed to the high‐level conservation of regulatory components within the genetic programs governing them, particularly during the “phylotypic stage.” However, advancements in embryology and molecular phylogeny have unveiled the dynamic nature of gene repertoires responsible for early ...
Shigehiro Kuraku
wiley   +1 more source

Three-dimensional flow in Kupffer's Vesicle [PDF]

open access: yesarXiv, 2016
Whilst many vertebrates appear externally left-right symmetric, the arrangement of internal organs is asymmetric. In zebrafish, the breaking of left-right symmetry is organised by Kupffer's Vesicle (KV): an approximately spherical, fluid-filled structure that begins to form in the embryo 10 hours post fertilisation.
arxiv  

Home - About - Disclaimer - Privacy