Results 291 to 300 of about 164,456 (390)

An enzymatic cascade enables sensitive and specific proximity labeling proteomics in challenging biological systems. [PDF]

Nat Commun
Sroka TJ, Sanwald LK, Prasai A, Hoeren J, Trivigno V, Chaumet V, Krauß LM, Weber D, Yildiz D, von der Malsburg K, Walentek P, Haberkant P, Schrul B, Feistel K, Mick DU.   +14 more
europepmc   +1 more source

CCDC66 regulation of cytoskeleton and cilia stability is important for signaling and epithelial organization

Jovana Deretic, Seyma Cengiz-Emek, Seval Yılmaz, Elif Nur Firat‐Karalar   +3 more
openalex   +1 more source

Identification and Validation of Biomarkers in Chronic Rhinosinusitis With Nasal Polyps and Study of Their Associated Mechanisms

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Cell senescence (CS) and lipid metabolism (LM) disorders have been reported in chronic rhinosinusitis with nasal polyps (CRSwNP). However, the mechanism is still unclear. Methods Data were obtained from public databases; differential expression analysis and machine learning were performed to identify biomarkers and to understand the
Hui‐Yi Deng, Hui‐Jun Qiu, Ming‐Rui Pan, Qin‐Tai Yang   +3 more
wiley   +1 more source

Zmynd10 drives centriole biogenesis and multiciliogenesis through the transcriptional regulation of E2f4. [PDF]

Sci Rep
Liu Z, Wu Q, Zhou Z, Tan W, Zhong J, Fan S, Cao K, Huang L.   +7 more
europepmc   +1 more source

Photoreceptor Cilia and Retinal Ciliopathies.

Cold Spring Harbor Perspectives in Biology, 2017
K. Bujakowska, Qin Liu, E. Pierce
semanticscholar   +1 more source

Research Progress on Upper Airway Cough Syndrome

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Upper airway cough syndrome (UACS) has been identified as a significant contributor to chronic cough in various national guidelines. However, the complexity of its pathogenesis, the lack of clarity surrounding its diagnostic criteria, and its overlap with other etiologies of chronic cough present considerable challenges in both diagnosis and ...
Wan‐Ting Huang, Jia Chen
wiley   +1 more source

Loss of a primary cilia protein ARL13B promotes TGFβ-1 induced EMT of RPE in proliferative vitreoretinopathy via increasing Smad3 expression. [PDF]

Front Cell Dev Biol
Sui W, Ma X, Gong Y, Qiu K, Yuan M, Mao K, Qian X, Zeng J, Li Y, Lou B, Lin X, Zhou X.   +11 more
europepmc   +1 more source

Acetylcholine From Solitary Chemosensory Cell, Not Neuron, Regulates Basal Cell Fate Driving Eosinophilic Chronic Rhinosinusitis With Nasal Polyps

Allergy, EarlyView.
This study identifies that Ach levels are elevated in eCRSwNP and primarily released from SCCs rather than neurons. Ach induces epithelial remodeling in eCRSwNP by binding to M1R/M3R and activating YAP signaling in basal cells, driving basal cell hyperplasia and abnormal differentiation. Blocking M1R/M3R with TB inhibits eCRSwNP progression.
Bowen Zheng, Tao Lu, Ji Wang, Yalan Zhang, Panhui Xiong, Jieyu Zeng, Shuman Li, Yu Jiang, Yijun Liu, Longlan Shu, Yuan Chen, Yin Zhou, Yue Gu, Dayu Guan, Chenxi Li, Lei Zhao, Shujin Wang, Jie Liu, Xia Ke, Yang Shen, Yucheng Yang   +20 more
wiley   +1 more source

Enhanced Ciliogenesis of Human Bronchial Epithelial Cells by Simulated Microgravity. [PDF]

Life (Basel)
Bang SH, Hwang S, Choi SY, Kim HJ, Kim JH, Lee SH, Lee JW, Son KH.   +7 more
europepmc   +1 more source

Use of Small-Molecule Inhibitors of CILK1 and AURKA as Cilia-Promoting Drugs to Decelerate Medulloblastoma Cell Replication [PDF]

Sean H. Fu, C.-G. Park, Niyathi A. Shah, Ana Limerick, Ethan Powers, Cassidy B. Mann, Emily Hyun, Ying Zhang, D. Brautigan, Sijie Hao, Roger Abounader, Zheng Fu   +11 more
openalex   +1 more source