Results 291 to 300 of about 34,354 (355)

FMRP, an RNA-binding protein induced by the Mycoplasma pneumonia CARDS toxin, regulates multiciliogenesis and inflammation. [PDF]

Chin Med J (Engl)
Xu Y, Yang T, Shao S, Liu F, Song N, Li J.   +5 more
europepmc   +1 more source

Retinal thermal deformations measured with phase-sensitive optical coherence tomography in vivo. [PDF]

Light Sci Appl
Zhuo Y, Bhuckory M, Li H, Hattori J, Pham-Howard D, Veysset D, Ling T, Palanker D.   +7 more
europepmc   +1 more source

Bat Tongues and Foraging: Linking Morphology to Hunting Strategies

Integrative Zoology, EarlyView.
We linked the bat tongue's mediodorsal lobe (MDL), a muscular prominence, to foraging strategies. Aerial hawkers exhibit tall MDLs and prominent forward‐pointing papillae. The MDL may function as a barrier or filter, preventing unintentional ingestion of non‐food material, aiding in prey handling, and controlling food access during fast flight ...
Danilo Russo, Hugo Rebelo, Vanessa Mata, Ana Margarida Augusto, Luca Cistrone, Chiara Belli, Diogo Oliveira   +6 more
wiley   +1 more source

C. elegans PPEF-type phosphatase (Retinal degeneration C ortholog) functions in diverse classes of cilia to regulate nematode behaviors. [PDF]

Sci Rep
Barbelanne M, Lu Y, Kumar K, Zhang X, Li C, Park K, Warner A, Xu XZS, Shaham S, Leroux MR.   +9 more
europepmc   +1 more source

Weakened Airway Epithelial Junctions and Enhanced Neutrophil Elastase Release Contribute to Age‐Dependent Bacteremia Risk Following Pneumococcal Pneumonia

Aging Cell, EarlyView.
During spread of Streptococcus pneumoniae from the lung to the bloodstream, the pneumococcal pore‐forming toxin pneumolysin (PLY) disrupts apical junction complexes (AJCs) and triggers the transmigration of polymorphonuclear leukocytes (PMNs), which secrete tissue‐destructive neutrophil elastase.
Shuying Xu, Tianmou Zhu, Hongmei Mou, Shumin Tan, John M. Leong   +4 more
wiley   +1 more source

Differences in neuronal ciliation rate and ciliary content revealed by systematic imaging-based analysis of hiPSC-derived models across protocols. [PDF]

Front Cell Dev Biol
Haenseler W, Eschment M, Evans B, Brasili M, Figueiro-Silva J, Roethlisberger F, Abidi A, Jackson D, Müller M, Cowley SA, Bachmann-Gagescu R.   +10 more
europepmc   +1 more source

KIF9 Ameliorates Neuropathology and Cognitive Dysfunction by Promoting Macroautophagy in a Mouse Model of Alzheimer's Disease

Aging Cell, EarlyView.
KIF9 is downregulated in AD, accompanied by dysfunction in macroautophagy. Genetic upregulation of KIF9 enhances macroautophagy by promoting KLC1‐mediated anterograde transport of lysosomes, which effectively reduces Aβ deposition and alleviates cognitive impairments in AD.
Maoju Wang, Song Guo, Lilin Yi, Zhaolun Li, Xiuyu Shi, YePeng Fan, Man Luo, Yan He, Weihong Song, Yehong Du, Zhifang Dong   +10 more
wiley   +1 more source

The Nociceptor Primary Cilium Contributes to Mechanical Nociceptive Threshold and Inflammatory and Neuropathic Pain. [PDF]

J Neurosci
Fitzsimons LA, Staurengo-Ferrari L, Khomula EV, Bogen O, Araldi D, Bonet IJM, Green PG, Jordan EE, Sclafani F, Nowak CE, Moulton JK, Ganter GK, Levine JD, Tucker KL.   +13 more
europepmc   +1 more source

Transport, cilia, and PKD: must we in (cyst) on interrelationships? Focus on “Increased Na⁺/H⁺ exchanger activity on the apical surface of a cilium-deficient cortical collecting duct principal cell model of polycystic kidney disease”

, 2012
Ellis D. Avner, Alicia A. McDonough, William E. Sweeney   +2 more
openalex   +2 more sources

Transcriptional Heterogeneity and Differential Response of Rod Photoreceptor Pathway Uncovered by Single‐Cell RNA Sequencing of the Aging Mouse Retina

Aging Cell, EarlyView.
Healthy aging is accompanied by transcriptional dysregulation in retinal cells, leading to alterations in key molecular pathways and cellular responses, with the scotopic pathway being particularly affected. We show that rod photoreceptors, essential for initiating scotopic (low‐light) vision, exhibit selective vulnerability to aging‐associated ...
Laura Campello, Matthew J. Brooks, Benjamin R. Fadl, Hyo Sub Choi, Soumitra Pal, Anand Swaroop   +5 more
wiley   +1 more source