Results 81 to 90 of about 164,456 (390)
Charge‐Induced Morphing Gels for Bioinspired Actuation
Advanced Functional Materials, EarlyView.This study introduces a novel electroactive actuation mechanism that enables the gel material to generate substantial and reversible shape‐changing while preserving topological and isochoric (volumetric) equivalence. The resultant morphing behaviors can mimic the movements of muscle‐driven organelles in nature, including cilia‐like beating and ...
Ciqun Xu +4 more
wiley +1 more source
The ciliary GTPase Arl13b regulates cell migration and cell cycle progression [PDF]
, 2016 Acknowledgments We acknowledge Prof. Tamara Caspary from Emory University for kindly providing the cell lines, Linda Duncan from the University of Aberdeen Ian Fraser Cytometry Center for help with flow cytometry.
Clancy, Hannah +6 more
core +2 more sources
Three-dimensional architecture of epithelial primary cilia
Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance Primary cilia are sensory organelles that detect a wide range of extracellular signals for regulation of cell proliferation. Defects of their assembly/disassembly (primary ciliogenesis) and maintenance are linked to a variety of medical ...
Shufeng Sun +4 more
semanticscholar +1 more source
A Human Neural Tube Model Using 4D Self‐Folding Smart Scaffolds
Advanced Healthcare Materials, EarlyView.Induced pluripotent stem cells (iPSCs) exhibit features comparable to the inner cell mass of the human embryo. iPSCs are applied to a novel self‐folding 4D‐Neural Tube (4D‐NT) structure that mimics the neurulation process. This 4D‐NT model recapitulates early events of human neural development and represents a platform to explore neurodevelopmental ...
Claudia Dell'Amico +8 more
wiley +1 more source
Role of spatial heterogeneity on the collective dynamics of cilia beating in a minimal 1D model
, 2017 Cilia are elastic hairlike protuberances of the cell membrane found in various unicellular organisms and in several tissues of most living organisms. In some tissues such as the airway tissues of the lung, the coordinated beating of cilia induce a fluid ...
Dey, Supravat +2 more
core +1 more source
Ccdc11 is a novel centriolar satellite protein essential for ciliogenesis and establishment of left-right asymmetry [PDF]
, 2016 The establishment of left–right (L-R) asymmetry in vertebrates is dependent on the sensory and motile functions of cilia during embryogenesis. Mutations in CCDC11 disrupt L-R asymmetry and cause congenital heart disease in humans, yet the molecular and ...
Betleja, Ewelina +8 more
core +2 more sources
Purification and Immunostaining of Mouse Ependymal Ciliary Shafts
Bio-Protocol, 2022 Cilia and flagella are microtubule-based hair-like organelles protruding from the surface of most eukaryotic cells, and play essential roles in cell locomotion, left-right asymmetry, embryo development, and tissue homeostasis.
Kai Hao, Xueliang Zhu , Xiumin Yan
doaj +1 more source
eLife, 2018 Parkinson’s disease-associated LRRK2 kinase phosphorylates multiple Rab GTPases, including Rab8A and Rab10. We show here that LRRK2 kinase interferes with primary cilia formation in cultured cells, human LRRK2 G2019S iPS cells and in the cortex of LRRK2 ...
H. S. Dhekne +8 more
semanticscholar +1 more source
Bioprinting Organs—Science or Fiction?—A Review From Students to Students
Advanced Healthcare Materials, EarlyView.Bioprinting artificial organs has the potential to revolutionize the medical field. This is a comprehensive review of the bioprinting workflow delving into the latest advancements in bioinks, materials and bioprinting techniques, exploring the critical stages of tissue maturation and functionality.
Nicoletta Murenu +18 more
wiley +1 more source
Educational programme for patients with type 2 diabetes at community health centres : what is the evidence? [PDF]
, 2007 With increasing prevalence of diabetes mellitus type 2, more patients will require intensive management with diet, exercise, oral hypoglycaemic medication, and insulin replacement therapy in the primary care setting.
Cilia, Saviour
core