Results 111 to 120 of about 53,416 (270)
CENTRIOLES AND THE FORMATION OF RUDIMENTARY CILIA BY FIBROBLASTS AND SMOOTH MUSCLE CELLS [PDF]
Sergei P. Sorokin
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Abstract The β2AR is a prototypical G protein‐coupled receptor (GPCR) known to orchestrate different cellular responses by the stimulation of specific signaling pathways. The best‐established signaling pathways for the β2AR are the canonical Gs pathway and the alternative β arrestin 2 (βarr2) pathway.
Emilio Y. Lucero‐Garcia Rojas+4 more
wiley +1 more source
Dynamics of primary cilia in endothelial and mesenchymal cells throughout mouse lung development
Abstract Cilia are specialized structures found on a variety of mammalian cells, with variable roles in the transduction of mechanical and biological signals (by primary cilia, PC), as well as in the generation of fluid flow (by motile cilia). Their critical role in the establishment of a left–right axis in early development is well described, as well ...
Stephen Spurgin+8 more
wiley +1 more source
Zooplankton act as cruise ships promoting the survival and pathogenicity of pathogenic bacteria
Abstract Bacteria in general interact with zooplankton in aquatic ecosystems. These zooplankton–bacterial interactions help to shape the bacterial community by regulating bacterial abundances. Such interactions are even more significant and crucially in need of investigation in the case of pathogenic bacteria, which cause severe diseases in humans and ...
Ishara U. Perera+4 more
wiley +1 more source
FINE STRUCTURE OF THE CILIA OF ROTIFERS [PDF]
Albert I. Lansing, François Lamy
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Abstract Background Freshwater salinization is an emerging stressor in amphibian populations, and embryonic stages are most vulnerable. To better understand the variation in embryonic osmoregulation, we challenged embryos of two phylogenetically diverse anuran species, Xenopus laevis and Lithobates (Rana) sylvaticus, along a gradient of non‐lethal ...
Kourtnie Whitfield, Erica J. Crespi
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Gender diversities and sex education
Abstract This article suggests that science‐based understandings of sex and gender can improve sex education by inviting students to consider what sex and gender mean and by encouraging recognition and respect in a gender‐diverse context. In addition, decolonising approaches to gender provide another route to sexuality education that is more attendant ...
Cris Mayo
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Postnatal Dynamic Ciliary ARL13B and ADCY3 Localization in the Mouse Brain
Primary cilia are hair-like structures found on nearly all mammalian cell types, including cells in the developing and adult brain. A diverse set of receptors and signaling proteins localize within cilia to regulate many physiological and developmental ...
Katlyn K. Brewer+5 more
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Abstract Homology in vertebrate body plans is traditionally ascribed to the high‐level conservation of regulatory components within the genetic programs governing them, particularly during the “phylotypic stage.” However, advancements in embryology and molecular phylogeny have unveiled the dynamic nature of gene repertoires responsible for early ...
Shigehiro Kuraku
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Three-dimensional flow in Kupffer's Vesicle [PDF]
Whilst many vertebrates appear externally left-right symmetric, the arrangement of internal organs is asymmetric. In zebrafish, the breaking of left-right symmetry is organised by Kupffer's Vesicle (KV): an approximately spherical, fluid-filled structure that begins to form in the embryo 10 hours post fertilisation.
arxiv