Glutamylation imbalance impairs the molecular architecture of the photoreceptor cilium. [PDF]
Mercey O+9 more
europepmc +1 more source
Abstract Background It is well‐established that spermatogenesis, semen quality, and reproductive hormones are interlinked. It is, however, less well‐described how various specific testicular histopathologies are linked to reproductive hormones and semen quality.
Gülizar Saritas+6 more
wiley +1 more source
Immunomodulatory potential of primary cilia in the skin. [PDF]
Sun J+6 more
europepmc +1 more source
Human asthenozoospermia: Update on genetic causes, patient management, and clinical strategies
Abstract Background In mammals, sperm fertilization potential relies on efficient progression within the female genital tract to reach and fertilize the oocyte. This fundamental property is supported by the flagellum, an evolutionarily conserved organelle, which contains dynein motor proteins that provide the mechanical force for sperm propulsion and ...
Emma Cavarocchi+5 more
wiley +1 more source
Mapping Protein Distribution in the Canine Photoreceptor Sensory Cilium and Calyceal Processes by Ultrastructure Expansion Microscopy. [PDF]
Takahashi K, Sudharsan R, Beltran WA.
europepmc +1 more source
The absence of both RIBC1 and RIBC2 induces decreased sperm motility and litter size in male mice
Abstract Background RIBC1 (RIB43A domain with coiled‐coils 1) and RIBC2 (RIB43A domain with coiled‐coils 2) are homolog proteins of RIB43a which is localized to microtubules in the cilia and flagella of unicellular organisms. Cryo‐electron microscopy and artificial intelligence studies showed that RIBC1 and RIBC2 are microtubule inner proteins (MIPs ...
Kento Katsuma+7 more
wiley +1 more source
RAB23loss-of-function mutation causes context-dependent ciliopathy in Carpenter syndrome
Leong W+4 more
europepmc +1 more source
A Taybi-Linder syndrome-related RTTN variant impedes neural rosette formation in human cortical organoids. [PDF]
Guguin J+16 more
europepmc +1 more source
Abstract Background Dry eye disease is a common ocular condition, affecting quality of life and function for many people worldwide. This systematic review evaluates the effectiveness and safety of intense pulsed light (IPL) therapy for dry eye symptoms due to meibomian gland dysfunction (MGD), as they are not yet established.
Nathalie Peira+5 more
wiley +1 more source
Loss of Kat2b impairs intraflagellar transport and the Hedgehog signaling pathway in primary cilia. [PDF]
Jun JH+5 more
europepmc +1 more source